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Katelyn Swindle-Reilly

  • Assistant Professor, Chemical & Biomolecular Eng
  • Assistant Professor, Ophthalmology
  • Assistant Professor, Biomedical Engineering
  • 299 Bevis Hall
    1080 Carmack Road
    Columbus, OH 43210
  • 614-292-4602

About

Education

  • B.S., Georgia Institute of Technology, 2004
  • M.S., Washington University in St. Louis, 2006
  • Ph.D., Washington University in St. Louis, 2008

 

Key Honors and Distinctions

  • REACH for Commercialization (2017)
  • Washington University in St. Louis Cherryll Walzel-Frick and F. Alan Frick Graduate Scholar (2004-2005)
  • Georgia Institute of Technology President’s Undergraduate Research Award (2004)
  • Georgia Institute of Technology Omega Chi Epsilon Excellence Award (2004)
  • Georgia Institute of Technology President’s Scholarship (2000-2004)

 

RESEARCH AREAS – Swindle-Reilly Lab for Biomimetic Polymeric Biomaterials

  • Biomaterials; Polymers; Ocular; Wound Healing; Drug Delivery
  • Graduate student research opportunities are currently available.

 

  • PUBLICATIONS

http://scholar.google.com/citations?user=11uXSw4AAAAJ&hl=en

Swindle-Reilly KE, Reilly MA, Ravi N. Current concepts in the design of hydrogels as vitreous substitutes. In Biomaterials and regenerative medicine in ophthalmology, 2nd edition. Chirila TV, Harkin D, eds. Ch 5. Woodhead Publishing Limited, 2016.

Salamone JC, Salamone AB, Swindle-Reilly K, Leung KX-C, McMahon, RE. Grand challenge in Biomaterials-wound healing. Regenerative Biomaterials. 3(2): 127-128, 2016.

Swindle-Reilly KE, Paranjape CS, Miller CA. Electrospun poly(caprolactone)-elastin scaffolds for peripheral nerve regeneration. Prog. Biomater. 3:20, 2014.

Swindle-Reilly KE, Papke JB, Kutosky HP, Throm A, Hammer JA, Harkins AB, Willits RK. The impact of laminin on 3D neurite extension in collagen gels. J. Neural Eng. 9:046007, 2012.

Reilly MA, Swindle-Reilly KE, Ravi N. Hydrogels for intraocular lenses and other ophthalmic prostheses. In Biomedical hydrogels: Biochemistry, manufacture and medical applications. Rimmer S, ed. Ch 7. Woodhead Publishing Limited, 2011.

Swindle-Reilly KE, Ravi N. Designing hydrogels as vitreous substitutes in ophthalmic surgery. In Biomaterials and regenerative medicine in ophthalmology. Chirila TV, ed. Ch 13. Woodhead Publishing Limited, 2010. 

Swindle-Reilly KE, Shah M, Hamilton PD, Erskin T, Kaushal S, Ravi N. Rabbit study of an in situ forming hydrogel vitreous substitute. Invest. Ophthalmol. Vis. Sci. 50: 4840-4846, 2009.

Swindle KE, Hamilton PD, Ravi N. In situ formation of hydrogels as vitreous substitutes: viscoelastic comparison to porcine vitreous. J. Biomed. Mater. Res. 87A(3): 656-665, 2008.

Swindle KE, Ravi N. Recent Advances in Polymeric Vitreous Substitutes. Exp. Rev. Ophthalmol. 2(2): 255-265, 2007.

Ravi N, Wan KT, Swindle K, Hamilton PD, Duan G. Development of techniques to compare mechanical properties of reversible hydrogels with spherical, square columnar and ocular lens geometry. Polymer. 47: 4203-4209, 2006.

 

  • PATENTS

Salamone JC, Chen-Leung X, Salamone AB, Reilly KE. Compositions for Enzymatic Debridement. US 9,592,280, Mar. 14, 2017.

