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Stephen Lee

  • Associate Professor, Biomedical Engineering
  • 317 Bevis Hall
    1080 Carmack Road
    Columbus, OH 43210
  • 614-688-5447

Honors

  • 2013

    Lumley Interdisciplinary Research Award. .

  • 2012

    Poster Award. .

  • 2009

    Poster Award:Fabrication and characterization of novel oxygen sensing implants for in vivo oximetry. Gurugahan Meenakshisundaram, S.C.Lee. P. Kuppusamy. .

  • 2007

    Poster Award Biomedical Engineering Department Ohio State University: Mark Elias, Xuejin Wen, Samit Gupta, John Shapiro, Matt Keener, Wu Lu and Leonard Brillson, S. C. Lee. Characterization of biologically modified field effect transistors..

  • 2007

    Herman R. Weed Award for Excellence in Teaching. .

  • 2006

    Scientist Guest of Honor Marcon 41.

  • 2003

    Honoree, Sphinx Senior Class Honorary, College of Engineering, Ohio State University.

  • 2003

    1st place winner (tie) Denman Undergraduate Research Forum. Ohio State University, Columbus, OH. B. Cipriani, P. Barnes, S. C. Lee and L. Brillson.

  • 2003

    Order of the Engineer.

  • 2003

    1st place winner (tie) Denman Undergraduate Research Forum. Ohio State University, Columbus, OH. A. Browne, M. Ferrari and S. C. Lee.

  • 1985

    Sigma Xi, The Scientific Research Society.

  • 1978

    Graduation with Honors, St. Ambrose College, Davenport, Iowa.

  • 1974-1978

    Quad City Scholarship, St. Ambrose College, Davenport, Iowa.

Edited Books

2001

  • 2001. "Biologic nanotechnology theme issue, Biomedical Microdevices and Biomems and Biomedical Nanotechnology." unstated: unstated.

1998

  • 1998. "Biological molecules in nanotechnology: the convergence of biotechnology, polymer chemistry and materials science." Southborough: IBC Press.

Chapters

2010

  • S.C. Lee and B. Bhushan. 2010. "Biological molecules in therapeutic nanodevices." In The Springer Handbook of Nanotechnology, edited by B. Bhushan, 453 - 484. Heidelberg: Springer-Verlag.

2007

  • S. C. Lee, M. Reugsegger, P. D. Barnes, B. R. Smith, M. Ferrari. 2007. "Therapeutic nanodevices." In The Springer Handbook of Nanotechnology, edited by B. Bhushan, Heidelberg: Springer-Verlag.

2006

  • S. C. Lee*, M. Reugsegger, P. D. Barnes, B. R. Smith, M. Ferrari. 2006. "Nanodevices in biomedical applications." In “BioMEMS and biomedical nanotechnology Volume 1: Prospectus, biological and biomedical nanotechnology, edited by A. P. Lee and L. J. Lee, 461 - 504. Heidelberg: Springer-Verlag.

2004

  • S. C. Lee, M. Reugsegger, M. Ferrari. 2004. "Biomolecules and nanodevices." In The Encyclopedia of Nanoscience and Nanotechnology, edited by H. S. Nalwa, 309 - 327. Stevenson Ranch: American Scientific Publishers.
  • S. C. Lee, M. Reugsegger, P. D. Barnes, B. R. Smith, M. Ferrari. 2004. "Therapeutic nanodevices." In The Springer Handbook of Nanotechnology, edited by B. Bhushan, 279 - 322. Heidelberg: Springer-Verlag.
  • S. C. Lee and K. D. Bhalerao. 2004. "Systems Design and Biological Nanodevices." In CD of BioMEMS and Nanotech World, Newton: unstated.

2002

  • S. C. Lee, R. Parthasarathy, K. Botwin, D. Kunneman, E. Rowold, G. Lange, J. Zobel, T. Beck, T. Miller and C. F. Voliva. 2002. "Humeral immune responses to polymeric nanomaterials." In Functional Condensation Polymers, edited by C. Carraher and G. Swift, 31 - 41. New York: Kluwer Publishers.

2001

  • S. C. Lee. 2001. "Dendrimers in nanobiological devices." In Dendrimers and other Dendritic Polymers, edited by Donald Tomalia & Jean Frechet, 548 - 557. London: John Wiley & Co.
  • S. C. Lee, R. Parthasarathy, T. Duffin, K. Botwin T. Beck, G. Lange, J. Zobel T. Beck, R. Jansson, D. Kunneman, E. Rowold and C. F. Voliva. 2001. "Antibodies to PAMAM dendrimers: Reagents for immune detection, assembly and patterning of dendrimers.." In Dendrimers and other Dendritic Polymers., edited by Donald Tomalia & Jean Frechet, 559 - 566. London: John Wiley & Co.

1998

  • S. C. Lee. 1998. "How molecular biologists can wind up organizing nanotechnology meetings." In Biological molecules in nanotechnology: the convergence of biotechnology, polymer chemistry and materials science, edited by S. C. Lee, & L. Savage, iv - Southborough: IBC Press.
  • S. C. Lee. 1998. "Engineering the protein components of nanobiological devices." In Biological molecules in nanotechnology: the convergence of biotechnology, polymer chemistry and materials science, edited by S. C. Lee, & L. Savage, 67 - 74. Southborough: IBC Press.
  • S. C. Lee. 1998. "The nanobiological strategy for construction of nanodevices." In Biological molecules in nanotechnology: the convergence of biotechnology, polymer chemistry and materials science, edited by S. C. Lee, & L. Savage, Southborough: IBC Press.

1988

  • S. C. Lee, S. R. Grant and S. N. Cohen. 1988. "SLP1 genes and sites involved in the integration of the element into the genome of Streptomyces lividans." In Biology of Actinomycetes '88, edited by Y. Okami, T. Beppu and H. Ogawara, Tokyo: Japan Scientific Societies Press.

