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Metin Gurcan

  • Adjunct Professor, SBS-Biomedical Informatics
  • 1800 Cannon Drive
    310G Lincoln Tower
    Columbus, OH 43210
  • 614-688-9857

Honors

  • 20151101-20201101

    USCAP Short Course Presenter.

  • 20090101-20161201

    The Ohio State University Comprehensive Cancer Center REAP Award.

  • 20140201

    Nominated for a Distinguished Undergraduate Research Mentor award.

  • 20130101

    Senior Member of SPIE.

  • 20100101

    Best Paper Award.

  • 20080101-20100101

    Young Investigator Award.

  • 20070101

    caBIG Embodying the Vision Award.

  • 20070101

    Senior member of IEEE.

  • 19960101-19980101

    Visiting Researcher.

  • 19920101

    British Foreign Office, Foreign Commonwealth Organization Award.

Books

1999

  • Gurcan MN. 1999. "Computer-aided Diagnosis in Radiology." Bilkent University.

1993

  • Gurcan MN. 1993. "An Optical Fibre Link Employing Digital Filtering." University of Manchester Institute of Science and Technology.

Edited Books

2016

  • Gurcan MN, Madabhushi A. 2016. "Medical Imaging 2016: Digital Pathology." SPIE.

2015

  • Gurcan MN, Madabhushi A. 2015. "Medical Imaging 2015: Digital Pathology." SPIE.

2014

  • Gurcan MN, Madabhushi A. 2014. "Medical Imaging 2014: Digital Pathology." SPIE.

2013

  • Gurcan MN, Madabhushi A. 2013. "Medical Imaging 2013: Digital Pathology." SPIE.

Chapters

2009

  • 2009. "Processing of Large-Scale Biomedical Images on a Cluster of Multi-Core CPUs and GPUs." In Trends in High Performance and Large Scale Computing, edited by Wolfgang Gentzsch, Lucio Grandinetti, Gerhard Joubert,

2008

  • 2008. "Service-based Access to and Processing of Large Scientific Datasets," High Performance Computing (HPC) and Grids in Action." In High Performance Computing (HPC) and Grids in Action, Advances in Parallel Computing,

Unknown

  • "Image Analysis Fundamentals in Digital Pathology." In Digital Pathology, edited by Liron Pantanowitz and Anil V Parwani,

Journal Articles

2015

  • Fauzi,Mohammad,Faizal Ahmad; Khansa,Ibrahim; Catignani,Karen; Gordillo,Gayle; Sen,Chandan,K; Gurcan,Metin,N, 2015, "Computerized segmentation and measurement of chronic wound images." COMPUTERS IN BIOLOGY AND MEDICINE 60, 74-85 - 74-85.
  • Smith B, Arabandi S, Brochhausen M, Calhoun M, Ciccarese P, Doyle S, Gibaud B, Goldberg I, Kahn CE Jr, Overton J, Tomaszewski J, Gurcan MN, 2015, "Biomedical Imaging Ontologies: A Survey and Proposal for Future Work." Journal of Pathology Informatics 6, 37 - 37.
  • Fauzi,Mohammad,FaizalAhmad; Gokozan,Hamza,Numan; Elder,Brad; Puduvalli,Vinay,K; Pierson,Christopher,R; Otero,José,Javier; Gurcan,Metin,N, 2015, "A multi-resolution textural approach to diagnostic neuropathology reporting.." Journal of neuro-oncology 124, no. 3, 393-402 - 393-402.
  • Niazi,Muhammad,KK; Dhulekar,Nimit; Schmidt,Diane; Major,Samuel; Cooper,Rachel; Abeijon,Claudia; Gatti,Daniel,M; Kramnik,Igor; Yener,Bulent; Gurcan,Metin; Beamer,Gillian, 2015, "Lung necrosis and neutrophils reflect common pathways of susceptibility to Mycobacterium tuberculosis in genetically diverse, immune-competent mice." DISEASE MODELS & MECHANISMS 8, no. 9, 1141-1153 - 1141-1153.
  • Fauzi,Mohammad,Faizal Ahmad; Pennell,Michael; Sahiner,Berkman; Chen,Weijie; Shana'ah,Arwa; Hemminger,Jessica; Gru,Alejandro; Kurt,Habibe; Losos,Michael; Joehlin-Price,Amy; Kavran,Christina; Smith,Stephen,M; Nowacki,Nicholas; Mansor,Sharmeen; Lozanski,Gerard; Gurcan,Metin,N, 2015, "Classification of follicular lymphoma: the effect of computer aid on pathologists grading." BMC MEDICAL INFORMATICS AND DECISION MAKING 15, 115 - 115.
  • Fauzi,Mohammad,Faizal Ahmad; Pennell,Michael; Sahiner,Berkman; Chen,Weijie; Shana'ah,Arwa; Hemminger,Jessica; Gru,Alejandro; Kurt,Habibe; Losos,Michael; Joehlin-Price,Amy; Kavran,Christina; Smith,Stephen,M; Nowacki,Nicholas; Mansor,Sharmeen; Lozanski,Gerard; Gurcan,Metin,N, 2015, "Classification of follicular lymphoma: the effect of computer aid on pathologists grading." BMC MEDICAL INFORMATICS AND DECISION MAKING 15, 115 - 115.
  • Niazi,Muhammad,KK; Dhulekar,Nimit; Schmidt,Diane; Major,Samuel; Cooper,Rachel; Abeijon,Claudia; Gatti,Daniel,M; Kramnik,Igor; Yener,Bulent; Gurcan,Metin; Beamer,Gillian, 2015, "Lung necrosis and neutrophils reflect common pathways of susceptibility to Mycobacterium tuberculosis in genetically diverse, immune-competent mice." DISEASE MODELS & MECHANISMS 8, no. 9, 1141-1153 - 1141-1153.