Salamone JC, Salamone AB, Reilly KE, Suggs LJ, Chung E, Leung KX-C. Composition and Kits for Pseudoplastic Microgel Matrices. US Patent Application 14/689,625, Mar. 17, 2015.

Salamone JC, Salamone AB, Chen-Leung X, Reilly KE. Compositions for Treating Pruritis. US Patent Application 14/511,988, Oct. 10, 2014.

Salamone JC, Reilly KE, Nixon RT, Salamone AB, Chen-Leung X. Composition and Kits for Inhibition of Pathogenic Microbial Infection and Methods of Using the Same. US Patent Application 14/504,079, Oct. 1, 2014.

Salamone JC, Reilly KE, Salamone AB, Chen X. Non-Self-Adherent Coating Materials. US 8,877,882, Nov. 4, 2014.

Salamone JC, Chen KX, Salamone AB, Reilly KE. Delivery of Biologically-Active Agents from Volatile, Hydrophobic Solvents. US 8,852,648, Oct. 7, 2014.

 

 

Dr. Swindle-Reilly’s research focuses on the design of polymeric biomaterials for soft tissue repair and drug delivery with focused applications in ophthalmology and wound healing. Studies in the lab focus on polymer synthesis, mechanical characterization, cell-material interactions, and controlled release. A major focus of our work is engineering biomimetic polymers that have properties similar to the native tissue to improve wound healing and outcomes after ophthalmic surgery. Our laboratory is currently investigating materials-based solutions for corneal wound healing, cataract surgery, vitreoretinal surgery, and optic neuropathy.

 

Honors

  • March, 2006

    Washington University Graduate Student Symposium Award.

  • August, 2004-
    August, 2005

    The Cherryll Walzel-Frick and F. Alan Frick Graduate Scholar.

  • August, 2000-
    August, 2004

    President’s Scholarship.

  • December, 2000-
    August, 2004

    Faculty Honors, Dean's List.

  • May, 2004

    Omega Chi Epsilon Excellence Award.

  • March, 2004

    Georgia Tech President’s Undergraduate Research Award.

  • August, 2000-
    May, 2001

    AFCEA Scholarship.

  • January, 2001

    Women in Engineering Scholarship.

  • January, 2001

    Society of Women Engineers Outstanding Sophomore Engineer.

Chapters

2016

  • Swindle-Reilly, K.E.; Reilly, M.A.; Ravi, N.. 2016. "Current concepts in the design of hydrogels as vitreous substitutes." In Biomaterials and Regenerative Medicine in Ophthalmology: Second Edition,

2011

  • Reilly, M.A.; Swindle-Reilly, K.E.; Ravi, N.. 2011. "Hydrogels for intraocular lenses and other ophthalmic prostheses." In Biomedical Hydrogels: Biochemistry, Manufacture and Medical Applications,

2009

  • Swindle-Reilly, K.E.; Ravi, N.. 2009. "Designing hydrogels as vitreous substitutes in ophthalmic surgery." In Biomaterials and Regenerative Medicine in Ophthalmology,

Journal Articles

2018

  • Tram, N.K.; Swindle-Reilly, K.E., 2018, "Rheological properties and age-related changes of the human vitreous humor." Frontiers in Bioengineering and Biotechnology 6, no. DEC,
  • Wang, Q.; Huang, H.; Niu, Y.; Zhang, X. et al., 2018, "Microscale cell stretcher to generate spatially uniform equi-biaxial strain using an elastomeric membrane with a contoured thickness profile." Sensors and Actuators, B: Chemical 273, 1600-1609 - 1600-1609.

2016

  • Salamone, J.C.; Salamone, A.B.; Reilly, K.E.; Leung, K.X.C. et al., 2016, "Grand challenge in Biomaterials-wound healing.." Regenerative Biomateirals 3, no. 2, 127-128 - 127-128.

2014

  • Reilly, K.E.; Paranjape, C.S.; Miller, C.A., 2014, "Electrospun poly(caprolactone)-elastin scaffolds for peripheral nerve regeneration." Progress in Biomaterials 3, 20-20 - 20-20.