Journal Articles

2013

  • Ramesh A, Ren F, Berger PR, Casal P, Theiss A, Gupta S, Lee SC, 2013, "Towards in vivo biosensors for low-cost protein sensing." Electronics Letters 49, 450 - 451.

2012

  • Casal P, Wen X, Gupta S, Nicholson T, Theiss A, Wang Y, Brillson L, Lu W, Lee SC, 2012, "ImmunoHFET feasibility in physiological salt environments." Journal of the Royal Society A 370, 2474 - 2488.

2011

  • Patricia Casal, Xuejin Wen, Samit Gupta, Theodore Nicholson, Andrew Theiss, Yuji Wang, Leonard Brillson, Wu Lu, and Stephen C. Lee., 2011, "ImmunoHFET operation in physiological salt environments." Journal of the Royal Society
  • Xuejin Wen, Samit Gupta, Yuji Wang, Theodore R. Nicholson III, Stephen C. Lee, and Wu Lu, 2011, High sensitivity AlGaN/GaN field effect transistor protein sensors operated in the sub-threshold regime by a control gate electrode. Virtual Journal of Biological Physics Rese 22, no. 3, 00 - 00.
  • Gupta,Samit,K; Wu,Hao-Hsuan; Kwak,Kwang,J; Casal,Patricia; Nicholson,Theodore,R; Wen,Xuejin; Anisha,R; Bhushan,Bharat; Berger,Paul,R; Lu,Wu; Brillson,Leonard,J; Lee,Stephen,Craig, 2011, "Interfacial design and structure of protein/polymer films on oxidized AlGaN surfaces." JOURNAL OF PHYSICS D-APPLIED PHYSICS 44, no. 3, 034010 -
  • Wen,Xuejin; Schuette,Michael,L; Gupta,Samit,Kumar; Nicholson,Theodore,R; Lee,Stephen,Craig; Lu,Wu, 2011, "Improved Sensitivity of AlGaN/GaN Field Effect Transistor Biosensors by Optimized Surface Functionalization." IEEE SENSORS JOURNAL 11, no. 8, 1726 - 1735.
  • Hao-Hsuan Wu, Mitchell Rutkowski, Samit Gupta, Xuejin Wen, Theodore R. Nicholson III, Wu Lu, Stephen C. Lee, and Leonard J. Brillson., 2011, "Nanoscale Depth-Resolved surface properties of 3-aminopropyltriethoxysilane, 3-aminopropyldimethylethoxysilane, and plasma-oxidized AlGaN/GaN heterostructure for immuno-modified Field Effect Transistors." Journal of Vacuum Science
  • Xuejin Wen, Samit Gupta, Yuji Wang, Theodore R. Nicholson III, Stephen C. Lee, and Wu Lu., 2011, "High sensitivity AlGaN/GaN field effect transistor protein sensors operated in the sub-threshold regime by a control gate electrode." Applied Physics Letters 99,
  • Xuejin Wen, Michael L. Schuette, Samit Gupta, Theodore R. Nicholson III, Stephen C. Lee, and Wu Lu., 2011, "Improved sensitivity of AlGaN/GaN field effect transistor biosensors by optimized surface functionalization.." IEEE Sensor Journal
  • Wen,Xuejin; Gupta,Samit; Wang,Yuji; Nicholson,Theodore,R; Lee,Stephen,C; Lu,Wu, 2011, "High sensitivity AlGaN/GaN field effect transistor protein sensors operated in the subthreshold regime by a control gate electrode." APPLIED PHYSICS LETTERS 99, no. 4, 043701 -
  • Xuejin Wen, Samit Gupta, Yuji Wang, Theodore R. Nicholson III, Stephen C. Lee, and Wu Lu., 2011, "High sensitivity operation of AlGaN/GaN HFET protein sensors accomplished by bias to the sub-threshold response regime by a control gate electrode.." Applied Physics Letters
  • B. Bhushan*, D. R. Tokachichu, M. T. Keener and Stephen Craig Lee., 2011, "Morphology and adhesion of biomolecules on silicon-based surface. Acta Biomaterialia 1: 327-341. (Impact factor 2.132)." Acta Biomaterialia 1, 327 - 341.
  • Xuejin Wen, Samit Gupta, Theodore R. Nicholson III, Leonard Brillson, Stephen C. Lee, and Wu Lu., 2011, "AlGaN/GaN HFET biosensors working at sub-threshold regime for sensitivity enhancement.." Physica Status Solidi C. 8, 2489 - 2491.
  • B. Bhushan, D. R. Tokachichu, M. T. Keener and Stephen Craig Lee., 2011, "Nanoscale adhesion, friction and wear studies on silicon based surfaces.." Acta Biomaterialia 2, 39 - 49.
  • Stephen Craig Lee*, Mathew T. Keener, Dharma R. Tokachichu, B. Bhushan, P. D. Barnes, B. J. Cipriany, M. Gao and L. J. Brillson., 2011, "Protein binding on thermally grown silicon dioxide." Journal of Vacuum Science and Technology B 23: 1856-1865. (Impact factor 1.664) 23, 1856 - 1865..

