BME Seminar Series: Dr. Joseph Irudayaraj, University of Illinois

Founder Professor of Bioengineering, Associate Head of Graduate Programs in Bioengineering, University of Illinois at Urbana-Champaign

Abstract:

"Perspectives on single cell analysis"

His group is interested in developing intracellular biosensors and single molecule methodologies for the quantification of molecular markers and understanding epigenetic mechanisms that define cells state or transition. They have utilized single molecule technologies based on fluorescence correlation spectroscopy, lifetime imaging, hyperspectral darkfield imaging, and SERS biosensors to monitor and quantify mRNA splicing, protein aggregation, and signaling pathway dynamics in live cells. In his talk he will discuss tools developed in his laboratory utilizing single molecule fluorescence and single particle plasmonics to monitor protein and mRNA activity related to epigenetics, kinase signaling, and alternative splicing.

 

Bio:

Dr. Irudayaraj has degrees in Agricultural and Biological Engineering (BS) from India, Biosystems Engineering (MS) and Computer Sci­ences (MS) from University of Hawaii, and a Ph.D in Biological Engineering from Purdue University. He has held faculty positions at Utah State, The Pennsylvania State University, and Purdue University prior to joining the University of Illinois at Urbana Champaign in 2017. At Purdue he served as the Interim Director of the Bindley Bioscience Center (BBC) for two years and Deputy Director of BBC for four years. He has also served as the Chair of the Graduate Programs in Agricultural and Biological Engineering (rated #1 US News and World Report), in addition to representing his Department and College in various committees at the College and University level. He moved to UIUC in 2017 as the Founder Professor of Bioengineering. He is also the Associate Head of the graduate programs in Bioengineering. His laboratory is located at the Mills Breast Cancer Center and the Micro & Nano Technology Laboratory. He is also the Co-Director of the Shared Resources of the Cancer Center at Illinois. He has published over 275 refereed journal articles (Google Scholar Citations: >14,500 and h-index: 69) on diverse areas of research with a primary emphasis on diagnostics and therapeutics for human health. He has supervised over 40 graduate students and 40 postdoctoral and visiting scholars