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Kimerly Powell

  • Assistant Professor-Clinical, SBS-Biomedical Informatics
  • Assistant Professor, Radiology
  • 1800 Cannon Drive
    310F
    Columbus, OH 43210
  • 614-366-2252

Journal Articles

2013

  • Di Leva G, Piovan C, Gasparini P, Ngankeu A, Taccioli C, Briskin D, Cheung DG, Bolon B, Anderlucci L, Alder H, Nuovo G, Li M, Iorio MV, Galasso M, Ramasamy S, Marcucci G, Perrotti D, Powell KA, Bratasz A, Garofalo M, Nephew KP, Croce CM, 2013, "Estrogen mediated-activation of miR-191/425 cluster modulates tumorigenicity of breast cancer cells depending on estrogen receptor status." PLoS Genet 9, epub -

2012

  • Stredney D, Hittle B, Chen CM, Kerwin T, Bratasz A, Manivannan N, Powell K., 2012, "Virtual simulation of mouse anatomy and procedural techniques.." Student Health Technol Inf 173, 500 - 5.
  • Aeffner F, Bratasz A, Flaño E, Powell KA, Davis IC., 2012, "Postinfection A77-1726 treatment improves cardiopulmonary function in H1N1 influenza-infected mice.." Am J Respir Cell Mol Biol. 47, 543 - 51.
  • Yoo JY, Pradarelli J, Haseley A, Wojton J, Kaka A, Bratasz A, Alvarez-Breckenridge CA, Yu JG, Powell K, Mazar AP, Teknos TN, Chiocca EA, Glorioso JC, Old M, Kaur B., 2012, "Copper chelation enhances antitumor efficacy and systemic delivery of oncolytic HSV.." Clin Cancer research 18, 4931 - 41.
  • Kim Powell and Dave Wilson, 2012, "High Resolution Imaging Techniques for Morphological Phenotyping of Gentically Engineered Mice." Journal Veterinary Pathology

2011

  • Yoo JY, Haseley A, Bratasz A, Chiocca EA Zhang JY, Cain D, Powell K, Kaur B, 2011, "Anti-tumor efficacy of 34.5ENVE: a transcriptionally retargeted and “Vstat120â€� oncolytica virus." Molecular Therapy

2010

  • Swanson MS, Prescott JW, Best TM, Powell K, Jackson RD, Haq F, Gurcan MN, 2010, "Semi-automated segmentation to assess the lateral meniscus in normal and osteoarthritic knees." Osteoarthritis Cartilage 3, no. 18, 344 - 353.
  • Jones GN, Pringle DR, Yin Z, Carlton MM, Powell KA, Weinstein MB, Toribio RE, La Perle KM, Kirschner LS, 2010, "Neural crest-specific loss of Prkar1a causes perinatal lethality resulting from defects in intramembranous ossification." Mol Endocrinol 8, no. 24, 1559 - 1568.
  • Vignon E, Brandt KD, Mercier C, Hochberg M, Hunter D, Mazzuca S, Powell K, Wyman B, Le Graverand MP, 2010, "Alignment of the medial tibial plateau affects the rate of joint space narrowing in the osteoarthritic knee." Osteoarthritis Cartilage 11, no. 18, 1436 - 1440.
  • Enomoto H, Nelson CM, Somerville RP, Mielke K, Dixon LJ, Powell K, Apte SS, 2010, "Cooperation of two ADAMTS metalloproteases in closure of the mouse palate identifies a requirement for versican proteolysis in regulating palatal mesenchyme proliferation." Development 23, no. 137, 4029 - 4038.

2008

  • Villarruel SM, Boehm CA, Butler RS, Pennington M, Powell KA, Muschler GF, 2008, "The effect of oxygen tension on the in vitro assay of human osteoblastic connective tissue progenitor cells." JOR
  • Codsi M, Bennetts C, Gordiev K, Boeck D, Kwon Y, Brems JJ, Davros W, Powell K, Iannotti JP, 2008, "Normal Glenoid Vault Anatomy and Validation of a Novel Glenoid Implant Shape." JSES 17, no. 3, 479 - 486.