2010

  • S.C. Lee, 2010, "Implications of available design space for identification of non-immunogenic protein therapeutics." BIOMEDICAL MICRODEVICES 12, no. 2, 283 - 286.
  • Pandian,Ramasamy,P; Meenakshisundaram,Guruguhan; Bratasz,Anna; Eteshola,Edward; Lee,Stephen,C; Kuppusamy,Periannan, 2010, "An implantable Teflon chip holding lithium naphthalocyanine microcrystals for secure, safe, and repeated measurements of pO(2) in tissues." BIOMEDICAL MICRODEVICES 12, no. 3, 381 - 387.
  • R. P. Pandian, G. Meenakshisundaram, A. Bratasz, E. Eteshola, S. C. Lee and P. Kuppusamy., 2010, "An implantable Teflon chip holding lithium napthalocyanine microcrystals for secure, safe and repeated measurements of pO2 in tissues." Biomedical Microdevices 12, 381 - 387.
  • G. Meenakshisundarum, E. Eteshola, A. Blank, S. C. Lee, P. Kuppusamy., 2010, "A molecular paramagnetic spin-doped biopolymeric oxygen sensor.." Biosensors and Bioelectronics 25, 2283 - 2289.
  • Lee,Yvonne; Ferrari,Giacomo; Lee,Stephen,Craig, 2010, "Estimating design space available for polyepitopes through consideration of major histocompatibility complex binding motifs." BIOMEDICAL MICRODEVICES 12, no. 2, 207 - 222.
  • S. Gupta, H.-H. Wu,, K. J. Kwak, P. Casal, T. R. Nicholson III, X. Wen, A. Ramesh, B. Bhushan, P. R. Berger, Wu Lu, L. J. Brillson, Stephen Craig Lee., 2010, "Structures and tribological properties of protein/polymer films on oxidized AlGaN.." Journal of Applied Physics D. 44, 034010 -
  • S. Gupta, H.-H. Wu, K.J. Kwak, P. Casal, T.R. Nicholson III, X. Wen, A. Ramesh, B. Bhushan, P.R. Berger, W. Lu, L.J. Brillson, S.C. Lee, 2010, "Structures and tribological properties of protein/polymer films on oxidized AlGaN." Journal of Applied Physics D 44, 034010 -
  • T. R. Nicholson III, S. Gupta, X. Wen, H.-H. Wu, A. Ramish, P. Casal, K. J. Kwak, B. Bhushan, P. R. Berger, W. Lu, L. J. Brillson, Stephen Craig Lee., 2010, "Rational enhancement of nanobio-technological device function illustrated by partial optimization of a protein sensing field effect transistor." Proc. IMechE, Part N: J. Nanoengineering and Nanosystems 223, 149 - 163.
  • Stephen Craig Lee, 2010, "Implications of available design space for identification of non-immunogenic therapeutic proteins.." Biomedical Microdevices 12, 283 - 286.
  • G. Meenakshisundaram, E. Eteshola, A. Blank, S.C. Lee, P. Kuppusamy, 2010, "A molecular paramagnetic spin-doped biopolymeric oxygen sensor." BIOSENSORS & BIOELECTRONICS 25, no. 10, 2283 - 2289.
  • Meenakshisundaram,Guruguhan; Pandian,Ramasamy,P; Eteshola,Edward; Lee,Stephen,C; Kuppusamy,Periannan, 2010, "A paramagnetic implant containing lithium naphthalocyanine microcrystals for high-resolution biological oximetry." JOURNAL OF MAGNETIC RESONANCE 203, no. 1, 185 - 189.
  • Guruguhan Meenakshisundaram, Ramasamy P. Pandian, Edward Eteshola, Stephen C. Lee and Periannan Kuppusamy., 2010, "A paramagnetic implant containing lithium napthalocyanine microcrystals for high-resolution biological oximetry.." Journal of Magnetic Resonance 203, 185 - 189.
  • Y. Lee and G. Ferrari, and Stephen Craig Lee., 2010, "Estimating available design space for polyepitopes through ab initio consideration of Major Histocompatibility Complex class I and class II binding motifs.." Biomedical Microdevices 12, 207 - 222.

2009

  • B. Bhushan, K. J. Kwak, S. Gupta and Stephen C. Lee., 2009, "Nanoscale adhesion, friction and wear studies of biomolecules on polymer-coated silica and alumina based surfaces.." Journal of the Royal Society: Interface 6, 719 - 733.
  • Nijdam,A,Jasper; Nicholson,Theodore,R; Shapiro,John,P; Smith,Bryan,R; Heverhagen,Johannes,T; Schmalbrock,Petra; Knopp,Michael,V; Kebbel,Andrew; Wang,David; Lee,Stephen,C, 2009, "Nanoparticulate Iron Oxide Contrast Agents for Untargeted and Targeted Cardiovascular Magnetic Resonance Imaging." CURRENT NANOSCIENCE 5, no. 1, 88 - 102.
  • Eteshola,Edward; Pandian,Ramasamy,P; Lee,Stephen,C; Kuppusamy,Periannan, 2009, "Polymer coating of paramagnetic particulates for in vivo oxygen-sensing applications." BIOMEDICAL MICRODEVICES 11, no. 2, 379 - 387.
  • Meenakshisundaram,Guruguhan; Eteshola,Edward; Pandian,Ramasamy,P; Bratasz,Anna; Selvendiran,Karuppaiyah; Lee,Stephen,C; Krishna,Murali,C; Swartz,Harold,M; Kuppusamy,Periannan, 2009, "Oxygen sensitivity and biocompatibility of an implantable paramagnetic probe for repeated measurements of tissue oxygenation." BIOMEDICAL MICRODEVICES 11, no. 4, 817 - 826.
  • Meenakshisundaram,Guruguhan; Eteshola,Edward; Pandian,Ramasamy,P; Bratasz,Anna; Lee,Stephen,C; Kuppusamy,Periannan, 2009, "Fabrication and physical evaluation of a polymer-encapsulated paramagnetic probe for biomedical oximetry." BIOMEDICAL MICRODEVICES 11, no. 4, 773 - 782.
  • Bhushan,Bharat; Kwak,Kwang,Joo; Gupta,Samit; Lee,Stephen,C, 2009, "Nanoscale adhesion, friction and wear studies of biomolecules on silane polymer-coated silica and alumina-based surfaces." JOURNAL OF THE ROYAL SOCIETY INTERFACE 6, no. 37, 719 - 733.
  • Edward Eteshola, Ramasamy Pandian, Stephen C. Lee, and Periannen Kuppusamy., 2009, "Polymer coating of paramagnetic particles for in vivo oxygen-sensing.." Biomedical Microdevices 11, 379 - 387.
  • Guruguhan Meenakshisundaram, Edward Eteshola, Ramasamy P. Pandian, Anna Bratasz, Karuppaiyah Selvendiran, Stephen C. Lee, Murali C. Krishna, Harold M. Swartz, and Periannan Kuppusamy, 2009, "Oxygen sensitivity and biocompatibility of an implantable paramagnetic probe for repeated measurements of tissue oxygenation." Biomedical Microdevices 11, 817 - 826.
  • A. Jaspar Nijdam, Theodore R. Nicholson III, J. Shapiro, Bryan R. Smith, Johannes T. Heverhagen, Petra Schmalbrock, Michael V. Knopp, Andrew Kebbel, David Wang and Stephen C. Lee, 2009, "Biochemically targeted nanoparticulate contrast agents for magnetic resonance imaging and diagnosis of cardiovascular disease.." Current Nanoscience 5, 88 - 102.
  • Guruguhan Meenakshisundaram, Edward Eteshola, Anna Bratasz, Ramasamy P. Pandian, Stephen C. Lee and Periannan Kuppusamy, 2009, "Fabrication and physical evaluation of a polymer-encapsulated particulate electron paramagnetic resonance (EPR) probe for oxygen-sensing applications." Biomedical Microdevices 11, 773 - 782.

