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Alan Litsky

  • Associate Professor, Biomedical Engineering
  • Associate Professor, Orthopaedics
  • 292 Bevis Hall
    1080 Carmack Road
    Columbus, OH 43210
  • 614-292-5238

About

EDUCATION

  • B.A., Princeton University, 1975
  • M.D., College of Physicians and Surgeons, Columbia University, 1979
  • Sc.D., Massachusetts Institute of Technology, 1988

 

Key Honors and Distinctions

  • Hertz Fellowship (1982-1988)
  • Elected Fellow - American Institute for Medical and Biological Engineering (2009)

 

RESEARCH AREAS – Orthopaedic BioMaterials Laboratory

  • Hard-Tissue Biomaterials
  • Endoprosthesis Fixation and Micromotion
  • Biomechanics of Fracture Repair
  • Orthopaedic / Dental / Veterinary Implant Evaluations

     Research in the Orthopaedic BioMaterials Laboratory focuses on the investigation of the mechanical properties of biomaterials for hard-tissue applications including biological musculoskeletal tissues and orthopaedic, dental, and veterinary devices.  Recent projects have included studies of shape-memory alloys for fracture fixation, a quantification of the micromotion between components of total hip arthroplasties, studies of the fatigue behavior of external fixators and dental prostheses, and testing a novel technique for securing mechanical devices to skeletal muscle which is being used for the development of a synthetic tendon.  Another project focused on gathering force-motion data of bone cutting tools which provided input to improve the haptic feedback of a surgical simulation system.  Clinically-driven projects have focused on fracture fixation techniques, intra-articular knee stresses, the mechanics of osteochondral plugs, ACL graft fixation, and stabilization systems for spinal fusion. 

 

  • PUBLICATIONS

   Bishop, J.Y., Roesch, M., Lewis, B.D., Jones, G.L., and Litsky, A.S.   A Biomechanical Comparison of Distal Clavicle Fracture Reconstructive Techniques.  Am. J. Orthop., 42(3):114-118, 2013.

   Agnew, A.M., Moorhouse, K., Kang, Y-S., Donnelly, B.R., Pfefferle, K., Manning, A.X., Litsky, A.S., Herriott, R., Abdel-Rasoul, M., and Bolte, J.H.  The Response of Pediatric Ribs to Quasi-static Loading: Mechanical Properties and Microstructure.  Annals of Biomed. Eng., 41(12):2501-2514, 2013.  

   Hettlich, B.F., Allen, M.J., Pascetta, D., Fosgate, G.T., and Litsky, A.S.  Biomechanical Comparison Between Bicortical Pin and Monocortical Screw/Polymethylmethacrylate Constructs in the Cadaveric Canine Cervical Vertebral Column.  Vet. Surg., 42:693-700, 2013.

   Williams, J., Elce, Y., and Litsky, A.  Comparison of Two Equine Transfixation Pin Casts and the Effects of Pin Removal.  Vet. Surg., 43(4):430-436, 2014.

   McClellan, N.R., Santschi, E.M., Hurcombe, D.A., and Litsky, A.S.  An Ex Vivo Model to Evaluate the Effect of Cyclical Adductory Forces on Maintenance of Arytenoid Abduction After Prosthetic Laryngoplasty Performed With and Without Mechanical Arytenoid Abduction.  Vet. Surg., 43(5):598-605, 2014.

   Hettlich, B.F., Allen, M.J., Gluckman, G.S., Fosgate, G.T., and Litsky, A.S.  Effect of an Intervertebral Disk Spacer on Stiffness after Monocortical Screw/Polymethylmethacrylate Fixation in Simulated and Cadaveric Canine Cervical Vertebral Columns.  Vet. Surg., 43(8):988-994, 2014.

   Bonilla, A.G., Williams, J.M., Litsky, A.S., and Santschi, E.  Ex-vivo equine medial tibial plateau contact pressure with an intact medial femoral condyle, with a medial femoral condylar defect, and after placement of a transcondylar screw through the condylar defect.  Vet. Surg., 44(3):289-296, 2015.