2012

  • Swindle-Reilly, K.E.; Papke, J.B.; Kutosky, H.P.; Throm, A. et al., 2012, "The impact of laminin on 3D neurite extension in collagen gels.." J Neural Eng 9, no. 4, 046007 - 046007.

2009

  • Swindle-Reilly, K.E.; Shah, M.; Hamilton, P.D.; Eskin, T.A. et al., 2009, "Rabbit study of an in situ forming hydrogel vitreous substitute.." Invest Ophthalmol Vis Sci 50, no. 10, 4840-4846 - 4840-4846.

2008

  • Swindle, K.E.; Hamilton, P.D.; Ravi, N., 2008, "In situ formation of hydrogels as vitreous substitutes: Viscoelastic comparison to porcine vitreous." Journal of Biomedical Materials Research - Part A 87, no. 3, 656-665 - 656-665.

2007

  • Swindle, K.E.; Ravi, N., 2007, "Recent advances in polymeric vitreous substitutes." Expert Review of Ophthalmology 2, no. 2, 255-265 - 255-265.

2006

  • Ravi, N.; Wan, K.T.; Swindle, K.; Hamilton, P.D. et al., 2006, "Development of techniques to compare mechanical properties of reversible hydrogels with spherical, square columnar and ocular lens geometry." Polymer 47, no. 11, 4203-4209 - 4203-4209.