2007

  • Pavel E, Zhao W, Powell KA, Weinstein M, Kirschner LS, 2007, "Analysis of new allele of limb deformity (ld) reveals tissue- and age-specific transcriptional effects of the Ld global control region." Int J Dev Biol 51, no. 4, 273 - 281.
  • Powell KA, Nakamoto C, Villarreul S, Boehm C, Muschler G, 2007, "Quantitative image analysis of connective tissue progenitors." Anal Quant Cytol Histol 29, 112 - 121.

2006

  • Showalter C, Clymer BD, Richmond B, Powell K, 2006, "Three-Dimensional texture analysis of cancellous bone cores evaluated at clinical CT resolutions." Osteoporosis Intl 17, no. 2, 259 - 266.

2005

  • Kobayashi N, Togowa D, Fujishiro T, Powell KA, Turner AS, Seim HB, 3rd, Bauer T, 2005, "Histological and radiographic evaluation of polymethacyrlate with two different concentrations of barium sulfate in sheep vertebroplasty model." J Biomed Mater Res A 75, no. 1, 123 - 127.
  • YWKwon, KA Powell, JK Yum, JJ Brems, JP Iannotti., 2005, "Use of 3-D computed tomography for the analysis of glenoid morphometry." JSES 14, no. 1, 85 - 90.
  • Midura Rj, Ibiwoye MO, Powell KA, Sakai Y, Doehring T, Grabiner MD, Patterson TE, Zborowski, Wolfman A, 2005, "Pulsed electromagnetic field treatments enhance the healing of fibular osteotomies." J Orthop Res 23, no. 5, 1035 - 1046.
  • Muschler GF, Matsukura Y, Nitto H, Boehm C, Valdevit AD, Kambric HE, Davros WJ, Easley KA, Powell KA, 2005, "Selective retention of bone marrow-derived cells to enhance spinal fusion." Clin Orthop Relat Red 432, 242 - 251.
  • Safran O, Derwin KA, Powell K, Iannotti JP, 2005, "Changes in rotator cuff muscle volume, fat content, and passive mechanics after chronic detachment in canine model." J Bone Joint Surgery Am 12, 2662 - 2670.
  • Powell KA, Latson L, Ibiwoye MO, Wolfman A, Grabiner MD, Zborowski M, Sakia Y, Midura RJ, 2005, "In vivo longitudinal assessment of bone resorption in a fibular osteotomy model using micro-computed tomography." Iowa Orthop J 25, 132 - 138.

2004

  • MO Ibiwoye, KA Powell, MD Grabiner, TE Patterson, Y Sakai, M Zborowski, A Wolfman, RJ Midura, 2004, "Bone mass is preserved in a critical-sized osteotomy by low-energy pulsed electromagnetic fields as quantitated by in vivo micro-computed tomgraphy." J Orthopaedic Research 22, no. 5, 1086 - 1093.
  • JP Gorski, Wang A, D Lovitch, D Law, K Powell, RJ Midura, 2004, "Extracellular bone acidic glycoprotein-75 defines condensed mesenchym regions to be mineralized and localizes with bone sialoprotein during intramembranous bone formation 1,2." J Biol Chem 279, no. 24, 25455 - 25463.
  • RJ Midura, A Wang, D Lovitch, D Law, K Powell, JP Gorski, 2004, "Bone acidic glycoprotein-75 delineates the extracellular sites of future bone sialoprotein accumulation and apatite nucleation in osteoblastic cultures.." J Biol Chem 279, no. 24, 25464 - 25473.