2008

  • Gupta,Samit; Elias,Mark; Wen,Xuejin; Shapiro,John; Brillson,Leonard; Lu,Wu; Lee,Stephen,Craig, 2008, "Detection of clinically relevant levels of protein analyte under physiologic buffer using planar field effect transistors." BIOSENSORS & BIOELECTRONICS 24, no. 4, 505 - 511.
  • S. Gupta, M. Elias, X. Wen, J. Shapiro, L. Brillson, W. Lu, and Stephen C. Lee, 2008, "Detection of clinically relevant levels of biological analyte under physiologic buffer using planar field effect transistors." Biosensors and Bioelectronics 24, 505 - 511..
  • Edward Eteshola, Mathew T. Keener, Mark A. Elias, John Shapiro, Leonard J. Brillson, Bharat Bhushan, and Stephen Craig Lee. 2008. Engineering functional protein interfaces for immunologically modified field effect trasistors (immunoFETs) by molecular genetic means. Journal of The Royal Society: Interface 5: 123-127. (Impact factor 2.984), 2008, "Engineering functional protein interfaces for immunologically modified field effect trasistors (immunoFETs) by molecular genetic means." Journal of The Royal Society: Interface 5, 123 - 127.
  • Eteshola,Edward; Keener,Matthew,T; Elias,Mark; Shapiro,John; Brillson,Leonard,J; Bhushan,Bharat; Lee,Stephen,Craig, 2008, "Engineering functional protein interfaces for immunologically modified field effect transistor (ImmunoFET) by molecular genetic means." JOURNAL OF THE ROYAL SOCIETY INTERFACE 5, no. 18, 123 - 127.
  • B. R. Smith, et al., 2008, "ERRATUM: Magnetic Resonance Imaging of atherosclerosis in vivo using biochemically targeted ultrasmall superparamagnetic iron oxide particles (SPIONs).." Biomedical Microdevices 10, 129 - 130.

2007

  • K. Bhalerao, S. C. Lee, W. O. Soboyejo, and A. B. O. Soboyejo., 2007, "A folic acid-based functionalized surface for biosensor systems. Journal of Materials Science: Materials in Medicine 18: 3-8 (Impact factor 0.864).." Journal of Materials Science: Materials in Medicine 18, 3 - 8.
  • Smith,Bryan,R; Heverhagen,Johannes; Knopp,Michael; Schmalbrock,Petra; Shapiro,John; Shiomi,Masashi; Moldovan,Nicanor,I; Ferrari,Mauro; Lee,Stephen,C, 2007, "Localization to atherosclerotic plaque and biodistribution of biochemically derivatized superparamagnetic iron oxide nanoparticles (SPIONs) contrast particles for magnetic resonance imaging (MRI)." BIOMEDICAL MICRODEVICES 9, no. 5, 719 - 727.
  • Bryan R. Smith, Johannes Heverhagen, Michael Knopp, Petra Schmalbrock, John Shapiro, Masashi Shiomi, Nicanor Moldovan; Mauro Ferrari and Stephen C. Lee, 2007, "Magnetic Resonance Imaging of atherosclerosis in vivo using biochemically targeted ultrasmall superparamagnetic iron oxide particles (SPIONs)." Biomedical Microdevices 9, 719 - 728.

2006

  • Bhushan,B; Tokachichu,D,R; Keener,M,T; Lee,S,C, 2006, "Nanoscale adhesion, friction and wear studies of biomolecules on silicon based surfaces." ACTA BIOMATERIALIA 2, no. 1, 39 - 49.
  • E. Eteshola, C. D. Van Valkenburgh, S. Merlin, E. Rowold, J. Adams, R. Ibdah, L. E. Pegg, A.Donelly, E. Rowold, Jon Klover and S. C. Lee, 2006, "Screening of a library of circularly permuted proteins on phage to manipulate protein topography.." Proc. IMechE, Part N: J. Nanoengineering and Nanosystems 219(N2), 45 - 55.