   Nam. J., Perera, P., Gordon, R., Blazek, A.D., Kim, D-G., Tee, B.C., Sun, Z., Eubank, T.D., Zhao, Y., Leblebicioglue, B., Liu, S., Litsky, A.S., Weisleder, N.L., Lee, B.S., Butterfield, T.A., Schneyer, A.L., and Agarwal, S.  Follistatin-Like 3 is a Mediator of Exercise-Driven Bone Formation and Strengthening.  Bone, 78:62-70, 2015.

   Curtis, B., Fajolu, O., Ruff, M., and Litsky, A.  Fixation of Metacarpal Shaft Fractures: Biomechanical Comparison of Intramedullary Nail, Crossed K-wires, and Plate-Screw Constructs.  Ortho. Surg.,         7(3):256-260, 2015.

   Melvin, A., Litsky, A.S., and Juncosa-Melvin, N.  FiberSecure Suture Compared to Braided Polyester Suture.  J. Biomed Mat. Res., Part B, xx(xx):xxx-xxx, 2016.  E-pub ahead of printing: DOI: 10.1002/jbm.b.33657

   Taylor, B.C., Litsky, A.S., Pugh K.J., and Fowler, T.T.  Biomechanical Evaluation of 6.5 mm Cannulated Screws.  J. Surg. Orthop. Adv., 25(1):8-12, 2016.

   Morrison, E.J., Litsky, A.S., Allen, M.J., Fosgate, G.T., and Hettlich, B.F.  Evaluation of Three Human Cervical Fusion Implants for Use in the Canine Cervical Vertebral Column.  Vet. Surg., 45(7):901-908, 2016.

   Mazumder, R., Schroeder, S., Mo, X., Litsky, A.S., Clymer, B.D., White, R.D., and Kolipaka, A.  In-vivo Magnetic Resonance Elastography to Estimate Left Ventricular Stiffness in a Myocardial Infarction Induced Porcine Model.  J. Magnetic Resonance Imaging, 45:1024-1033, 2017.

   Hettlich, B.F., Fosgate, G.T., and Litsky, A.S.  Biomechanical comparison of Two Veterinary Locking Plates to Monocortical Screw/Polymethylmethacrylate Fixation in the Cadaveric Canine Cervical Vertebral Column.  Vet. Surg., 46(1):95-102, 2017. 
 

  • PATENTS

Bending apparatus for material testing and micro-CT imaging, pat. pending

 

  • COURSES

Hard-Tissue Biomaterials
Musculoskeletal Tissue Mechanics
Research Ethics

Honors

  • 20070401-20090401

    Secretary-Treasurer.

  • 20090201

    election to AIMBE.

Journal Articles

2014

  • Hettlich,Bianca,F; Allen,Matthew,J; Glucksman,Gabriela,S; Fosgate,Geoffrey,T; Litsky,Alan,S, 2014, "Effect of an Intervertebral Disk Spacer on Stiffness After Monocortical Screw/Polymethylmethacrylate Fixation in Simulated and Cadaveric Canine Cervical Vertebral Columns." VETERINARY SURGERY 43, no. 8, 988-994 - 988-994.

2013

  • Bishop,Julie,Y; Roesch,Michael; Lewis,Brian; Jones,Grant,L; Litsky,Alan,S, 2013, "A biomechanical comparison of distal clavicle fracture reconstructive techniques.." American journal of orthopedics (Belle Mead, N.J.) 42, no. 3, 114-118 - 114-118.