2003

  • Muschler GF, Nitto H, Matsukara Y, Boehm C, Valdevit A, Kambic H, Davros W, Powell K, Easly K, 2003, "Spine fusion using cell matrix composites enriched in bone marrow- derived cells." Clin Orthop Relat Res no. 407, 102 - 118.
  • Latson L, Sebek B, Powell KA, 2003, "Automated cell nuclear segmentation in color images of hematoxylin and eosin-stained breast biopsy." Anal Quant Cytol Histol 25, no. 6, 321 - 331.
  • Sturm B, Powell K, Stillman AE, White RD, 2003, "Registration of 3D CT Angiography MR Images in Coronary Artery Disease Patients." International J. Cardiovascular Imaging 19, no. 4, 281 - 293.

2002

  • R. Sivaramakrishna, K.A. Powell, M.L. Lieber, W.A. Chilcote, R. Shekhar, 2002, "Texture analysis of lesions in breast ultrasound images." Computerized Medical Imaging and Graphics 26, 303 - 307.
  • Ymani MH, Tuzcu EM, Starling RC, Ratliff NB, Yu Y, Vince G, Powell K, Masri CS, McCarthy PM, Young JB, 2002, "Myocardial ischemic injury after heart transplantation is associated with upregulation of vitronectin receptor (alpha(v)beta3), activation of the matrix metalloproteinase induction system, and subsequent development of coronary vasculopathy." Circulation 105, 1955 - 1961.
  • Yamani MH, Tuzcu EM, Starling RC, Ratliff NB, Yu Y, Vince G, Powell K, Masri CS, McCarthy PM, Young JB, 2002, "Peritransplant myocardial ischemia injury is associated with upregulation of vitronectin receptor, matrix metalloprotienase induction and subsequent development of coronary vasculopathy." J Heart Lung Transplant 21, 73 - 74.

2001

  • Latson L, Powell KA, Sturm B, Schvartzman PR, White RD, 2001, "Clinical validation of an automated boundary tracking algorithm on Cardiac MR images." International J of Cardiac Imaging 17, 279 - 286.
  • Sivaramakrishna R, Obuchowski NA, Chilcote WA, Powell KA, 2001, "Automatic segmentation of mammographic density." Academic Radiology 8, no. 12, 250 - 256.
  • Young AA, Dokos S, Powell KA, Sturm B, McCulloch AD, Starling RC, McCarthy PM, White RD, 2001, "Regional heterogeneity of function in nonischemic dilated cardiomyopathy." Cardiovascular Research 49, no. 2, 308 - 318.
  • Obuchowski NA, Graham RJ, Baker ME, Powell KA, 2001, "Ten Criteria for effective screening: Their application to multi-slice CT screening for pulmonary and colorectal cancers." AJR 176, 1357 - 1362.

2000

  • Obuchowski NA, Lieber M, Powell KA, 2000, "Data analysis for detection and localization of multiple radiographic signals with application to mammography." Academic Radiology 7, 516 - 525.
  • Sivaramakrishna R, Obuchowski NA, Chilcote WA, Cardenosa G, Powell KA, 2000, "Comparing the performance of mammographic enhancement algorithms - A preference study." AJR 175, 45 - 51.
  • Powell KA, Mallasch P, Obuchowski N, Kerczewski R, Ganobcik S, Cardenosa G, Chilcote W, 2000, "Clinical evaluation of wavelet-compressed digitized film mammograms." Academic Radiology 7, 311 - 316.

1999

  • Powell KA, Obuchowski NA, Yeung AC, Kennedy JA, Cornhill JF, 1999, "Correlation of Valve Closing to Visualization of Single-Leg Separation in Radiographic Images of Bjork-Shiley Convexo-Concave Heart Valves." J Heart Valve Disease 8, 399 - 403.
  • Powell KA, Obuchowski NA, Chilcote WA, Barry MM, Ganobcik SN, Cardenosa G, 1999, "Film-Screen Mammograms versus Digitized Mammograms: Assessment of Clinical Equivalence." AJR 173, 889 - 894.
  • Powell KA, Obuchowski NA, Davros W, Chilcote WA, 1999, "Quantitative analysis of breast parenchymal density: correlation with women's age." Academic Radiology 6, 742 - 747.