2005

  • Eteshola,E; BRILLSON,L,J; Lee,S,C, 2005, "Selection and characteristics of peptides that bind thermally grown silicon dioxide films." BIOMOLECULAR ENGINEERING 22, no. 5-6, 201 - 204.
  • B. Bhushan*, D. R. Tokachichu, M. T. Keener and Stephen Craig Lee, 2005, Morphology and adhesion of biomolecules on silicon-based surface. Virtual Journal of Biological Physics Research: Protein Conformational Dynamics/Folding Section 10, no. 4, 00 - 00.
  • S. C. Lee*, R. Parthasarathy, K. Botwin, D. Kunneman, E. Rowold, G. Lange, J. Zobel, T. Beck, T. Miller, W. Hood, J. Monahan R. Jansson, J. P. McKearn and C. F. Voliva., 2005, "Biochemical and immunological properties of cytokines conjugated to dendritic polymers." Biomedical Microdevices 6, 191 - 201.
  • P. Decuzzi S. C. Lee, B. Bhushan and M. Ferrari., 2005, "A theoretical model for the margination of particles within blood vessels." Annals of Biomedical Engineering 33, 179 - 190.
  • B. Bhushan*, D. R. Tokachichu, M. T. Keener and Stephen Craig Lee, 2005, Morphology and adhesion of biomolecules on silicon-based surface. Virtual Journal of Nanoscale Science & Technology: Supramolecular and Biochemical Assembly Section 12, no. 9, 00 - 00.
  • E. Eteshola, Leonard Brillson and Stephen Craig Lee., 2005, "Selection and characteristics of peptides that bind thermally grown silicon dioxide films.." Biomolecular Engineering 22: 202-204 (Impact factor 1.612), 202 - 204.
  • Lee,S,C; Keener,M,T; Tokachichu,D,R; BHUSHAN,B; Barnes,P,D; Cipriany,B,R; Gao,M; BRILLSON,L,J, 2005, "Protein binding on thermally grown silicon dioxide." JOURNAL OF VACUUM SCIENCE & TECHNOLOGY B 23, no. 5, 1856 - 1865.
  • Stephen Craig Lee*, Mathew T. Keener, Dharma R. Tokachichu, B. Bhushan, P. D. Barnes, B. J. Cipriany, M. Gao and L. J. Brillson, 2005, "Protein binding on thermally grown silicon dioxide." Virtual Journal of Biological Physics Research: Instrumentation Development Section 10, no. 7, 00 - 00.
  • Stephen Craig Lee*, Mathew T. Keener, Dharma R. Tokachichu, B. Bhushan, P. D. Barnes, B. J. Cipriany, M. Gao and L. J. Brillson, 2005, "Protein binding on thermally grown silicon dioxide." Virtual Journal of Nanoscale Science & Technology: Supramolecular and Biochemical Assembly Section 12, no. 15, 00 - 00.
  • K. D. Bhalerao, E. Eteshola, M. Keener and Stephen Craig Lee, 2005, "Nanodevice design through the functional abstraction of biological macromolecules." Applied Physics Letters 87, 143902 - 143904.
  • J. H. Sakamoto, B. R. Smith, B. Xie, S. I Rokhlin, S. C. Lee, M. Ferrari., 2005, "The Molecular Analysis of Breast Cancer Utilizing Targeted Nanoparticle Ultrasound Contrast Agents.." Technology in Cancer Research and Treatment 4, 627 - 636.

2004

  • P. Decuzzi, S. C. Lee, M. Decuzzi and M. Ferrari, 2004, "Adhesion of micro-fabricated particles on vascular endothelium: a parametric analysis.." Annals of Biomedical Engineering 32, 793 - 802.
  • S. C. Lee*, K. Bhalerao, M. Ferrari, 2004, "Object oriented design tools for supramolecular devices and biomedical nanotechnology." Annals of the New York Academy of Science 1013, 110 - 123.
  • B. R. Smith, A. J. Nijdam, M. C. Cheng, X. Liu, S. C. Lee and M. Ferrari, 2004, "Particulate nanopourous silicon: a biomedical perspective.." Materials Technology 19, 16 - 20.
  • Smith,B,R; Nijdam,A,J; Cheng,M,C; Liu,X; Lee,S,C, 2004, "A biological perspective of particulate nanoporous silicon." MATERIALS TECHNOLOGY 19, no. 1, 16 - 20.
  • S. A Ross*, P. R. Srinivas, A. J. Clifford, S. C. Lee, M. A. Philbert and R. L. Hetich, 2004, "New technologies for nutrition research." Journal of Nutrition 134, 681 - 685.

2003

  • D. B. Buxton*, S. C. Lee, S. A. Wickline and M. Ferrari, 2003, "Recommendations of the National Heart, Lung, and Blood Institute Nanotechnology Working Group." Circulation 108, 2737 - 2742.
  • B.S.M. Lee, S. C. Lee and L. S. Holliday, 2003, "Biochemistry of mechanoenzymes: Biological motors for nanotechnology." Biomedical Microdevices: Biomems and Biomedical Nanotechnology 5, 269 - 280.

2002

  • V. T. Granik, B. R. Smith, S. C. Lee and Mauro Ferrari, 2002, "Osmotic Pressures for Binary Solutions of Non-electrolytes.." Biomedical Microdevices: Biomems and Biomedical Nanotechnology 4, 309 - 321.

2001

  • S. C. Lee, 2001, "What's in a name…apropos MPO?." Leukemia 15, 1147 -
  • S. C. Lee, James R. Baker, Jr. and Miqin Zhang, 2001, "Interfaces." Biomedical Microdevices: Biomems and Biomedical Nanotechnology 3, 5 - 6.
  • S. C. Lee*, R. Parthasarathy, T. Duffin, K. Botwin, T. Beck, G. Lange, J. Zobel D. Kunneman, E. Rowold and C. F. Voliva., 2001, "Recognition properties of antibodies to PAMAM dendrimers and their use in immune detection of dendrimers.." Biomedical Microdevices: Biomems and Biomedical Nanotechnology 3, 51 - 57.
  • S. C. Lee*, R. Ibdah, C. VanValkenburgh, E. Rowold, A. Donnelly, A. Abegg, J. Klover, S. Merlin and J. McKearn, 2001, "Phage display mutagenesis of the chimeric dual cytokine receptor agonist myelopoietin." Leukemia 15, 1277 - 1285.