2014

  • Niazi,M,Khalid Khan; Yearsley,Martha,M; Zhou,Xiaoping; Frankel,Wendy,L; Gurcan,Metin,N, 2014, "Perceptual clustering for automatic hotspot detection from Ki-67-stained neuroendocrine tumour images." JOURNAL OF MICROSCOPY 256, no. 3, 213-225 - 213-225.
  • Kornaropoulos,Evgenios,N; Niazi,M,Khalid Khan; Lozanski,Gerard; Gurcan,Metin,N, 2014, "Histopathological Image Analysis for Centroblasts Classification Through Dimensionality Reduction Approaches." CYTOMETRY PART A 85, no. 3, 242-255 - 242-255.

2013

  • Lozanski,Gerard; Pennell,Michael; Shana'ah,Arwa; Zhao,Weiqiang; Gewirtz,Amy; Racke,Frederick; Hsi,Eric; Simpson,Sabrina; Mosse,Claudio; Alam,Shadia; Swierczynski,Sharon; Hasserjian,Robert,P; Gurcan,Metin,N, 2013, "Inter-reader variability in follicular lymphoma grading: Conventional and digital reading.." Journal of pathology informatics 4, no. 30, 1-9 - 1-9.

2012

  • Mahoney,Emilia; Lucas,David,M; Gupta,Sneha,V; Wagner,Amy,J; Herman,Sarah,EM; Smith,Lisa,L; Yeh,Yuh-Ying; Andritsos,Leslie; Jones,Jeffrey,A; Flynn,Joseph,M; Blum,Kristie,A; Zhang,Xiaoli; Lehman,Amy; Kong,Hui; Gurcan,Metin; Grever,Michael,R; Johnson,Amy,J; Byrd,John,C, 2012, "ER stress and autophagy: new discoveries in the mechanism of action and drug resistance of the cyclin-dependent kinase inhibitor flavopiridol." BLOOD 120, no. 6, 1262-1273 - 1262-1273.
  • Payne,Philip,RO; Jackson,Rebecca,D; Best,Thomas,M; Borlawsky,Tara,B; Lai,Albert,M; James,Stephen; Gurcan,Metin,N, 2012, "Applying knowledge-anchored hypothesis discovery methods to advance clinical and translational research: the OAMiner project." JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION 19, no. 6, 1110-1114 - 1110-1114.

2011

  • Belkacem-Boussaid K; Samsi S; Lozanski G; Gurcan MN, 2011, "Automatic detection of follicular regions in H&E images using iterative shape index.." Computerized Medical Imaging And Graphics 35, no. 7-8, 592 - 592.
  • Prescott JW; Best TM; Swanson MS; Haq F; Jackson RD; Gurcan MN, 2011, "Anatomically anchored template-based level set segmentation: application to quadriceps muscles in MR images from the Osteoarthritis Initiative.." Journal Of Digital Imaging 24, no. 1, 28 - 28.
  • Lézoray O; Gurcan M; Can A; Olivo-Marin JC, 2011, "Special issue on whole slide microscopic image processing.." Computerized Medical Imaging And Graphics 35, no. 7-8, 493 - 493.

2010

  • Gurcan, M.N.; Roysam, B.; Dhawan, A.P.; Wang, L.V, 2010, "Editorial to Special Letters Issue on Emerging Technologies in Multiparameter Biomedical Optical Imaging and Image Analysis." IEEE Transactions on Biomedical Imaging 57, no. 10, 2551-2552 - 2551-2552.
  • Swanson, M.; Prescott, J.; Best, T.M.; Powell, K.; Jackson, R.D.; Haq, F.; Gurcan, M.N, 2010, "Semi-automated segmentation to assess the lateral meniscus in normal and osteoarthritis knees." Osteoarthritis and Cartilage 18, no. 3, 344-353 - 344-353.
  • Samsi, S.; Lozanski, G.; Shana’ah, A.; Krishanmurthy, A.; Gurcan, M.N, 2010, "Detection of follicles from IHC stained slides of follicular lymphoma using iterative watershed." IEEE Transactions on Biomedical Imaging 57, no. 10, 2609-2612 - 2609-2612.
  • Sertel, O.; Lozanski, G.; Shana’ah, A.; Gurcan, M.N, 2010, "Computer-aided Detection of Centroblasts for Follicular Lymphoma Grading using Adaptive Likelihood based Cell Segmentation." IEEE Transactions on Biomedical Imaging 57, no. 10, 2613-2616 - 2613-2616.
  • Prescott, J.; Zhang, D.; Wang, J.Z.; Mayr, N.A.; Yuh, W.T.C.; Saltz, J.H.; Gurcan, M.N, 2010, "Temporal Analysis of Tumor Heterogeneity and Volume for Cervical Cancer Treatment Outcome Prediction: Preliminary Evaluation." Journal of Digital Imaging 23, no. 3, 342-357 - 342-357.
  • Belkacem-Boussaid, K.; Pennell, M.; Lozanski, G.; Shana’ah, A.; Gurcan, M.N, 2010, "Computer-aided classification of centroblast cells in follicular lymphoma." Analytical and Quantitative Cytology and Histology 5, no. 32, 254-260 - 254-260.

