BME Seminar Series: Dr. Daniel Kim, Northwestern University

Daniel Kim, PhD
Professor of Radiology
​Director, Center for Translational Imaging Cardiovascular Imaging
MR Physics & Pulse Sequence Development
Northwestern University

Abstract: 

​"Rapid real-time CMR for patients with a cardiac implantable electronic device"

Cardiovascular magnetic resonance (CMR) delivers better value than other cardiac imaging modalities (SPECT, echocardiography) in patients with a cardiac implantable electronic device (CIED) because they have an underlying structural heart disease and often require complex downstream clinical decisions (new or worsening symptoms, VT ablation, battery replacement, CRT upgrades). Unfortunately, due to clinically significant image artifacts induced by CIEDs, arrhythmias and poor breath-holding during imaging, over 3 million Americans with a CIED may not benefit from a standard CMR. We have assembled a unique suite of CS-accelerated real-time wideband CMR pulse sequences together with inline image reconstruction methods for imaging patients with a CIED. Comprehensive real-time wideband stress CMR combining evaluation of ventricular function, perfusion, scar, and valve function for assessing new or worsening cardiovascular symptoms will enable a 47% reduction in healthcare charges ($1185.67 Medicare technical and physician fees) and 88% reduction in scan time (25 min) compared to current clinical practice combining stress SPECT ($1544.80, 3 hours) and resting echocardiography ($707.96, 25 min). Additionally, assessment of cardiac scar burden, location, and morphology assessed with CMR would be useful for predicting MACE and guiding EP procedures in ICM patients with an implantable cardioverter defibrillator (ICD).

Bio:

Dr. Kim joined the faculty of the Radiology department at Northwestern University Feinberg School of Medicine in 2016. He is currently a tenured Professor of Radiology with a Courtesy appointment in Biomedical Engineering. He received his Ph.D in Biomedical Engineering from the University of Virginia (2003) and post-doctoral training in cardiovascular MRI from New York University (2003-2006). His past academic positions including Assistant Professorship at New York University (2006-2011) and Associate Professorship at the University of Utah (2011-2005). 

Dr. Kim’s research spans from technology development to translational science in cardiovascular MRI. Building upon active collaboration with radiology and cardiology colleagues, his research focuses on addressing unmet clinical needs by developing new MRI pulse sequences and reconstruction methods and translating them to improve clinical management of heart disease.

To date, Dr. Kim has a total of > 60 peer-reviewed publications. As for extramural funding, Dr. Kim has received 10 awarded grants as a principal investigator from the NIH, AHA, and RSNA; he is currently the principal investigator on 2 NIH R01, 2 NIH R21, and 1 AHA awards. As an educator, Dr. Kim has mentored over 18 medical students, graduate students, and post-doctoral fellows over his career. As for awards, he is the recipient of the Distinguished Investigator Award by The Academy for Radiology & Biomedical Imaging Research. As for internal service, Dr. Kim supports our Radiology, MSTP, and Biomedical Engineering departments in various roles. As for external service, Dr. Kim serves a reviewer for NIH (standing member for EITA) and AHA study sections and numerous medical imaging journals (editorial board for NMR in Biomedicine) and gives invited lectures to society meetings such as ISMRM and SCMR.