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Deborah Grzybowski

  • Assoc Professor of Practice, Dept of Engineering Education
  • 2070 Neil Avenue
    244 Hitchcock Hall
    Columbus, OH 43210
  • 614-292-1563

Honors

  • 20060101-20141201

    Intracranial Hypertension Research Foundation Scientific Advisory Panel.

  • 20140501

    Sphinx/Mortar Board Faculty Award.

  • 20120501

    Panhellenic Association Award for Outstanding Commitment to Student Education.

  • 20060101-20100101

    Brain Child Steering Committee.

  • 20050101

    Landacre Faculty Teaching Award.

Chapters

2013

  • 2013. "Chapter 11: Corneal Topographic Response to Swelling in Normal and post-LASIK Corneas." In ). Corneal Topography: from Theory to Practice, edited by Kılıç Uzbek A, Roberts CJ,

Journal Articles

2010

  • Gupta,Sumeet; Soellinger,Michaela; Grzybowski,Deborah,M; Boesiger,Peter; Biddiscombe,John; Poulikakos,Dimos; Kurtcuoglu,Vartan, 2010, "Cerebrospinal fluid dynamics in the human cranial subarachnoid space: an overlooked mediator of cerebral disease. I. Computational model." JOURNAL OF THE ROYAL SOCIETY INTERFACE 7, no. 49, 1195-1204 - 1195-1204.

2008

  • Lubow,Martin; Grzybowski,Deborah,M; Letson,Alan,D; Rennebohm,Robert; Susac,John,O, 2008, "Retinal arterio-arterial collaterals in SUSAC syndrome." RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES 28, no. 8, 1174-1174 - 1174-1174.
  • Lubow, M.; Grzybowski, D.M.; Letson, A.D.; Rennebohm, R. et al., 2008, "Fluorescein and indocyanine green angiographies in Susac syndrome.." Retina (Philadelphia, Pa.) 28, no. 8,
  • Baker KR; Zimmerman A; Grzybowski DM; McLaughlin WR; Katz SE; Pfriem DB; Good GW, 2008, "Optical quality and impact resistance comparisons of 2 football helmet faceshields.." Optometry (St. Louis, Mo.) 79, no. 8, 455 - 455.
  • Rennebohm RM; Lubow M; Rusin J; Martin L; Grzybowski DM; Susac JO, 2008, "Aggressive immunosuppressive treatment of Susac's syndrome in an adolescent: using treatment of dermatomyositis as a model.." Pediatric Rheumatology Online Journal 6, 3 - 3.

2006

  • Grzybowski, D. M., Rogers, N., Lembach, R., & Roberts, C., 2006, "The influence of refractive surgery-induced modulation of corneal biomechanics on corneal swelling response.." Journal of Biomechanics 39, no. 1, 387 - 387.
  • Grzybowski DM; Holman DW; Katz SE; Lubow M, 2006, "In vitro model of cerebrospinal fluid outflow through human arachnoid granulations.." Investigative Ophthalmology & Visual Science 47, no. 8, 3664 - 3664.

2000

  • Grzybowski, D.M.; Brodkey, R.S.; Friedman, M.H., 2000, "3-dimensional particle tracking velocimetry measurements of near-wall shear in human left coronary arteries." Annals of Biomedical Engineering 28, no. SUPPL. 1,