2009

  • Erdal, S.; Catalyurek, U. V.; Payne, P. R.; Kamal, J.; Saltz, J. H.;Gurcan, M. N., 2009, "A Knowledge-Anchored Integrative Image Search and Retrieval System." Journal of Digital Imaging 22, no. 2, 166-182 - 166-182.
  • Sharma, A.; Pan, T.; Cambazoglu, B. B.; Hastings, S.; Gurcan, M. N.; Kurc, T.; Saltz, J., 2009, "VirtualPACS- A Federating Gateway to Access Remote Image Data Resources Over the Grid." Journal of Digital Imaging 22, no. 1, 1-10 - 1-10.
  • Cooper, L.; Sertel, O.; Kong, J.; Lozanski, G.; Huang, K.; Gurcan, M.N, 2009, "Feature-Based Registration of Histopathology Images with Different Stains: An Application for Computerized Follicular Lymphoma Prognosis." Computer Methods and Programs in Biomedicine 96, no. 3, 182-192 - 182-192.
  • Gurcan, M.N.; Boucheron, L.; Can, A.; Madabhushi, A.; Rajpoot, N.; Yener, B, 2009, "Histopathological Image Analysis: A review." IEEE Reviews in Biomedical Engineering 2, 147-171 - 147-171.
  • TrimboliA, Cantemir-StoneCZ, Li F,Wallace JA,Merchant A, Creasap N, Thompson JC, Caserta E, Wang H, Chong J-L, Naidu S, Wei G, Sharma SM, Stephens JA, Fernandez SA, GurcanMN, Weinstein MB, Barsky SH, Yee L, Roso lTJ, Stromberg PC, Robinson ML, Pepin F, Hallett M, Park M, Ostrowski C, Leone G, 2009, "Pten in Stromal Fibroblasts Suppresses Mammary Epithelial Tumors." Nature 461, 1084-1091 - 1084-1091.
  • Ruiz,Antonio; Sertel,Olcay; Ujaldon,Manuel; Catalyurek,Umit; Saltz,Joel; Gurcan,Metin,N, 2009, "Stroma classification for neuroblastoma on graphics processors." INTERNATIONAL JOURNAL OF DATA MINING AND BIOINFORMATICS 3, no. 3, 280-298 - 280-298.
  • Sertel, O.; Kong, J.; Shimada, H.; Catalyurek, U. V.; Saltz, J. H.; Gurcan, M. N., 2009, "Computer-aided prognosis of neuroblastoma on whole-slide images: Classification of stromal development." Pattern Recognition 42, no. 6, 1093-1103 - 1093-1103.
  • Ruiz, A.; Sertel, O.; Ujaldon, M.; Catalyurek, U.; Saltz, J.; Gurcan, MN, 2009, "Stroma classification for neuroblastoma on graphics processors." International Journal of Data Mining and Bioinformatics 3, no. 3, 280-298 - 280-298.
  • Sertel, O.; Kong, J.; Catalyurek, U. V.; Lozanski, G.; Saltz, J.; Gurcan, M. N., 2009, "Histopathological image analysis using model-based intermediate representations and color texture: Follicular lymphoma grading." The Journal of Signal Processing Systems 55, 160-183 - 160-183.
  • Prescott, J.; Zhang, D.; Wang, J. Z.; Mayr, N. A.; Yuh, W. T. C.; Saltz, J. H.; Gurcan, M. N., 2009, "Analysis of tumor heterogeneity and temporal change for cancer treatment outcome prediction: Application to cervical cancer." Journal of Digital Imaging 23, no. 3, 342-357 - 342-357.

2008

  • Sertel,Olcay; Kong,Jun; Lozanski,Gerard; Catalyurek,Umit; Saltz,Joel,H; Gurcan,Metin,N, 2008, "Computerized microscopic image analysis of follicular lymphoma." MEDICAL IMAGING 2008: COMPUTER-AIDED DIAGNOSIS, PTS 1 AND 2 6915, 691535 - 691535.
  • Saltz, JH; Kurc, T; Hastings, S; Langella, S; Oster, S; Ervin, D; Sharma, A; Pan, T; Gurcan, MN; Permar, J; Ferreira, R; Payne, P; Catalyurek, UV; Caserta, E; Leone, G; Ostrowski, MC; Madduri, R; Foster, I; Madhavan, S; Buetow, KH; Shanbhag, K; Siegel, E, 2008, "e-Science, caGrid, and Translational Biomedical Research." IEEE Computer 41, 58-66 - 58-66.
  • Kumar, V. S.; Narayanan, S.; Kurc, T. M.; Kong, J.; Gurcan, M. N.; Saltz, J. H., 2008, "Supporting analysis and semantic querying in large biomedical image datasets." IEEE Computer 41, no. 4, 52-59 - 52-59.
  • Prescott,Jeffrey,W; Zhang,Dongqing; Wang,Jian,Z; Mayr,Nina,A; Yuh,William,TC; Saltz,Joel; Gurcan,Metin, 2008, "Cancer treatment outcome prediction by assessing temporal change: application to cervical cancer." MEDICAL IMAGING 2008: COMPUTER-AIDED DIAGNOSIS, PTS 1 AND 2 6915, 69152X - 69152X.
  • Sertel,Olcay; Kong,Jun; Lozanski,Gerard; Shana'ah,Anva; Catalyurek,Umit; Saltz,Joel; Gurcan,Metin, 2008, "Texture classification using nonlinear color quantization: Application to histopathological image analysis." 2008 IEEE INTERNATIONAL CONFERENCE ON ACOUSTICS, SPEECH AND SIGNAL PROCESSING, VOLS 1-12 5300, 597-600 - 597-600.