1996

  • Powell KA, Obuchowski NA, Mueller KD, LaPresto E, Hwang CG, Hirsch JL, Nissen SE, Cornhill JF, 1996, "Quantitative Detection of Outlet Strut Separations in Bjork-Shiley Convexo-Concave Mitral Valves." Circulation 94, 3251 - 3256.
  • Nakatani S, White RD, Powell KA, Lever HM, Thomas JD, 1996, "Impact of Ventricular wall curvature on regional function in hypertrophic cardiomyopathy: assessment with dynamic magnetic resonance imaging." Am J Cardio 77, 618 - 622.
  • Mueller K, LaPresto EL, Powell KA, Hirsch JL, Cornhill JF, 1996, "A Medical Workstation for the Display and Analysis of Multi-Frame Digital Cineradiographic Data." Computers in Medicine and Biology 26, 385 - 400.
  • Pohlman S, Powell KA, Obuchowski NA, Chilcote WA, Grundfest-Broniatowski S, 1996, "Quantitative Classification of Breast Tumors in Digitized Mammograms." Medical Physics 23, 1337 - 1346.

1995

  • Pu M, Vandervoort PM, Greenberg NL, Powell KA, Griffin BP, Thomas JD, 1995, "Impact of wall constraint on the velocity distribution in the proximal flow convergence zone: Implications for color Doppler quantification of mitral regurgitation." JACC 27, 706 - 713.
  • Cosgrove DM, Arcidi J, Rodriguez L, Stewart W, Powell K, Thomas JD, 1995, "Initial Experience with the Cosgrove-Edwards Annuloplasty System." Ann Thorac Surg 60, 499 - 504.
  • Vandervoort PM, Greenberg NL, Pu M, Powell KA, Cosgrove DM, Thomas JD, 1995, "Pressure recovery in bileaflet heart valve prostheses." Circulation 92, 3464 - 3472.

1989

  • Alben JO, Fiamingo FG, Croteau AA, Hemann CF, Powell KA, Molleran VM, Park S, 1989, "X-ray absorption spectroscopy of myoglobin and iron porphyrin derivatives." Physica B 158, 87 - 89.

1988

  • Alben JO, Fiamingo FG, Croteau AA, Hemann CF, Powell KA, Molleran VM, Park S, 1988, "Instrumental barriers in biological Fourier transform infrared spectroscopy." Microchimica Acta 1, 335 - 338.