2012

  • Higuita-Castro,Natalia; Gallego-Perez,Daniel; Pelaez-Vargas,Alejandro; García Quiroz,Felipe; Posada,Olga,M; López,Luis,E; Sarassa,Carlos,A; Agudelo-Florez,Piedad; Monteiro,Fernando,J; Litsky,Alan,S; Hansford,Derek,J, 2012, "Reinforced Portland cement porous scaffolds for load-bearing bone tissue engineering applications.." Journal of biomedical materials research. Part B, Applied biomaterials 100, no. 2, 501-507 - 501-507.
  • Flanigan,David,C; Child,Jeremy,Roberts; Litsky,Alan,S, 2012, "Testing of Double-Stranded Allografts Used in ACL Reconstruction." JOURNAL OF KNEE SURGERY 25, no. 5, 385-390 - 385-390.

2011

  • Thomas, K; Litsky, A; Jones, G; Bishop, JY, 2011, "Biomechanical Comparison of Coracoclavicular Reconstructive Techniques." AMERICAN JOURNAL OF SPORTS MEDICINE 39, no. 4, 804-810 - 804-810.
  • Fowler,T,Ty; Pugh,Kevin,J; Litsky,Alan,S; Taylor,Benjamin,C; French,Bruce,G, 2011, "Medial Malleolar Fractures: A Biomechanical Study of Fixation Techniques." ORTHOPEDICS 34, no. 8, 578-578 - 578-578.
  • Melvin, A; Litsky, A; Mayerson, J; Stringer, K; Melvin, D; Juncosa-Melvin, N, 2011, "An Artificial Tendon to Connect the Quadriceps Muscle to the Tibia." JOURNAL OF ORTHOPAEDIC RESEARCH 29, no. 11, 1775-1782 - 1775-1782.

2010

  • Bellisari,Gregory,E; Kaeding,Christopher,C; Litsky,Alan,S, 2010, "Mechanical evaluation of cross pins used for femoral fixation of hamstring grafts in ACL reconstructions.." Orthopedics 33, no. 10, 722-? - 722-?.
  • Melvin, A; Litsky, A; Mayerson, J; Witte, D; Melvin, D; Juncosa-Melvin, N, 2010, "An Artificial Tendon with Durable Muscle Interface." JOURNAL OF ORTHOPAEDIC RESEARCH 28, no. 2, 218-224 - 218-224.
  • Aros, BC; Pedroza, A; Vasileff, WK; Litsky, AS; Flanigan, DC, 2010, "Mechanical comparison of meniscal repair devices with mattress suture devices in vitro." KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY 18, no. 11, 1594-1598 - 1594-1598.

2008

  • Ishihara A; Shields KM; Litsky AS; Mattoon JS; Weisbrode SE; Bartlett JS; Bertone AL, 2008, "Osteogenic gene regulation and relative acceleration of healing by adenoviral-mediated transfer of human BMP-2 or -6 in equine osteotomy and ostectomy models.." Journal Of Orthopaedic Research: Official Publication Of The Orthopaedic Research Society 26, no. 6, 764 - 764.
  • Bertone A, Goin S, Kamei S, Mattoon J, Litsky A, Weisbrode S, Clarke R, Plauhar P, Kaeding C, 2008, "Metacarpophalangeal collateral ligament reconstruction using small intestinal submucosa in an equine model.." J Biomed Mater Res A 84, no. 1, 219-29 - 219-29.
  • Bertone,Alicia,L; Goin,Scott; Kamei,Sachiko,J; Mattoon,John,S; Litsky,Alan,S; Weisbrode,Steven,E; Clarke,Rhonda,B; Plouhar,Pamela,L; Kaeding,Christopher,C, 2008, "Metacarpophalangeal collateral ligament reconstruction using small intestinal submucosa in an equine model.." Journal of biomedical materials research. Part A 84, no. 1, 219-229 - 219-229.
  • Pozzi, A; Litsky, AS; Field, J; Apelt, D; Meadows, C; Johnson, KA, 2008, "Pressure distributions on the medial tibial plateau after medial meniscal surgery and tibial plateau levelling osteotomy in dogs." VETERINARY AND COMPARATIVE ORTHOPAEDICS AND TRAUMATOLOGY 21, no. 1, 8-14 - 8-14.
  • Glass DH; Roberts CJ; Litsky AS; Weber PA, 2008, "A viscoelastic biomechanical model of the cornea describing the effect of viscosity and elasticity on hysteresis.." Investigative Ophthalmology & Visual Science 49, no. 9, 3919 - 3919.