2007

  • Pan, T. C.; Gurcan, M. N.; Langella, S.; Oster, S.; Hastings, S. L.; Sharma, A.; Rutt, B.; Ervin, D. W.; Kurc, T. M.; Siddiqui, K. M.; Saltz, J. H.; Siegel, E., 2007, "GridCAD: A grid-based computer-aided detection system." Radiographics 27, 889-897 - 889-897.
  • Kong,Jun; Shimada,Hiroyuki; Boyer,Kim; Saltz,Joel; Gurcan,Metin, 2007, "Image analysis for automated assessment of grade of neuroblastic differentiation." 2007 4TH IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING : MACRO TO NANO, VOLS 1-3 12, 61-64 - 61-64.
  • Pan,Tony,C; Gurcan,Metin,N; Langella,Stephen,A; Oster,Scott,W; Hastings,Shannon,L; Sharma,Ashish; Rutt,Benjamin,G; Ervin,David,W; Kurc,Tahsin,M; Siddiqui,Khan,M; Saltz,Joel,H; Siegel,Eliot,L, 2007, "Informatics in radiology: GridCAD: grid-based computer-aided detection system.." Radiographics 27, no. 3, 889-897 - 889-897.
  • Kong,Jun; Sertel,Olcay; Shimada,Hiroyuki; Boyer,Kim; Saltz,Joel; Gurcan,Metin, 2007, "Computer-aided grading of neuroblastic differentiation: Multi-resolution and multi-classifier approach." 2007 IEEE INTERNATIONAL CONFERENCE ON IMAGE PROCESSING, VOLS 1-7 23, 2777-2780 - 2777-2780.
  • Gurcan,Metin,N; Kong,Jun; Sertel,Olcay; Cambazoglu,B,Barla; Saltz,Joel; Catalyurek,Umit, 2007, "Computerized pathological image analysis for neuroblastoma prognosis.." AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium 120, 304-308 - 304-308.

2006

  • Gurcan,Metin,N; Pan,Tony; Shimada,Hiro; Saltz,Joel, 2006, "Image analysis for neuroblastoma classification: segmentation of cell nuclei.." Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 1, 4844-4847 - 4844-4847.

2002

  • Gurcan,M,N; Chan,H,P; Sahiner,B; Hadjiiskii,L,M; Petrick,N; Helvie,M,A, 2002, "Optimal neural network architecture selection: Effects on computeraided detection of mammographic microcalcifications." MEDICAL IMAGING 2002: IMAGE PROCESSING, VOL 1-3 4684, 1325-1330 - 1325-1330.
  • Hadjiiski,L; Chan,H,P; Sahiner,B; Petrick,N; Helvie,M,A; Roubidoux,M; Gurcan,M, 2002, "Computer-aided characterization of malignant and benign microcalcification clusters based on the analysis of temporal change of mammographic features." MEDICAL IMAGING 2002: IMAGE PROCESSING, VOL 1-3 4684, 749-753 - 749-753.

2001

  • Hadjiiski, L.; Sahiner, B.; Chan, H-P.; Petrick, N.; Helvie, M. A.; Gurcan, M. N., 2001, "Analysis of Temporal Change of Mamographic Features: Computer-Aided Classification of Malignant and Benign Breast Masses." Medical Physics 28, no. 11, 2309-2317 - 2309-2317.
  • Paquerault,S; Chan,H,P; Sahiner,B; Petrick,N; Hadjiiski,L; Gurcan,M,N; Zhou,C; Helvie,M,A, 2001, "Prediction of object location in different mammographic views using geometrical models." IWDM 2000: 5TH INTERNATIONAL WORKSHOP ON DIGITAL MAMMOGRAPHY 5, 748-755 - 748-755.

1999

  • Gurcan,M,N; Yardimci,Y; Cetin,A,E, 1999, "Microcalcification segmentation and mammogram image enhancement using nonlinear filtering." PROCEEDINGS OF THE IEEE-EURASIP WORKSHOP ON NONLINEAR SIGNAL AND IMAGE PROCESSING (NSIP'99) 78, 588-592 - 588-592.

Unknown

  • Niazi K, Chung JH, Heaton-Johnson KJ, Martinez D, Castellanos R, Irwin MS, Master S, Pawel B, Gurcan MN, Weiser DA, "Advancing diagnostic risk stratification of high-risk neuroblastoma using computerized image analysis and proteomic profiling." Pediatric and Developmental Pathology