1999

  • S. C. Lee*, R. Parthasarathy and K. Botwin, 1999, "Protein-polymer conjugates: synthesis of simple nanobiotechnological devices." Polymer Preprints 40, 449 - 450.

1998

  • S. C. Lee, 1998, "Biotechnology for nanotechnology." Trends in Biotechnology 16, 239 - 240.

1997

  • Merlin S; Rowold E; Abegg A; Berglund C; Klover J; Staten N; McKearn JP; Lee SC, 1997, "Phage presentation and affinity selection of a deletion mutant of human interleukin-3.." Applied Biochemistry And Biotechnology 67, no. 3, 199 -

1996

  • De Ciechi PA; Devine CS; Lee SC; Howard SC; Olins PO; Caparon MH, 1996, "Utilization of multiple phage display libraries for the identification of dissimilar peptide motifs that bind to a B7-1 monoclonal antibody.." Molecular Diversity 1, no. 2, 79 -
  • Caparon MH; De Ciechi PA; Devine CS; Olins PO; Lee SC, 1996, "Analysis of novel streptavidin-binding peptides, identified using a phage display library, shows that amino acids external to a perfectly conserved consensus sequence and to the presented peptides contribute to binding.." Molecular Diversity 1, no. 4, 241 -

1995

  • Weinberg RA; McWherter CA; Freeman SK; Wood DC; Gordon JI; Lee SC, 1995, "Genetic studies reveal that myristoylCoA:protein N-myristoyltransferase is an essential enzyme in Candida albicans.." Molecular Microbiology 16, no. 2, 241 -
  • Leusch MS; Lee SC; Olins PO, 1995, "A novel host-vector system for direct selection of recombinant baculoviruses (bacmids) in Escherichia coli.." Gene 160, no. 2, 191 -

1993

  • P. O. Olins and S. C. Lee, 1993, "Recent advances in heterologous gene expression in Escherichia coli.." Current Opinion in Biotechnology 4, 520 - 525.
  • Brasch MA; Pettis GS; Lee SC; Cohen SN, 1993, "Localization and nucleotide sequences of genes mediating site-specific recombination of the SLP1 element in Streptomyces lividans.." Journal Of Bacteriology 175, no. 10, 3067 -
  • Luckow VA; Lee SC; Barry GF; Olins PO, 1993, "Efficient generation of infectious recombinant baculoviruses by site-specific transposon-mediated insertion of foreign genes into a baculovirus genome propagated in Escherichia coli.." Journal Of Virology 67, no. 8, 4566 -

1992

  • Lee SC; Olins PO, 1992, "Effect of overproduction of heat shock chaperones GroESL and DnaK on human procollagenase production in Escherichia coli.." The Journal Of Biological Chemistry 267, no. 5, 2849 -

1989

  • Grant SR; Lee SC; Kendall K; Cohen SN, 1989, "Identification and characterization of a locus inhibiting extrachromosomal maintenance of the Streptomyces plasmid SLP1.." Molecular & General Genetics: MGG 217, no. 2-3, 324 -

1988

  • Clabots C; Lee S; Gerding D; Mulligan M; Kwok R; Schaberg D; Fekety R; Peterson L, 1988, "Clostridium difficile plasmid isolation as an epidemiologic tool.." European Journal Of Clinical Microbiology & Infectious Diseases: Official Publication Of The European Society Of Clinical Microbiology 7, no. 2, 312 -
  • Lee SC; Omer CA; Brasch MA; Cohen SN, 1988, "Analysis of recombination occurring at SLP1 att sites.." Journal Of Bacteriology 170, no. 12, 5806 -

1987

  • Lee,S,C; Stein,D,S; Cohen,S,N, 1987, "Bulk capreomycin sulfate can be used to select for Streptomyces bearing the viomycin phosphotransferase (vph) gene." Trends in Genetics 3, 240 -
  • S. C. Lee*, P. P. Cleary and D. N. Gerding, 1987, "More than one DNA sequence encodes the 2"-0 Adenylyltransferase phenotype." Antimicrobial Agents and Chemotherapy 31, 667 - 670.

1986

  • S. C. Lee*, D. N. Gerding and P. P. Cleary, 1986, "Hospital distribution, persistence and reintroduction of related gentamicin R plasmids." Antimicrobial Agents and Chemotherapy 29, 654 - 659.

1984

  • S. C. Lee*, D. N. Gerding and P. P. Cleary, 1984, "Plasmid macro-evolution in a nosocomial environment: demonstration of a persistent molecular polymorphism and construction of a cladistic phylogeny on the basis of restriction data." Molecular & General Genetics 194, 173 - 178.