Presentations

  • "Spatial Comparison of Macromolecular Uptake in Porcine Iliac Arteries with CFD Derived Shear Maps." 2001, Presented at Biomedical Engineering Society Annual Fall Meeting,
  • "A Separation Technique to Isolate Arachnoid Cap Cells." 2004, Presented at Biomedical Engineering Society Annual Fall Meeting,
  • "Development of Explantation Model for Human Pia-Arachnoid Cells." 2004, Presented at COMPH Third Annual Graduate and Postgraduate Research Day,
  • "The Need for a Model to Study Cerebrospinal Fluid (CSF) Physiology and Pseudotumor Cerebri (PTC)." 2004, Presented at The Symposium of Neural Hydrodynamics,
  • "A Separation Technique to Isolate Arachnoid Cap Cells,." 2004, Presented at Symposium of Neural Hydrodynamics,
  • "Development of Explantation Model for Human Pia-Arachnoid Cells." 2004, Presented at Drug Information Association 40th Annual Meeting,
  • "An In-vitro model to study CSF hydrodynamics." 2004, Presented at AICHE 2004 Annual Meeting,
  • "Human Arachnoid Granulation Topography and Surface Area Quantification." 2005, Presented at Biomedical Engineering Society Annual Fall Meeting,
  • "Analysis of Body Morphology Characteristics and Vitamin A intake of Idiopathic Intracranial Hypertension Patients versus BMI-matched female controls." 2007, Presented at Department of Ophthalmology Research Symposium,
  • "The Effect of Vitamin A on Cultured Arachnoid Granulation Cells – Implications for Idiopathic Intracranial Hypertension." 2007, Presented at Department of Ophthalmology Research Symposium,
  • "Ultrastructural study of the permeability of in-vitro and ex-vivo human models of human arachnoid granulation CSF outflow pathway." 2007, Presented at Society for Research into Hydrocephalus and Spina Bifida,
  • "Reflectivity and Pachymetry Response to Corneal Swelling in Normal and Post LASIK Eyes with the SL-OCT." 2008, Presented at ARVO,
  • "Time-Course of the Biomechanical and Corneal Swelling Response to Nitrogen in Normal and Post LASIK Eyes." 2008, Presented at ARVO,
  • "Normal and Post LASIK Corneal Response to Swelling Using Reflectivity and Pachymetry with the SL-OCT." 2008, Presented at Department of Ophthalmology Research Symposium,,
  • "Retinol effects on CSF outflow through cultured human arachnoid granulation cells: implications for PTC,." 2008, Presented at Society for Research into Hydrocephalus and Spina Bifida Annual Meeting,
  • "Active transport of amyloid-beta in human arachnoid membrane.." 2008, Presented at International Conference on Alzheimer’s Disease,
  • "Vision research from an Engineering Perspective." 2008, Presented at VS 804, Anatomy and Physiology of the Visual System,
  • "Flow Matters." 2009,
  • "Swelling Analysis of Biomechanical Properties in the Post-LASIK Cornea.â€�." 2009, Presented at OSUMC Research Day,
  • "Transcranial Orbitotomy for Ocular-Orbital Histopathology: The FULL Autopsy is Not Full Enough." 2010, Presented at The Association for Research in Vision and Ophthalmology 2010 Annual Meeting,
  • "Non-Glaucomatous Human Trabecular Meshwork Biochemical Response to Laser Trabeculoplasty." 2004, Presented at COMPH Third Annual Graduate and Postgraduate Research Day,
  • "Analysis of corneal biomechanics based upon central and peripheral corneal thickness in normal and post refractive surgery eyes." 2004, Presented at Ophthalmology Research Symposium, Ohio State,
  • "Ex Vivo Model of CSF Outflow through Human Arachnoid Granulations." 2005, Presented at Biomedical Engineering Society Annual Fall Meeting,
  • "New Directions in CSF Outflow Research." 2005, Presented at 3rd Annual Symposium of Neural Hydrodynamics,
  • "Pressure Effect on Hydraulic Conductivity of Human Trabecular Meshwork Cells." 2005, Presented at Ohio Vision Loss Prevention Research Symposium,
  • "Analysis Of Corneal Biomechanics Based Upon Central And Peripheral Corneal Thickness, Topography And Wavefront Aberration In Normal And Post Refractive Surgery Eyes.." 2006, Presented at ARVO,
  • "Analysis Of Corneal Biomechanics Based Upon Central And Peripheral Corneal Thickness, Topography And Wavefront Aberration In Normal And Post Refractive Surgery Eyes." 2006, Presented at ARVO,