Presentations

  • "Medical Image Analysis: Visual Decomposition and Modeling." 2013, Presented at International Workshop on Computational Intelligence for Multimedia Understanding,
  • "Clinical Image Analysis Laboratory at The Ohio State University." 2013, Presented at Battelle Invited, Invited by Aaron Sander, Ph.D.,
  • "How ontologies can help in addressing the big data challenges of pathology imaging: perspectives from a collaborating pathologist and image scientist." 2015, Presented at The Role of Ontology in Big Cancer Data, National Center for Ontological Research,
  • "Clinical Image Analysis: Affecting Decisions." 2014, Presented at CIM Workshop on Mathematics and Medicine, Invited by Ewert Bengtsson, PhD,
  • "Image analysis algorithms: What can they do for pathology?." 2014, Presented at Annual Digital Pathology Meeting,
  • "Digital Image Analysis." 2015, Presented at Digital Pathology Congress,
  • "Medical Image Analysis: Visual Decomposition and Modeling." 2014, Presented at UCSF Radiology Invited Speaker Series, Invited by Duygu Tosun-Turgut, PhD.,
  • "Clinical Image Analysis: Closing the loop." 2014, Presented at Nordic Digital Pathology Symposium, Invited by Claes Lundström, PhD,
  • "From Pixels to Diagnosis: Image Analysis for Digital Pathology." 2015, Presented at Pathology Visions, Invited Talk. Invited by Eric Glassy, MD, Chair of Digital Pathology Association.,
  • "Histopathological Image Analysis: Now and Future." 2014, Presented at Neurology Department Ground Rounds,
  • "Histopathological Image Analysis: Slides to Information." 2016, Presented at Pathology Department Ground Rounds,
  • "Medical Image Analysis: Information-based Visual Decomposition and Modeling." 2013, Presented at IUPUI Invited,
  • "Computer-Assisted Histopathological Image Analysis: Expectations and Challenges." 2011, Presented at Trends in Experimental Pathology: Imaging of Model Organisms/Experimental Trends - "Brave New World," Invited by John Tomaszewski, MD.,
  • "Hot spot detection for histopathological images." 2015, Presented at MMTC Digital Pathology, Invited by Liron Pantowitz, MD.,
  • "Histopathological Image Analysis: Closing the Loop." 2015, Presented at FDA Invited Speaker. Invited by Berkman Sahiner, PhD.,
  • "Image Processing Applications in Molecular Biology and Genetics." 1999, Presented at Seminar Series, Department of Molecular Biology and Genetics,
  • "Accurate Nodule Volume Estimation from Helical CT Images: Comparison of Slice-based and Volume-based Methods." 2003, Presented at 89th Scientific Assembly and Annual Meeting of Radiological Society of North America (RSNA),
  • "gridIMAGE: A Grid Computing Platform for Radiological and Pathological Image Analysis." 2007, Presented at SIIM 2007 Annual Meeting,
  • "Computer-assisted Microscopic Image Analysis for Clinical Research." 2008, Presented at The Mass Spectroscopy Research Center,
  • "Computer-assisted Medical Image Analysis." 2010,
  • "Computer-assisted identification of boundaries of lesions in cutaneous lymphomas." 2010, Presented at First World Congress for Cutaneous Lymphomas,
  • "The Six Million Dollar Doctor: How to Enhance Speed and Vision of Doctors?." 2012, Presented at Case Western Reserve University, Department of Computer Science, invited talk as part of the department's monthly talk series. Invited by Dr. Mehmet Koyuturk,
  • "Computer-aided Analysis of Virtual Slides for Neuroblastoma." 2006, Presented at Advances of Neuroblastoma Research (ANR) Workshop: Pathology in the 21st Century,
  • "Image analysis for neuroblastoma classification: Hysteresis thresholding for nuclei segmentation." 2006, Presented at APIII 2006,
  • "Computer-assisted Histopathology: Experience with Neuroblastoma and Follicular Lymphoma." 2008, Presented at Workshop on Bio-image Informatics: Biological Imaging, Computer Vision and Data Mining 2008,
  • "Clinical Image Analysis at BMI." 2009, Presented at OCCBIO 2009,
  • "Improvement of Computrized Detection of Microcalcifications using a Convolution Neural Network Architecture Selected by an Automated Optimization Algorithm." 2001, Presented at Medical Image Perception Conference IX,
  • "Accurate Nodule Volume Estimation from Helical CT Images: Comparison of Slice-based and Volume-based Methods." 2002, Presented at 88th Scientific Assembly and Annual Meeting of Radiological Society of North America,
  • "Computer vision in neuroblastoma: computer-aided prognosis." 2010, Presented at Advances in Neuroblastoma Research (ANR 2010),
  • "Multi-scale analysis of histpathological images: Experience with follicular lymphoma and neuroblastoma." 2011, Presented at NSF-RPI Workshop,
  • "Comparison of Simulated Annealing and Genetic Algorithm for Optimization of Neural Network Architectures." 2000, Presented at Food and Drug Administration,
  • "Knee strength predicts loss of function and decline in physical activity in participants with osteoarthritis: A 2-year followup of the OAI study." 2009, Presented at World Congress on Osteoarthritis,
  • "Computer-aided Prognosis of Neuroblastoma." 2010,
  • "Computer-aided Image Analysis: A new paradigm for biology and medicine." 2012, Presented at Battelle,
  • "Computer-assisted Medical Image Analysis." 2010, Presented at Invited speaker, invited by Eva Örndahl, PhD,
  • "Computer-aided Diagnosis and Prognosis in Pathology." 2011, Presented at Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, as part of the monthly departmental seminars, invited by the Dean of the College.,
  • "Computer-aided Diagnosis and Prognosis in Pathology." 2012, Presented at Pathology and Laboratory Medicine Ground Rounds,
  • "Microscopic Image Analysis: Closing the loop." 2014, Presented at Bioimage Informatics,
  • "Defining molecular events for targeted therapy of glioblastoma using digital image analysis." 2016, Presented at OSU Comprehensive Cancer Center Ground Rounds,
  • "Radiology to Pathology: Closed Loop Evaluation for Image Analysis." 2016, Presented at Pathology Informatics, Radiology Pathology Convergence Session, Invited lecturer. Invited by Dr. Mark Tuthill,
  • "Computer-aided Diagnosis: Computerized Lung Nodule Detection on Thoracic CT Images." 2000, Presented at Cancer Research Symposium,
  • "Information-based Visual Decomposition and Modeling of Medical Images." 2013, Presented at Emory Invited, Invited by Joel Saltz, MD, PhD,
  • "Computer-assisted Biomedical Image Analysis." 2011, Presented at Invited Talk, Invited by Alexandre Cunha, PhD,
  • "Microscopic Image Analysis for Pathology and Biology." 2012, Presented at Monthly Seminar Series, Invited Talk, Invited by Orhan Arikan, Ph.D.,
  • "An Engineer’s Quest for Better Diagnosis." 2012, Presented at IEEE Turkey Student Innovation Competition, Invited Talk, Invited by Mustafa Karaman, Ph.D.,
  • "Imaging biomarkers for osteoarthritis research." 2009, Presented at Toward Quantitative Imaging: Reading Room of the Future, RSNA 2009,

