BME Seminar Series: Dr. Tadeusz Wysocki, University of Nebraska – Lincoln

Big Ten Seminar Exchange Speaker: Dr. Tadeusz Wysocki, University of Nebraska – Lincoln

Big Ten Seminar Exchange Speaker:

Dr. Tadeusz Wysocki, DSc, PhD, MEngSc, AvH, SMIEEE

Professor of Computer and Electronics Engineering

Director, Molecular Communications Laboratory

University of Nebraska – Lincoln

CEEN Dept., Peter Kiewit Institute 

 

"Use of Queueing Networks to Model Biological Processes at Sub-cellular Scale"

Abstract

In order to study biological processes that happen at sub-cellular level, like cell metabolism, viral infections or those processes that involve human interactions with living cells, like cell transfection or targeted drug delivery, accurate, scalable and inexpensive in-silico models are necessary. The seminar will present an application of queueing networks to develop such simulation models that can significantly speedup analysis of those processes and reduce expenses associated with laboratory experiments. The simulation in-silico can also help in identifying bottlenecks in signaling pathways and facilitate studying cell responses to changes in underlying conditions (e.g. initial concentrations of proteins, changing reaction speeds, etc.). The proposed solution is to use a modeling approach based on queuing theory and stochastic modeling to build simulation models tailored to particular biological/medical application. In the presentation, the fundamental aspects of the modeling as well as some of the developed models will be presented and results of simulations compared with the available experimental data.

 

Tadeusz Antoni Wysocki (IEEE M'94 - SM'98), received the M.Sc.Eng. degree with the highest distinction in telecommunications from the Academy of Technology and Agriculture, Bydgoszcz, Poland, in 1981. In 1984, he received his Ph.D. degree, and in 1990, was awarded a D.Sc. degree (habilitation) in telecommunications from the Warsaw University of Technology.

In 1992, he moved to Perth, Western Australia to work at Edith Cowan University. He spent the whole 1993 at the University of Hagen, Germany, within the framework of Alexander von Humboldt Research Fellowship. In December 1998, he moved to the University of Wollongong, NSW, as an Associate Professor, within the School of Electrical, Computer and Telecommunications Engineering. Since the fall of 2007, he has been with the University of Nebraska - Lincoln as a Professor of Electrical and Computer Engineering. He also holds a title of a Professor at the UTP University of Science and Technology, Bydgoszcz, Poland. The main areas of his research interests include: space-time signal processing, diversity combining, and indoor propagation of microwaves, molecular communications at nano-scale and its applications in microbiology and medicine including modeling of biological processes at cellular/sub-cellular scale and inter/intra-cell communications. He is an author or co-author of over 260 research papers.