  • "A Retrospective Comparison of Photodynamic Therapy, Intravitreal Pegaptanib, and Intravitreal Bevacizumab for the Treatment of Neovascular Macular Degeneration." 2006, Presented at 26th Annual Research Symposium in Ophthalmology,
  • "Mechanism of CSF outflow through human arachnoid granulations using in-vitro and ex-vivo perfusion models." 2006, Presented at 50th Annual Meeting, Society for Research into Hydrocephalus and Spina Bifida,
  • "Human arachnoid granulation probability of occurrence and surface area quantification." 2006, Presented at 50th Annual Meeting, Society for Research into Hydrocephalus and Spina Bifida,
  • "IH Research, Part II: Current Research at Ohio State University." 2006, Presented at Intracranial Hypertension Research Foundation Annual Meeting,
  • "IH Research, Part I: Overview of Current Research and Areas of Future Study." 2006, Presented at Intracranial Hypertension Research Foundation Annual Meeting,
  • "CSF Outflow: The Arachnoid Membrane, Clearing the Drain." 2006, Presented at The Brain Child Hydrocephalus Conference,
  • "The Role of Vitamin A and Vitamin A Metabolites in the Pathogenesis of Idiopathic Intracranial Hypertension – A Pilot Study." 2007, Presented at Department of Ophthalmology Research Symposium,
  • "The role of vitamin A and its CSF metabolites in support of a novel mechanism of Idiopathic Intracranial Hypertension." 2007, Presented at Society for Research into Hydrocephalus and Spina Bifida,
  • "Amyloid-ß and Glaucoma: The Retinal Ganglion Cell - Neurotoxic Connection,." 2008, Presented at American Neuroophthalmology Society Annual Meeting,
  • "The Effect of Vitamin A on Cultured Arachnoid Granulation Cells: Implications for Idiopathic Intracranial Hypertension." 2008, Presented at North American Neuroophthalmology Society Annual Meeting,
  • "Alzheimer’s Disease, amyloid-beta, RAGE, LRP-1, arachnoid membrane." 2008, Presented at American Geriatric Society 2008 Annual Scientific Meeting,
  • "Retinal Capillary Perfusion Correlated with Cardio-Renal Angiopathy." 2008, Presented at Department of Ophthalmology Research Symposium,
  • "Comparison of Previously Used Football Helmet Face Shields to New Football Helmet Face Shields for Optical Quality and Impact Resistance." 2008, Presented at Department of Ophthalmology Research Symposium,
  • "Investigation of microtopography regulated human trabecular meshwork culture for glaucoma treatment.." 2009, Presented at Association for Research in Vision and Ophthalmology,
  • "Development of in vitro 3D model of human trabecular meshwork using polymer microfibers." 2009, Presented at Association for Research in Vision and Ophthalmology,
  • "Correlation of Optic Nerve Sheath Diameter by Ultrasonography with Intracranial Pressure in Children.." 2009, Presented at Department of Ophthalmology Research Symposium,
  • "Pseudotumor Cerebri in Children." 2009, Presented at Department of Ophthalmology Research Symposium,
  • "Nanoengineered Polymer Scaffold With Controllable Porosity Towards 3D in vitro Trabecular Meshwork Model." 2010, Presented at The Association for Research in Vision and Ophthalmology 2010 Annual Meeting,
  • "Bridging the Gap between Cardiovascular and Ophthalmic Engineering Applications." 2002, Presented at Biomedical Engineering Seminar Series,
  • "Arachnoid Granulations and Cerebrospinal Fluid Flow: An In Vitro Model for Blood Brain Barrier." 2004, Presented at BMES 2004 Fall Meeting,
  • "Human Arachnoid Granulation Cell Culture and Characterization: A Key Toward Unlocking the Brain-Blood-Barrier." 2004, Presented at Upper Midwest Neuroophthalmology Group Annual Meeting,
  • "Development of 2-D and 3-D culturing techniques to isolate Pia-Arachnoid Cells from human brain tissue." 2004, Presented at American Institute of Chemical Engineers 2004 Annual Meeting,
  • "Vitamin A Transduction Pathway in Static and Perfused Human Arachnoid Granulation Cell Cultures.." 2005, Presented at Biomedical Engineering Society Annual Fall Meeting,
  • "Blood Brain Barrier." 2005, Presented at North American Neuroophthalmology Society Annual Meeting,