Papers in Proceedings

2016

  • Abas, F; Gokozan HN; Goksel B;Otero JJ; Gurcan MN "Interoperative neuropathology of glioma recurrence: Cell detection and classification." in Conference on Medical Imaging - Digital Pathology. (3 2016).
  • Niazi KK; Parwani A; Gurcan MN "Computer-assisted bladder cancer grading: alpha-shapes for color space decomposition." in Conference on Medical Imaging - Digital Pathology. (3 2016).

2015

  • Akakin, Hatice C, Gokozan, Hamza, Otero, Jose, Gurcan, Metin N "An adaptive algorithm for detection of multiple-type, positively stained nuclei in IHC images with minimal prior information: application to OLIG2 staining for gliomas." in SPIE Medical Imaging. (1 2015).
  • Gokozan,Hamza; Fauzi,Mohammad,Ahmad; Elder,Brad; Winter,Jessica; Puduvalli,Vinay; Pierson,Christopher; Gurcan,Metin; Otero,Jose "Towards Single Cell Pathway Component Analysis in Diagnostic Pathology: Digitized Image Analysis." in Experimental Biology Meeting 2015. (4 2015).

2014

  • Fauzi,Mohammad,Faizal Ahmad; Khansa,Ibrahim; Catignani,Karen; Gordillo,Gayle; Sen,Chandan,K; Gurcan,Metin,N "Segmentation and Automated Measurement of Chronic Wound Images: Probability Map Approach." in Conference on Medical Imaging - Computer-Aided Diagnosis. (1 2014).
  • Acar E, Lozanski G, Gurcan MN "Tensor-based computation and modeling in multi-resolution digital pathology imaging: Application to Follicular Lymphoma Grading." in 2nd Conference on Medical Imaging - Digital Pathology. (1 2014).
  • Gokozan,H,N; Ahmad,Fauzi,MF; Elder,B; Winter,J; Puduvalli,V,K; Gurcan,M,N; Otero,J,J "Enhancing pathology diagnostic and prognostic reporting using digitized image analysis." in 18th International Congress of Neuropathology. (9 2014).

2013

  • Niazi,M,Khalid Khan; Pennell,Michael; Elkins,Camille; Hemminger,Jessica; Jin,Ming; Kirby,Sean; Kurt,Habibe; Miller,Barrie; Plocharczyk,Elizabeth; Roth,Rachel; Ziegler,Rebecca; Shana'ah,Arwa; Racke,Fred; Lozanski,Gerard; Gurcan,Metin,N "Entropy based quantification of Ki-67 positive cell images and its evaluation by a reader study." in 9th Conference on Digital Pathology at the SPIE Medical Imaging Symposium. (1 2013).

2012

  • Prescott,Jeffrey,W; Best,Thomas,M; Haq,Furqan; Pennell,Michael; Jackson,Rebecca; Gurcan,Metin "Vastus Intermedius Cross-sectional Area Is Associated With Radiographic Severity Of Knee Osteoarthritis." (7 2012).

2011

  • Prescott,Jeffrey,W; Best,Thomas,M; Haq,Furqan; Pennell,Michael; Jackson,Rebecca; Gurcan,Metin "Vastus Intermedius Cross-sectional Area Is Associated With Radiographic Severity Of Knee Osteoarthritis." (5 2011).

2010

  • Dundar, M.; Badve, S.; Raykar, V.; Jain, R.; Sertel, O.; Gurcan, M.N "A multiple instance learning approach toward optimal classification of pathology slides: Classifying intraductal breast lesions as a case study." in International Conference on Pattern Recognition (ICPR) 2010. (8 2010).
  • Belkacem-Boussaid, K.; Pennell, M.; Lozanski, G.; Shana’ah, A.; Gurcan, M.N "Effect of pathologist agreement on evaluating a computer-assisted system: Recognizing centroblasts in follicular lymphoma cases." in IEEE ISBI 2010. (4 2010).
  • Prescott, JW, Haq F, Best T, Jackson R, Gurcan MN "An analysis of methods for the selection of atlases for use in medical image segmentation." in SPIE Medical Imaging 2010. (2 2010).
  • Sertel, O.; Dogtas, B.; Chiu, C.S.; Gurcan, M.N "Muscle histology image analysis for sarcopenia: Registration of successive sessions with distinctive atpase activity." in IEEE ISBI 2010. (4 2010).
  • Sertel O, Catalyurek U, Lozanski G, Shana’ah A, Gurcan MN "An image analysis approach for detecting malignant cells in digitized H&E-stained histology images of follicular lymphoma." in International Conference on Pattern Recognition (ICPR) 2010. (10 2010).
  • Gurcan,Metin,N; Madabhushi,Anant; Rajpoot,Nasir "Pattern Recognition in Histopathological Images: An ICPR 2010 Contest." in 20th International Conference on Pattern Recognition Conference. (1 2010).
  • Ababneh, S.; Gurcan, M.N "An Efficient Graph-Cut Segmentation for Knee Bone Osteoarthritis Medical Images." in IEEE International Conference on Electro/Information Technology (EIT 2010). (5 2010).

