BME Seminar Series: Nathan Doble, PhD, Associate Professor, Department of Optometry at The Ohio State University

Title: "In Vivo High Resolution Imaging of the Human Retina using Adaptive Optics"

ABSTRACT:

Adaptive optics (AO) has enabled in vivo imaging of the human retina with unprecedented resolution. By compensating for the deleterious effects of the corneal and lenticular aberrations, AO has allowed for the visualization of a variety of retinal cells. 

The presentation will begin with a brief review of the principle of AO and examples of current AO systems in our OSU laboratory including a flood illuminated fundus camera, a confocal scanning laser ophthalmoscope (SLO) and a combined AO-SLO-optical coherence tomography (OCT) system. 

Results from current projects, including imaging of cones and rods, measurement of the pointing of individual cones in both human and animals and various disease cases, will be presented.

BIO:

Dr. Nathan Doble is an Associate Professor in the College of Optometry at Ohio State University (OSU) joining the faculty in July 2013. Dr. Doble’s primary research interest is the development of high resolution optical imaging systems for the visualization of the human retina at the cellular level in vivo. 

Dr. Doble holds M.Sci. (St Andrews University, UK), M.Sc. (Imperial College, London, UK) and Ph.D. (University of Durham, UK) degrees in the fields of laser physics and adaptive optics, and performed postdoctoral work at the University of Rochester, NY, USA. Prior to OSU, Dr. Doble was a co-founder of Iris AO Inc., a high tech company specializing in the construction of MEMS based deformable mirrors for biomedical and industrial applications.