  • "Arachnoid Granulations and Cerebrospinal Fluid Flow: An In-Vitro Model for the Blood Brain Barrier." 2005, Presented at North American Neuroophthalmology Society Annual Meeting,
  • "Structural Integrity of LASIK versus Non-LASIK Treated Cadaver Eyes." 2005, Presented at Ophthalmology Research Symposium,,
  • "The Role of Vitamin A and Vitamin A Metabolites in the Pathogenesis of Idiopathic Intracranial Hypertension – A Pilot Study." 2007, Presented at ARVO,
  • "Cytokine & MMP Production After Laser Irradiation in Responsive vs Non-Responsive Cultured Human TM EC." 2007, Presented at ARVO,
  • "Ex vivo model of CSF outflow through Human Arachnoid Granulations: Mechanisms of fluid outflow and implications for Idiopathic Intracranial Hypertension research." 2007, Presented at Department of Ophthalmology Research Symposium,
  • "Clinical comparison of corneal and scleral IOP measurements when measured by the Tonopen in relation to corneal thickness." 2007, Presented at Department of Ophthalmology Research Symposium,
  • "RAGE and LRP-1 expression at the arachnoid membrane-venous circulation interface in human brain tissue." 2008, Presented at OSUMC Research Day,
  • "CSF Outflow Revisited: A New Paradigm." 2008, Presented at Animal Model Hydrocephalus Meeting, Society for Research into Hydrocephalus and Spina Bifida Annual Meeting,
  • "Papilledema with Visual Loss." 2008, Presented at Joint Meeting of the American Academy of Ophthalmology and European Society of Ophthalmology (SOE), NANOS Symposium: Top Five to Stay Alive: Five Neuro-ophthalmology Pearls and Pitfalls for the Generalist,
  • "Isolation of Hydrostatic Pressure Effects on Irradiated Trabecular Meshwork Endothelial Cells." 2009, Presented at OSUMC Research Day,
  • "Retinal Capillary Perfusion Correlated with Cardio-Renal Angiopathy." 2009, Presented at Department of Ophthalmology Research Symposium,
  • "Transcranial Orbitotomy for Ocular-Orbital Histopathology: The FULL Autopsy is Not Full Enough." 2010, Presented at 9th Annual OSUMC Trainee Research Day,
  • "Analysis of Biomechanical Properties in the Swollen Post-LASIK Cornea." 2010, Presented at 9th Annual OSUMC Trainee Research Day,
  • "Model of the Effect of Hypercholesterolemia in Swine on the Arterial Uptake of Macromolecules." 2001, Presented at Biomedical Engineering Society Annual Fall Meeting,
  • "Localization of Carbonic Anhydrase in Human Choroid Plexus and Arachnoid Granulations." 2003, Presented at Ophthalmology Research Symposium,
  • "Development of a Separation Technique to Isolate Pia-Arachnoid Cells." 2004, Presented at COMPH Third Annual Graduate and Postgraduate Research Day,
  • "An In-Vitro Model to Study CSF Physiology and Pseudotumor Cerebri." 2004, Presented at The Symposium of Neural Hydrodynamics,
  • "Development of 2D & 3D culture techniques to isolate Pia-Arachnoid (PA) Cells from human brain tissue." 2004, Presented at BMES Fall Meeting,
  • "Hydraulic Conductivity of Human Arachnoid Granulation Cells (AGs) in an In Vitro Model of CSF Outflow." 2005, Presented at Biomedical Engineering Society Annual Fall Meeting,
  • "Pressure Effect on Hydraulic Conductivity of Human Trabecular Meshwork Cells." 2005, Presented at Association for Research in Vision and Ophthalmology,
  • "Hydraulic Conductivity of Human Arachnoid Granulation Cap Cells in an In Vitro Model of Cerebrospinal Fluid Outflow." 2005, Presented at ARVO,,
  • "Vitamin A Transduction Pathway in Human Arachnoid Granulation Tissue and Culture: Implication in the Etiology of Idiopathic Intracranial Hypertension." 2005, Presented at 3rd Annual Symposium of Neural Hydrodynamics,
  • "Pressure Effect on Hydraulic Conductivity of Human Trabecular Meshwork Cells." 2005, Presented at ARVO: Association for Research in Vision and Ophthalmology,
  • "CSF Outflow: Whole Tissue Perfusion of Human Arachnoid Granulations." 2005, Presented at 3rd Annual Symposium of Neural Hydrodynamics,
  • "Analysis of Corneal Biomechanics Based Upon Central and Peripheral Corneal Thickness, Topography and Wavefront Aberration in Normal and Post Refractive Surgery Eyes,." 2005, Presented at Ophthalmology Research Symposium,