Presentations

  • "Proximal Convergence Analysis of Elliptical Orifices in Three-Dimensions." 1995, Presented at BMES,
  • "Classification of breast lesions based on quantitative measures of tumor morphology." 1995, Presented at IEEE in Medicine and Biology,
  • "Clinical Validation of Automated Boundary Tracing using Cardiac MR Images." 1998, Presented at Computers in Cardiology,
  • "MRI-based 3D regional circumferential wall stress changes from partial left ventriculectomy." 2000, Presented at 3rd Annual meeting of the Society of Cardiovascular Magnetic Resonance Imaging,
  • "Computation of transmitral pressure gradients from color Doppler M-mode images." 1993, Presented at American Society Mechanical Engineering,
  • "Accuracy of valve area measurements: Gorlin or Doppler?." 1993, Presented at American Society of Echocardiography,
  • "The effective area of a stenotic orifice depends critically on inlet geometry: digital Doppler analysis of a pulsatile in vitro model." 1993, Presented at American College of Cardiology,
  • "3-D Reconstruction of Mitral Annulus from 2-D Transesophageal Echocardiographic Images." 1994, Presented at Computers in Cardiology,
  • "Quantitative detection and classification of single-leg separations in the outlet struts of Bjork-Shiley convexo-concave heart valves." 1994, Presented at World Congress on Medical Physics and Biomedical Engineering,
  • "A fast and accurate implementation of the algebraic reconstruction technique." 1994, Presented at World Congress on Medical Physics and Biomedical Engineering,
  • "Functional Heterogeneity And Recovery of Septal Function After Successful LV Volume Reduction in DCM." 1999, Presented at AHA,
  • "Image Fusion of 4D Cardiac CTA and MR Images." 2001, Presented at 30th Applied Imagery Pattern Recognition workshop,
  • "Co-registration of 3D CTA and MR Images for Therapeutic Planning in Coronary Artery Disease." 2001, Presented at BMES,
  • "Comparative analysis of iron chloride and m-oxo porphyrin derivatives using a refined EXAFS analysis procedure." 1992, Presented at ASBMB/Biophysical Society National Conference,
  • "Finite Element Modeling of Atherosclerotic Plaque." 1993, Presented at Computers in Cardiology,
  • "VIRTUAL SIMULATION OF MOUSE ANATOMY AND PROCEDURAL TECHNIQUES." 2012, Presented at MMVR 19 NextMed, Newport Beach,
  • "Infrared studies of des-His and iodoacetamide derivatives of carboxyhemoglobin." 1987, Presented at Biophysical Society National Conference,
  • "Demonstration of Improved Ventricular Function in Dilated Cardiomyopathy by Surgical Left-Ventricular Remodeling using Dynamic Cardiac MRI." 1997, Presented at AHA,
  • "Three Dimensional Shape, Deformation, and Motion Analysis of Mitral Annuli using Transesophageal echorcardiagraphic data." 1998, Presented at SPIE Medical Imaging,
  • "Clinical Validation of an Automated Boundary Tracking Algorithm on Cardiac Magnetic Resonance Images." 2000, Presented at 3rd Annual meeting of the Society of Cardiovascular Magnetic Resonance Imaging,
  • "Virtual Simulation of Mouse Anatomy and Procedural Techniques." 2011, Presented at World Molecular Imaging Conference, San Diego,
  • "The Use of Magnetic Resonance Spectroscopy (MRS) in Monitoring Vestibular Schwannoma Growth and Treatment-effect." 2011, Presented at Annual NF Conference Children's Tumor Foundation 2011,
  • "Remote Interactive Volume Visualization Infrastructure for Researchers." 2011, Presented at AMIA, Washington DC,
  • "Automated Segmentation and Separation of Cell Nuclei in Breast Pathology Images." 2001, Presented at BMES,
  • "Characterization of rat and opossum microsomal cytochromes P-450 and P-420 by low temperature visible and FT-IR spectra." 1986, Presented at Society for Applied Spectroscopy Conference,
  • "An Automated Temporal Alignment Technique for the Translational and Rotational Correction of Digital Radiographic Images of Bjork-Shiley Heart Valves." 1993, Presented at Computers in Cardiology,
  • "Left ventricular function one year after partial left ventriculectomy using dynamic cardiac MRI." 1998, Presented at AHA,
  • "Functional heterogeneity and recovery of septal function after successful LV volume reduction in DCM." 1999, Presented at 72nd Scientific Sessions of the American Heart Association,
  • "Comparing the performance of image enhancement algorithms utilizing different methodologies in visualizing known lesions in digitized mammograms in a soft-copy display setting." 2000,