Presentations

  • "Department of Biomedical Engineering, University of Iowa, Iowa City." 2008,
  • "Conference on New Trends in Streptomyces Research, Taipei, Taiwan." 1988,
  • "7th International Symposium on Biology of Actinomycetes, Tokyo, Japan." 1988,
  • "Project Manager Seminar, NASA, Arlington, VA." 1999,
  • "DARPA/DSRC Study on Nanomaterials and Technologies, Arlington, VA." 1999,
  • "ACS Symposium on Nanostructured and Nanopatterned Materials,Anaheim, CA." 1999,
  • "Eveready Ideation Symposium, Cleveland, OH." 2000,
  • "Department of Physics, Case Western Reserve University, Cleveland, OH." 2000,
  • "Department of Molecular and Cellular Biochemistry, Ohio State University,Columbus, OH." 2000,
  • "Northrop Grumman TASC Division, Chantilly VA." 2001,
  • "4th Annual IMAT Investigator Meeting, San Diego, CA (Keynote lecture)." 2003,
  • "2nd International Congress of Nanobiotechnology & Nanomedicine of the International Association for Nanotechnology, San Francisco." 2007,
  • "IBC 2nd International Conference on Display Technology, Boston, MAIBC 2nd International Conference on Display Technology, Boston, MA." 1997,
  • "NSF-IC Approaches to combat Terrorism FY 2003 PI Workshop, Arlington VA." 2004,
  • "5th Annual IMAT Investigator Meeting, San Diego, CA." 2004,
  • "Nephrology Fellows Conference, Ohio State University, Columbus, OHTokyo, Japan." 2004,
  • "Context 17, Columbus, OH." 2004,
  • "Unither Nanomedical & Telemedical Technology Conference, Magog Quebec." 2010,
  • "Thirty years of cloning: A Symposium Honoring Stanley N. Cohen." 2010, Presented at Sponsored by Stanford University, Silverado, CA,
  • "Great Lakes Transplant Immunology Foundation Symposium, Chicago, IL." 2010,
  • "Tulane University, Department of Cell and Molecular Biology, New Orleans,LA." 1993,
  • "School of Pharmacy, University of Wisconsin, Madison, WI." 2000,
  • "Immunogenicity Summit." 2010, Philadelphia,
  • "Dendrimer Workshop, National Institute of Standards, Washington, DC." 1998,
  • "Plenary Lecture, BioMEMS & Biomedical Nanotechnology, Columbus, OH." 2001,
  • "Noreascon 4, Boston, MATokyo, Japan." 2004,
  • "Materials Science Section, Nara Institute of Science and Technology, Nara,Japan." 1998,
  • "International Symposium on Nanotechnology and Biotechnology for FutureDevices, Nara Institute of Science and Technology, Nara, Japan." 1998,
  • "University of Michigan Center for Biologic Nanotechnology, Ann Arbor, MI." 1999,
  • "Workshop Leader, BioMEMS & Biomedical Nanotechnology, Columbus, OH." 2002,
  • "Tumor Biology Session Chair, BioMEMS & Biomedical Nanotechnology World, Columbus, OH." 2002,
  • "Sensors and Sensing Workshop, Science Applications International Corporation, San Diego, CA." 2002,
  • "Intell Early Disease Detection Symposium, San Francisco, CA." 2002,
  • "IWACOM Workshop on Computational Biomechanics and BionanosystemsTokyo, Japan." 2004,
  • "Department of Microsystems Technology, Ritsumeikan University, Shiga, JapanTokyo, Japan." 2004,
  • "Department of Mechanical Engineering, Osaka Institute of Technology, Osaka, Japan.Tokyo, Japan." 2004,
  • "University of Iowa, Department of Zoology, Iowa City, IA." 1984,
  • "Department of Biomedical Engineering, Washington University, St. Louis, MO." 2000,
  • "Nanotechnology at the Interface of Information Technology, Baton Rouge,LA." 2002,
  • "Wittenberg College Department of Physics." 2002,
  • "Department of Chemical Engineering Ohio State University." 2002,
  • "National Cancer Institute, Frederick, MD." 2003,
  • "Dorothy M. Davis Heart and Lung Research Institute Research in Progress Seminar." 2003,
  • "Stanford University, Department of Genetics, Stanford, CA." 1991,
  • "Center for Nanotechnology, University of Washington, Seattle, WA." 1998,
  • "Department of Chemistry, Washington University, St. Louis, MO." 1999,
  • "Central Society For Clinical Research Symposium on TherapeuticNanotechnology, Chicago, IL." 2000,
  • "Biomems & Biomedical Nanotechnology 2000, Columbus, OH." 2000,
  • "Biomedical Engineering Center, Ohio State University, Columbus, OH." 2004,
  • "Biotechnology in the 21st Century: a Symposium Honoring Stanley N. Cohen, Sponsored by Stanford University, Silverado, CA." 2005,
  • "Research Day, Ohio State University College of Dentistry, Columbus, OH(Keynote)." 2006,
  • "Stanford University Office of Technology Licensing, Stanford, CA." 1995,
  • "Department of Physics, Washington University, St. Louis, MO." 1998,
  • "ACS Symposium on Functional Condensation Polymers, San Diego, CA." 2001,
  • "Transplant Seminar, Department of Surgery, OSU Medical Center." 2003,
  • "Investigator’s meeting, USA-Africa International Materials Institute, Princeton, NJ." 2003,
  • "Cardiovascular Intervention Research Group, Davis Heart and Lung Research Institute, Columbus, OH." 2006,
  • "National Cancer Institute, National Institutes of Health, Bethesda, MD." 1989,
  • "Central Society For Clinical Research Symposium." 2000,
  • "Biomedical Engineering Center, Ohio State University, Columbus, OH." 2000,
  • "Nanospace 2001: Exploring Interdisciplinary Frontiers, Galveston, TX." 2001,
  • "Department of Physiology, Ohio State University, Columbus, OH." 2002,
  • "IBC 2nd International Conference on Molecular Nanotechnology (ConferenceChairperson), San Diego, CA." 1997,
  • "Biomedical Engineering Center, Ohio State University, Columbus, OH." 2001,
  • "New Technologies for Nutrition Research Symposium, Experimental Biology 2003 Annual Meeting (FASEB), San Diego, CA." 2003,
  • "Materials Research Society, San Francisco, CA." 2003,
  • "Center for Materials Research, OSU." 2003,
  • "BioMEMS & Biomedical Nanotechnology World 2004, Washington, DC (Keynote) Tokyo, Japan." 2004,
  • "Marcon 41, Columbus, OH." 2006,

Papers in Proceedings

2010

  • S. C. Lee. "Design space available for non-immunogenic proteins." in Immunogenicity Summit 2010 Conference Proceedings @ http://www.chiresourrce.com/imn-pdf-12-02/login.asp. Boston, (11 2010). 00 - 00.