  • "The Relationship Between Intraocular Pressure and Intracranial Pressure in Pseudotumor Cerebri." 2005, Presented at Ophthalmology Research Symposium,
  • "Quantifying Cosmetic Success in Browlift and Blepharoplasty Surgery." 2005, Presented at Ophthalmology Research Symposium,
  • "Aesthetic Comparison of the Results of Combined Browlift and Blepharoplasty versus Blepharoplasty Alone." 2005, Presented at American Society of Ophthalmic Plastic and Reconstructive Society Fall Meeting,
  • "Mechanism of CSF Outflow Through Human Arachnoid Granulations." 2006, Presented at World Ophthalmology Congress,
  • "Human Arachnoid Granulation Probability of Occurrence and Surface Area Quantification." 2006, Presented at World Ophthalmology Congress,
  • "CSF Arachnoid Granulation Outflow Mechanism.." 2006, Presented at North American Neuroophthalmology Society Annual Meeting,
  • "CSF Arachnoid Granulation Outflow Mechanism." 2006, Presented at North American Neuroophthalmology Society Annual Meeting,
  • "Human Arachnoid Granulation Probability of Occurrence and Surface Area Quantification." 2007, Presented at North American Neuroophthalmology Society Annual Meeting,
  • "Mechanism of CSF Outflow Through Human Arachnoid Granulations using in-vitro and ex-vivo Perfusion Models." 2007, Presented at North American Neuroophthalmology Society Annual Meeting,
  • "Odor Sensitivity Threshold in Patients With Pseudotumor Cerebri." 2007, Presented at ARVO,
  • "Immunohistochemical staining of Beta adrenergic receptors on human arachnoid granulations and choroid plexus." 2007, Presented at Department of Ophthalmology Research Symposium,
  • "A Retrospective Study of the Visual Outcome of Idiopathic Intracranial Hypertension Patients after Optic Nerve Sheath Fenestration." 2007, Presented at Department of Ophthalmology Research Symposium,
  • "Comparison of two football helmet face shields, Oakley and Nike, for optical quality and impact resistance." 2007, Presented at Department of Ophthalmology Research Symposium,
  • "Cytopathology of Hydrocephalus." 2007, Presented at The Brain Child Steering Committee,
  • "Heat Shock Protein Expression Following Micropulse and Continuous Wave Diode Laser Irradiation of Cultured Human Trabecular Meshwork Endothelial Cells." 2008, Presented at ARVO,
  • "Perfusion Response and Associated Heat Shock Protein Expression Following Micropulse and Continuous Wave Diode Laser Irradiation of Cultured Human Trabecular Meshwork Endothelial Cells." 2008, Presented at Department of Ophthalmology Research Symposium,
  • "Human Arachnoid Membrane: Active transport of amyloid-beta." 2008, Presented at Society for Research into Hydrocephalus and Spina Bifida Annual Meeting,
  • "CSF Outflow Models: Human Arachnoid Membrane As A Pathway For A-beta Clearance." 2008, Presented at International Conference on Alzheimer’s Disease,
  • "Retinal Capillary Modeling for Systemic Disease." 2009, Presented at OSUMC Research Day,
  • "Retinal Capillary Perfusion Correlated with Cardio-Renal Angiopathy.." 2009, Presented at Department of Ophthalmology Research Symposium,
  • "Evaluation of Corneal Changes in Obstructive Sleep Apnea." 2009, Presented at Department of Ophthalmology Research Symposium,
  • "Electrospun Micro/Nano Polymer Fibers for Construction of an In Vitro Human Trabecular Meshwork Model." 2009, Presented at Department of Ophthalmology Research Symposium,
  • "Arachnoid pathways for CSF absorption." 2009, Presented at Hydrocephalus 2009 NIH Workshop; Improving Outcomes in Hydrocephalus: Bridging the Gap Between Basic Science and Clinical Management,
  • "Topographic Effect of Micro/Nanoengineered Polymer Substrates on Cultured Trabecular Meshwork Cells." 2011, Presented at The Association for Research in Vision and Ophthalmology 2011 Annual Meeting,
  • "Swelling Analysis Of Thickness, Curvature, And Biomechanical Properties In The Post-LASIK Cornea." 2011, Presented at The Association for Research in Vision and Ophthalmology 2011 Annual Meeting,
  • "The Olin institute experience." 2014, Presented at EEIC Seminar Series,