  • "The Effect of Oxygen Tension on Colony formation of Human Connective Tissue Progenitor Cells." 2004, Presented at 50th Annual Meeting of the Orthopaedic Research Society,
  • "FT-IR studies of des-His and iodoacetamide derivatives of carboxyhemoglobin." 1986, Presented at Society for Applied Spectroscopy Conference,
  • "Noninvasive reconstruction of instantaneous left ventricular filling pressures using color Doppler M-mode inflow velocities." 1993, Presented at American Society of Echocardiography,
  • "Noninvasive assessment of diastolic function using digital analysis of color Doppler M-mode velocities: and in-vivo study." 1993, Presented at American Society of Echocardiography,
  • "Use of proximal convergence method to quantitate mitral regurgitation in patients with flail leaflet: lessons from fluid dynamic modeling." 1993, Presented at American College of Cardiology,
  • "3-D Micro-CT Imaging: A New Dimension in Mouse Skeletal Development." 2004, Presented at 50th Annual Meeting of the Orthopaedic Research Society,
  • "In Vivo Longitudinal Assessment of Bone Loss in Fibula Osteotomy Model Using Micro-computed Tomorgraphy." 2004, Presented at 50th Annual Meeting of the Orthopaedic Research Society,
  • "Bone Formation Following OP-1 Implantation is Improved by Addition of Autogenous Bone Marrow Cells." 2004, Presented at 50th Annual Meeting of the Orthopaedic Research Society,
  • "A new transcriptionally driven oncovirus with Vstat120 expression has antiangiogenic and anti-tumorigenic effects." 2011, Presented at ISMRM 2011,
  • "Statistical fractal a border features for mammographic breast mass analysis." 1999, Presented at SPIE Medical Imaging,
  • "Comparing the performance of image enhancement algorithms utilizing different methodolgies in visualizing known lesions in digitized mammograms in soft-copy display environment." 1999, Presented at SPIE Medical Imaging,
  • "Donor Intracranial B leeding is Associated with Metalloproteinase System and Subsequent Development of Allograft vasculopathy." 2003, Presented at AHA,
  • "Automated segmentation of epithelial cell nuclei in color images of breast biopsy." 2001, Presented at Harry and Elsa Jiler American Cancer Society Professors Meeting,
  • "Telemammography using Satellite Communications." 1997, Presented at RSNA,
  • "Digital radiographic analysis of single-leg separations (SLS) in the outlet struts of Bjork-Shiley convexo-concave valves." 1993, Presented at Computer Assisted Radiology,
  • "Rotator Cuff Muscle Atrophy and Passive tissue Tension After Chronic Detachment in a Canine Model." 2004, Presented at 50th Annual Meeting of Orthopaedic Research Society,
  • "Comparing the performance of image enhancement algorithms utilizing different methodolgies in visualizing known lesions in digitized mammograms in soft-copy display environment." 1999, Presented at RSNA,
  • "Texture descriptors for mammographic mass characterization." 1999, Presented at Engineering Medicine and Biology Society,
  • "Diagnostic Accuracy of digitized mammograms versus film-screen mammograms." 1998, Presented at 4th International Workshop on Digital Mammography,
  • "Automated Classification of Breast Biopsy Sections, Annals of Biomedical Engineering." 1998, Presented at BMES,
  • "System considerations for satellite transmission of digitized mammograms." 1998, Presented at 4th International Workshop on Digital Mammography,

Papers in Proceedings

2011

  • Niranchana Manivannan, Bradley D. Clymer, Anna Bratasz, Kimerly A. Powell "Orthogonal Super Resolution Reconstruction for 3D Isotropic Imaging in 9.4 MRI." in ISMR Proceedings 2011. (1 2011).
  • Yoo JY, Haseley A, Bratasz A, Chiocca EA Zhang JY, Cain D, Powell K, Kaur B. "A new transcriptionally driven oncovirus with Vstat120 expression has antiangiogenic and anti-tumorigenic effects." in Proceedings ISMRM 2011. (1 2011).

2003

  • L. Latson, B. Kuban, J. Bryan, D. Stredney, W. Davros, R. Midura, S. Apte, K.Powell "X-ray Micro-Computed Tomography System: Novel Applications in Bone Imaging." in 25th International Conference of the IEEE Engineering Medicine and Biology Society. (1 2003). 2:1058 - 1061.

Patents

  • KA Powell. "Glenoid Component for Shoulder Arthroplasty." Patent number: DEP5596USNP
  • KA Powell. "Image Analysis of Biological Objects." Patent number: CCF-7470PV