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Jennifer Leight

  • Assistant Professor, Biomedical Engineering
  • 291 Bevis Hall
    1080 Carmack Road
    Columbus, OH 43210
  • 614-685-9147

About

Education

  • B.S., Tulane University, 2004
  • Ph.D., University of Pennsylvania, 2011

 

Key Honors and Distinctions

  • US Frontiers of Engineering Symposium Participant, National Academy of Engineering (2016)
  • Chair, Graduate Research Seminar – Signal Transduction by Engineered ECM Gordon Conference (2010)
  • National Science Foundation Graduate Research Fellowship (2005)

 

RESEARCH AREAS – Leight Lab for Engineering the Cancer Microenvironment [leightlab.engineering.osu.edu]

  • Polymers; Biomaterials; Molecular, cell and tissue engineering; Cancer

  • PUBLICATIONS

leightlab.engineering.osu.edu/publications

The Leight Lab focuses on the development and utilization of new tools to understand how the microenvironment is remodeled during tumorigenesis and how this remodeling impacts cancer cell function and response to treatment. Specifically, we use fluorogenic peptide biosensors in tunable 3D hydrogel platforms to investigate microenvironmental regulation of protease activity, cell viability, and migration. Applications for our technology are far reaching, not only for screening cancer therapeutics, but also in other contexts in which protease activity plays an important role, such as heart disease, arthritis, and tissue regeneration.