2009

  • Samsi, S.; Krishnamurthy, A.K.; Groseclose, M.; Caprioli, R.M.; Lozanski, G.; Gurcan, M.N "Imaging Mass Spectrometry Analysis for Follicular Lymphoma Grading." in IEEE EMBC 2009. (9 2009).
  • Sertel, O.; Catalyurek, U.V.; Shimada, H.; Gurcan, M.N "Computer-aidedprognosis of neuroblastoma: Detection of Mitosis and Karyorrhexis cells in digitized histological images." in IEEE EMBC 2009. (9 2009).
  • Sertel, O.; Catalyurek, U.V.; Shimada, H.; Gurcan, M.N "A combined computerized-system for classifying digitized whole-slide neuroblastomahistology: Model-based structural features." in MICCAI 2009. (9 2009).
  • Prescott, J.W.; Swanson, M.S.; Haq, F.; Best, T.M.; Powell, K.; Jackson, R.; Gurcan, M.N "An Automated Method for Femur Segmentation for Osteoarthritis Research." in IEEE EMBC 2009. (9 2009).
  • Prescott, J.W.; Swanson, M.; Powell, K.; Haq, F.; Best, T.; Jackson, R.; Gurcan, M.N "Template-based level-set segmentation using anatomical information." in IEEE ISCIS 2009. (9 2009).
  • Oger, M.; Belhomme, P.; Gurcan, M.N "Classification of low-resolutionvirtual slides from breast tumor sections: Comparison between global and local analysis." in IEEE EMBC 2009. (9 2009).
  • Belkacem-Boussaid, K.; Sertel, O.; Lozanski, G.; Shana¹aah, A.; Gurcan, M.N "Extraction of color features in the spectral domain to recognize centroblasts in histopathology." in IEEE EMBC 2009. (9 2009).
  • Mumcuoglu, E.U.; Prescott, J.; Baker, B.N.; Clifford, B.; Long, F.; Castile, R.; Gurcan, M.N "Image Analysis for Cystic Fibrosis: Automatic Lung Airway Wall and Vessel Measurement on CT Images." in IEEE EMBC 2009. (9 2009).
  • Teodoro, G.; Sachetto, R.; Sertel, O.; Gurcan, M.N.; Meira, W.; Catalyurek, U.V.; Ferreira, R "Coordinating the use of GPU and CPU for improving performance of compute intensive applications." in IEEE Cluster 2009. (8 2009).
  • Prescott, J.W.; Priddy, M.; Swanson, M.S.; Haq, F.; Best, T.M.; Powell, K.; Jackson, R.; Gurcan, M.N "An Automated Method for Intramuscular Fat Detection in Quadriceps Muscles for Osteoarthritis Diagnosis." in IEEE EMBC 2009. (9 2009).

2008

  • Sertel, O.; Kong, J.; Lozanski, G.; Catalyurek, U.; Saltz, J. H.;Gurcan, M. N. "Computerized Microscopic Image analysis of Follicular Lymphoma." in SPIE Medical Imaging. (2 2008).
  • Prescott, J.; Zhang, D.; Wang, J.; Mayer, N.; Saltz, J. H.; Gurcan , M. N. "Outcome Prediction for Radiation Treatment of Cervical Cancer by Assessing tumor Heterogeneity and Temporal Change." in SIIM 2008. (5 2008).
  • Ruiz, A.; Kong, J.; Ujaldon, M.; Boyer, K; Saltz, J.H.; Gurcan, M.N. "Pathological Image Segmentation for Neuroblastoma Using the GPU." in IEEE ISBI. (5 2008).
  • Kong, J.; Sertel, O.; Shimada, H.; Boyer, K.L.; Saltz, J.H.; Gurcan, M.N. "A Multi-resolution Image analysis System for Computer-assisted Grading of Neuroblastoma Differentiation." in SPIE Medical Imaging. (1 2008).
  • Prescott, J.; Saltz, J.H.; Gurcan, M.N.; Donqing, Z.; Wang, J.; Mayr, N.; Yuh, W. "Cancer Treatment Outcome Prediction by Assessing Temporal Change: Application to Cervical Cancer." in SPIE Medical Imaging Conference. (1 2008).
  • Sertel, O.; Kong, J.; Shimada, H.; Catalyurek, U.V.; Saltz, J.H.; Gurcan, M.N. "Computer-aided Prognosis of Neuroblastoma: Classification of Stromal Development on Whole-slide Images." in SPIE Medical Imaging. (2 2008).
  • Sertel, O.; Kong, J.; Catalyurek, U.V.; Lozanski, G.; Shanaah, A.; Saltz, J.H.; Gurcan, M.N. "Texture Classification Using Nonlinear Color Quantization: application to Histopathological Image analysis." in IEEE ICASSP. (1 2008).

