Prof. Keith Gooch leads study of new drug to increase effectiveness of coronary bypass surgery

Prof. Keith Gooch, associate professor of BME, and colleagues recently published an important study showing the effectiveness of Protandim® -- a patented dietary supplement comprised of five highly synergistic herbal ingredients – in suppressing intimal hyperplasia (over-proliferation of cells that line the vessel wall), a common adverse event that limits the effectiveness of several types of vascular surgery. The study, sponsored by the American Heart Association and the National Institutes of Health, titled "Protandim attenuates intimal hyperplasia in human saphenous veins cultured ex vivo via a catalase-dependent pathway", explored the cellualr mechanism underlying this serious complication. The paper, co-authored by Binata Joddar, Rashmeet K. Reen, Michael S. Firstenberg, Saradhadevi Varadharaj, Joe M. McCord, and Jay L. Zweier, is published in the journal Free Radical Biology and Medicine may be found at the following link.