Papers in Proceedings

2017

  • Dixon, K.; Grzybowski, D.M.; Le, J.V.; Castro, C.E. et al. "Making meaning through art-integrated engineering." (6 2017).
  • Grzybowski, D.M.; Wild, T.; Yang, S.J. "Engineering education for visually impaired students." (6 2017).

2016

  • Grzybowski, D.M.; Dixon, K. "RTP design as the practice of probability: Engaging adolescent girls in art-infused engineering." (6 2016).
  • Bannerman, R.T.; Theiss, A.; Grzybowski, D.M. "MAKER: Utilizing 3-D printing of nanotechnology design project prototypes to enhance undergraduate learning." (6 2016).
  • Cohen, W.F.; Enders, J.J.; Kolotka, K.L.; Freuler, R.J. et al. "MAKER: Applications of 3-D printing and laser cutting in the development of autonomous robotics." (6 2016).

2015

  • Grzybowski, D.M.; Demel, J.T. "Assessment of inverted classroom success based on Felder's index of learning styles." (1 2015).

2013

  • Tague, J., Czocher, J.A., Baker, G.R., Harper, K.A., Grzybowski, D.M., and Freuler, R. "Engineering Faculty Perspectives on Mathematical Preparation of Students." in International Conference on Engineering Education and Research. (7 2013).
  • Grzybowski, D.M., Abernathy, S., Boyd, A.C., Cain, D., Hird, N.L., Madhavan, R.R., Shi, Y., Spang, M.T., Strickland, A.A., and Clingan, P.A. "Student Assisted Approach to Curriculum Changes to Facilitate a Flipped Classroom for First-Year Engineering Micro-/Nano-technology 'Lab-on-a-chip' Research Project." in International Conference on Engineering Education and Research. (7 2013).

2008

  • Price, S., Kim, B., Roberts, C.J., Grzybowski, D.M. and Zhao, Y., "Investigating the Porosity of Trabecular Meshwork Using Microfabricated Structures for Glaucoma Treatments,." in Proceeding of the 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences (microTAS '08). (1 2008).

2005

  • Holman, D.W.; Grzybowski, D.M.; Katz, S.E.; Lubow, M. "An in vitro model of the cerebrospinal outflow pathway through the arachnoid granulations." (12 2005).

2002

  • Friedman, M.H., Grzybowski, D.M., Hazel, A.L., Himburg, H. A., and LaMack, J.A "Wall Shear Stress and Albumin Permeability at the Porcine Aortic Trifurcation." in Proc. IV World Congress of Biomechanics. (8 2002).