2009

  • Gupta,Samit,K; Nicholson,Theodore,R; Theiss,Andy; Wen,Xuejin; Lu,Wu; Brillson,Leonard; Lee,Stephen,C "ANYL 256-Real-time, label-free detection of monokine induced by interferon gamma with an immunoFET under physiological salt." JOURNAL: "ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY." (8 2009). 00 - 00.

2007

  • Bhalerao,Kaustubh,D; Lee,Stephen,C; Soboyejo,Winston,O; Soboyejo,Alfred,BO "A folic acid-based functionalized surface for biosensor systems." JOURNAL: "JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE." in Annual Winter Meeting of the American-Society-Mechanical-Engineers. DORDRECHT, (1 2007). 3 - 8.

2005

  • Bhushan,B; Tokachichu,D,R; Keener,M,T; Lee,S,C "Morphology and adhesion of biomolecules on silicon based surfaces." JOURNAL: "ACTA BIOMATERIALIA." in Conference on Single Cell Mechanics. OXFORD, (5 2005). 327 - 341.

2004

  • Lee,S,C; Bhalerao,K; Ferrari,M "Object-oriented design tools for supramolecular devices and biomedical nanotechnology." JOURNAL: "COEVOLUTION OF HUMAN POTENTIAL AND CONVERGING TECHNOLOGIES." in NBIC Convergence 2003 Conference on Converging Technologies for Improving Human Performance. NEW YORK, (1 2004). 110 - 123.

2001

  • S. C. Lee*, R. Parthasarathy, K. Botwin, D. Kunneman, E. Rowold, G. Lange, J. Zobel, T. Beck, T. Miller and C. F. Voliva "Antibody responses to dendrimers: Strategies and implications." in Polymeric Materials: Science and Engineering Proceedings. (1 2001). 824 - 825.
  • Lee,S,C; Parthasarathy,R; Botwin,K; Kunneman,D; Rowold,E; Lange,G; Zobel,J; Beck,T; Duffin,T; Jansson,R; Voliva,C,F "Antibody responses to dendrimers: Strategies and implications.." JOURNAL: "ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY." (4 2001). U427 - U427.

2000

  • S. C. Lee "A biological nanodevice for drug delivery." in National Science and Technology Council. IWGN Workshop Report: Nanotechnology Research Directions. Baltimore, (1 2000).

1999

  • S. C. Lee. "A biological nanodevice for drug delivery." in National Science and Technology Council. IWGN Workshop Report: Nanotechnology Research Directions. Baltimore, (1 1999).

Patents

  • S. C. Lee, M. S. Leusch, V. A. Luckow and P. O. Olins. "Method of producing recombinant infectious baculoviruses in bacteria with bacmids and use of the recombinant baculoviruses in insect cell expression systems." Patent number: 5, 348, 886
  • Y. Feng, N. R. Staten, C. M. Baum, N. L. Summers, M. Caparon, S. C. Bauer, L. Zurfluh, J. P. McKearn, B. K. Klein, S. C. Lee, C. A. McWherter.. "Multi-functional hematopoeitic receptor agonists." Patent number: International Patent # WO 97/12985
  • Feng, Y., Staten, N. R., Baum, C. M.. Summers, N. L. Caparon, M. H., Bauer, S. C., Zurfluh, L., McKearn, J. P.;Klein, B. K. Lee, S. C., McWherter, C. A., Giri, J. G.. "Multi-functional chimeric hematopoietic receptor agonists." Patent number: 6, 066, 318
  • N. Summers and S. C. Lee. "A computational method to design polypeptides with controlled distributions of immunogenic epitopes."
  • S. Lee, P. Barnes and L. Brillson. "BioFET sensors for Biothreats."
  • Lee, Stephen C., Summers, Neena L.. "Controlling distribution of epitopes in polypeptide sequences." Patent number: U.S. Pat. Appl. Publ.
  • Barnes, Phillip D.; Brillson, Leonard; Lee, Stephen C.. "Detection of chemical and biological toxins in the air and in fluids.." Patent number: PCT Int. Application WO/2004/031721
  • S. C. Lee. "Protein engineering for biosensors: Engineering donor-acceptor distances.."
  • Smith, Bryan, N. Moldovan and S. Lee. "Compositions and methods for non-invasive, in vivo plaque imaging and targeting."
  • Stephen C. Lee, Samit Gupta, Wu Lu, Len Brillson. "Interfacial optimization of ImmunoFET sensor to enable analyte detection in complex sensing environments."
  • Stephen C. Lee. "Use of biochemically targeted MRI contrast agents to monitor anti-angiogenic therapies."
  • E. Eteshola, Leonard Brillson and Stephen Craig Lee. "Peptides that bind thermally grown silicon dioxide films and uses thereof.."
  • R. Parthasarathy and S. C. Lee. "Site specific conjugation/ligation of proteins to synthetic particles." Patent number: 6,485,718
  • Feng; Y.; Staten; N. R. (St. Louis, MO); Baum C., Summers; N. L.; Caparon; M.: Bauer; S. C.; Zurfluh; L.; McKearn; J. P.; Klein; B. K.; Lee; S. C.; McWherter; C. A.; Giri; J. G.. "Fused G-CSF and IL-3 proteins and uses thereof.." Patent number: 6,730,303
  • Kebbel, Andrew, J. Shapiro, S. C. Lee. "Development of cardiovascular nanodevices for the detection of vulnerable plaque."