2007

  • Waselau, Martin; Samii, Valerie, F; Weisbrode, Steven, E; Litsky, Alan, S; Bertone, Alicia L, 2007, "The effect of a magnesium adhesive cement on bone stability and healing following a metatarsal osteotomy in horses.." Am J Vet Res 68, no. 4, 370-378 - 370-378.
  • Henry J, Feinblatt J, Kaeding CC, Latshaw J, Litsky A, Sibel R, Stephens JA, Jones GL, 2007, "Biomechanical analysis of distal biceps tendon repair methods.." The American Journal of Sports Medicine 35, no. 11, 1950-1954 - 1950-1954.
  • Bertone A, Goin S, Kamei S, Mattoon J, Litsky A, Weisbrode S, Clarke R, Plauhar P, Kaeding C, 2007, "Metacarpophalangeal collateral ligament reconstruction using small intestinal submucosa in an equine model.." J Biomed Mater Res A 84, 219-229 - 219-229.
  • Gallagher S, Marras WS, Litsky AS, Burr D, Landoll J, Matkovic V, 2007, "A comparison of fatigue failure responses of old versus middle-aged lumbar motion segments in simulated flexed lifting.." Spine 32, no. 17, 1832-1839 - 1832-1839.
  • Henry, J; Feinblatt, J; Kaeding, CC; Latshaw, J; Litsky, A; Sibel, R; Stephens, JA; Jones, GL, 2007, "Biomechanical analysis of distal biceps tendon repair methods." AMERICAN JOURNAL OF SPORTS MEDICINE 35, no. 11, 1950-1954 - 1950-1954.
  • Waselau, Martin; Samii, Valerie, F; Weisbrode, Steven, E; Litsky, Alan, S; Bertone, Alicia L, 2007, "Effects of a magnesium adhesive cement on bone stability and healing following a metatarsal osteotomy in horses.." American journal of veterinary research 4, 370-8 - 370-8.

2006

  • Bertone, A; Lipson, D; Kamei, J; Litsky, A; Weisbrode, S, 2006, "Effective bone hemostasis and healing using radiofrequency and conductive fluid." CLINICAL ORTHOPAEDICS AND RELATED RESEARCH 446, 278-285 - 278-285.
  • Bertone, Alicia; Lipson, David; Kamei, Janet; Litsky, Alan; Weisbrode, Stephen, 2006, "Effective bone hemostasis and healing using radiofrequency and conductive fluid.." Clinical orthopaedics and related research 446, 278-85 - 278-85.
  • Neat, B; Kowaleski, M, P; Litsky, A, S; Boudrieau, R J, 2006, "The effects of wire diameter and an additional lateral wire on pin and tension-band fixation subjected to cyclic loads.." Veterinary and comparative orthopaedics and traumatology : V.C.O.T 19, no. 4, 213-8 - 213-8.

1998

  • Ebert,Daniel,W; Roberts,Cynthia; Farrar,Stuart,K; Johnston,William,M; Litsky,Alan,S; Bertone,Alicia,L, 1998, "ARTICULAR CARTILAGE OPTICAL PROPERTIES IN THE SPECTRAL RANGE 300-850 NM." JOURNAL OF BIOMEDICAL OPTICS 3, no. 3, 326-333 - 326-333.

Papers in Proceedings

1996

  • Saw, E.; Sandhage, K.H.; Gallagher, P.K.; Litsky, A.S. "Synthesis of hydroxyapatite by the oxidation of solid, metal-bearing precursors." (12 1996).

1991

  • Litsky, A.S.; Torch, M.A.; Anson, L.W.; Klamar, J.E. "Vivo evaluation of self-reinforced polygycolic acid rods for cortical fracture fixation." (1 1991).