2007

  • Kong, J.; Sertel, O.; Shimada H.; Boyer, K.; Saltz, J.H; Gurcan, M.N. "Computer-aided Grading of Neuroblastic Differentiation: Multi-resolution and Multi-classifier Approach." in IEEE ICIP 2007: International Conference on Image Processing. (9 2007).
  • Ruiz, A.; Sertel, O.; Ujaldon, M.; Catalyurek, U.V.; Gurcan, M.N.; Saltz, J.H. Pathological Image Analysis Using the GPU: Stroma Classification for Neuroblastoma. in 2007 IEEE International Conference on Bioinformatics and Biomedicine. http://doi.ieeecomputersociety.org/10.1109/BIBM.2007.56, (1 2007).
  • Kong, J.; Shimada, H.; Boyer, K;Saltz, J.H.; Gurcan, M.N. "Image Analysis for Automated Assessment of Grade of Neuroblastic Differentiation." in IEEE ISBI2007: International Symposium on Biomedical Imaging: From nano to macro. (4 2007).
  • Kong,Jun; Sertel,Olcay; Gewirtz,Amy; Shana'ah,Arwa; Racke,Frederick; Zhao,John; Boyer,Kim; Catalyurek,Umit; Gurcan,Metin; Lozanski,Gerard "Development of computer based system to aid pathologists in histological grading of follicular lymphomas." in 49th Annual Meeting of the American-Society-of-Hematology. (11 2007).
  • Kumar, V.S.; Kurc, T.M.; Kong, J.; Catalyurek, U.V.;Gurcan, M.N.; Saltz, J.H. "Performance vs. Accuracy Trade-offs for Large-scale Image Analysis Applications." in Proceedings of the IEEE Cluster 2007. (9 2007).
  • Cambazoglu, B.B.; Sertel, O.; Kong, J.; Saltz, J.H.; Gurcan, M.N; Catalyurek, U.V. "Efficient Processing of Pathological Images Using the Grid: Computer-aided Grading of Neuroblastic Differentiation: Multi-resolution and Multi-classifieer Approach." in Challenges of Large Scale Applications in Distributed Environments (CLADE 2007). (6 2007).

2006

  • Gurcan, M.N.; Ernst R.; Oto, A.; Worrell, S; Hoffmeister, J.W.; Rogers, S. "Measurement of Colonic Polyp Size From Virtual Colonoscopic Studies: Comparison of Manual and Automated Methods." in SPIE Medical Imaging. (2 2006).

2005

  • Gurcan, M.N.; Stein, A.; Hoffmeister, J.W. "Polyp Size Measurements: Comparison of Size Estimation Methods for Axial Supine and Prone Views." in International Symposium on Virtual Colonoscopy. (10 2005).

2004

  • Gurcan, M.N.; Hardie, R.C.; Allen, B.H.; Rogers, S.K.; Dozier, D.E.; Burns, R.V.; Hoffmeister, J.W. "Automated Nodule Volume Estimation from CT Images: Minimax-Based Estimation." in PACS 2004. (1 2004).

2002

  • Sahiner, B.; Gurcan, M.N.; Chan, H.P.;Hadkiiski, L.M.;Petrick, N.; Helvie, M.A. "The Use of Joint Two-View Information for Computerized Lesion Detection on Mammograms: Improvement of Microcalcification Detection Accuracy." in Proceedings of SPIE Medical Imaging 2002. (1 2002).
  • Hadjiiski, L.M.; Chan, H.P.; Sahiner, B.; Petrick, N.; Helvie, M.A.; Roubidoux, M.; Gurcan, M.N. "Computer-Aided Characterization of Malignant and Benign Microcalcification Clusters Based on the Analysis of Temporal Change of Mammographic Features." in Proceedings of SPIE Medical Imaging 2002. (1 2002).

2001

  • Hadjiiski, L.; Sahiner, B.; Chan, H-P.; Petrick, N.; Helvie, M.A.; Gurcan, M.N. "Analysis of Temporal Change of Mamographic Features: Computer-Aided Classification of Malignant and Benign Breast Masses." in SPIE Medical Imaging. (1 2001).
  • Gurcan, M.N.; Petrick, N.; Sahiner, B.; Chan, H-P.; Cascade, P.N.; Kazerooni, EA; Hadjiiski, L.M.; "Computyerized Lung Nodule Detection on Thoracic CT Images: Combined Rule-based and Sattistical Classifier for False Positivie Reduction." in SPIE Medical Imaging 2001. (1 2001).

2000

  • Chan, H-P.; Hadjiiski, L.; Petrick, N.; Helvie, M.A.; Sahiner, B.; Paramagul, C.; Gurcan, M.N.; Lo, S-C.B.; Freeman, M.T; Dorman, DD; Berbaum, KS "Pilot Clinical Study of a Computer-aided Diagnostic Workstation for Mammography." in Era of Hope: Department of Defense Breast Cancer Research Program Meeting. (1 2000).
  • Gurcan, M.N.; Sahiner, B.; Chan, H-P.; Hadjiiski, L.; Petrick, N. "Optimal Selection of Neural Network Architecture for CAD Using Simulated Annealing." in 22nd Annual International Conference of theIEEE Engineering in Medicine and Biology Society. (1 2000).

1999

  • Gurcan, M.N.; Yardimci, Y.; Cetin, A.E. "Influence Function Based Gaussianity Tests for Detection of Microcalcifications in Mammogram Images,." in IEEE International Conference on Image Processing (ICIP'99). (1 1999).

1997

  • Gurcan, M.N.; Yardimci, Y.; Cetin, A.E.; Ansari, R "Detection of Microcalcifications in Mammograms Using Nonlinear Subband Decomposition and Outlier Labeling." in Proceedings of SPIE Visual Commincations and Image Processing Conference. (1 1997).

Patents

  • Gurcan, MN; Gordillo G; Sen S. "System and method for segmentation and automated measurement of chronic wound images."
  • Gurcan, MN; Abas F; Lozanski G. "Virtual Image Generator of Immunohistochemical Stained Tissue Sections."
  • Gurcan, MN; Hardie, RC; Rogers, SK. "Shape Estimates and Temporal Registration of Lesions and Nodules." Patent number: 7,486,812
  • Gurcan, MN. "Computer-aided Detection Methods in Volumetric Imagery." Patent number: 7,236,620