Presentations

  • "A New Skin Protectant Offers Reduced Tack and Self-Adherence While Providing a Safe, Non-Stinging, and Effective Barrier Film." 2017, Presented at The Symposium on Advanced Wound Care,
  • "Comparison of viscoelastic properties of porcine vitreous to copolymeric hydrogels evaluated as potential vitreous substitutes." 2016, Presented at ARVO Annual Meeting,
  • "Novel developments in amphiphilic polymers for wound care." 2016, Presented at Translational to Clinical (T2C) Regenerative Medicine Wound Care Conference,
  • "Effect of additives on neurite growth in collagen gels." 2010, Presented at BMES Annual Meeting,
  • "Electrospun scaffolds for peripheral nerve regeneration." 2009, Presented at AIChE Annual Meeting,
  • "Optimizing electrospun poly(E-caprolactone) nanofibrous scaffolds for airway tissue engineering." 2009, Presented at BMES Annual Meeting,
  • "Effect of additives on neurite length and mechanical properties of collagen gels." 2009, Presented at BMES Annual Meeting,
  • "Optimized design of thiolated hydrogel vitreous substitutes that form in situ." 2009, Presented at ACS National Meeting,
  • "A thiolated hydrogel vitreous substitute that forms in situ." 2008, Presented at BMES Annual Meeting,
  • "Development of in situ forming vitreous substitutes from derivatives of poly(methacrylamide).." 2008, Presented at ARVO Annual Meeting,
  • "Development of a biomimetic hydrogel vitreous substitute that forms in situ." 2008, Presented at ARVO Annual Meeting,
  • "A novel vitreous substitute: an in situ polymerizing hydrogel and in-vivo testing in the rabbit model." 2007, Presented at American Society of Retina Specialists Meeting,
  • "Optimized design of in situ forming vitreous substitutes." 2007, Presented at The Society of Rheology 79th Annual Meeting,
  • "Evaluation of an in situ forming hydrogel as a vitreous substitute." 2007, Presented at ARVO Annual Meeting,
  • "In situ formation of copolymeric hydrogels as vitreous substitutes." 2007, Presented at Society for Biomaterials Annual Meeting,
  • "Characterization of copolymeric hydrogel vitreous substitutes that gel in situ." 2007, Presented at ACS National Meeting,
  • "Preventing Blindness – Replacing the Vitreous with Hydrogels." 2006, Presented at Washington University Graduate Student Symposium,
  • "In situ forming hydrogels as vitreous substitutes." 2007, Presented at Washington University Graduate Student Symposium,
  • "Advancements in the development of artificial vitreous humor utilizing polyacrylamide copolymers with disulfide crosslinkers." Presented at ACS National Meeting,
  • "Comparison of crosslink density measurements in hydrogels employing disulfide crosslinker." 2005, Presented at ACS Midwest Regional Meeting,
  • "Study of Inhibitors of HTLV-I Protease." Presented at ACS National Meeting,
  • "Design of in situ gelling biomimetic vitreous substitutes." 2008, Presented at Institute for Medicine and Engineering,
  • "Design of in situ gelling biomimetic vitreous substitutes." 2008, Presented at Biomedical Engineering,
  • "Design of biomimetic polymeric biomaterials." 2010, Presented at Chemical & Biomedical Engineering,
  • "Polymeric biomaterials for soft tissue repair and drug delivery." 2015, Presented at Biomedical Engineering,
  • "Design of polymeric biomaterials." 2013, Presented at Biomedical Engineering,
  • "Design of polymeric biomaterials." 2013, Presented at Engineering Science,
  • "Design of polymeric biomaterials." 2012, Presented at Materials Science, Engineering, and Commercialization,
  • "Design of biomimetic polymeric biomaterials." 2011, Presented at Chemical and Biological Engineering,
  • "Design of biomimetic polymeric biomaterials." 2010, Presented at Chemical Engineering,
  • "Polymeric biomaterials for soft tissue repair and drug delivery." 2015, Presented at Biomedical Engineering, Chemical and Biomolecular Engineering, Materials Science and Engineering,
  • "Design of polymeric biomaterials for ocular applications." 2016, Presented at College of Optometry,
  • "Design of polymeric biomaterials for ophthalmic applications." 2016, Presented at Ophthalmic Engineering Grand Rounds,
  • "Design of biomimetic polymeric biomaterials for ophthalmic applications." 2017, Presented at DHLRI Research In Progress,
  • "Development of biomaterials and models for ophthalmic applications." 2017, Presented at Ophthalmology Research Meeting,
  • "Polymers in wound care and ophthalmic applications." 2017, Presented at Engineering in Healthcare: Industry and Research Symposium,
  • "Polymeric biomaterials for ocular tissue repair and drug delivery." 2017, Presented at Big Ten Speaker Exchange, Biomedical Engineering,
  • "Polymeric biomaterials for ocular tissue repair and drug delivery." 2017, Presented at Ophthalmic Engineering Journal Club,
  • "Sustained Drug Delivery Device for Treating Wet Age-related Macular Degeneration." 2018, Presented at Engineering in Healthcare: Industry and Research Symposium,
  • "Rheology of the Human Vitreous Humor." 2018, Presented at Engineering in Healthcare: Industry and Research Symposium,
  • "Sustained Release Anti-VEGF by Microparticles for Treating Wet Age-Related Macular Degeneration." 2018, Presented at Society for Biomaterials Annual Meeting,
  • "Influence of Substrate Chemical and Mechanical Properties on Lens Epithelial Cell Behavior." Presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO),

Papers in Proceedings

2019

  • Soltisz, A.M.; Thobe, S.M.; Ruzga, M.N.; Reilly, M.A. et al. "Evaluation of semi-interpenetrating network for treating traumatic optic neuropathy." (1 2019).
  • Jiang, P.; Lannutti, J.J.; Ohr, M.P.; Swindle-Reilly, K.E. "Injectable biodegradable bi-layered capsule for sustainable delivery of protein therapeutics." (1 2019).
  • Tram, N.K.; Jacobs, K.M.; Swindle-Reilly, K.E. "An antioxidant-releasing hydrogel vitreous substitute." (1 2019).

2009

  • Swindle-Reilly,Katelyn,E; Hamilton,Paul,D; Ravi,Nathan "Optimized design of thiolated hydrogel vitreous substitutes that form in situ." in American Chemical Society. (8 2009).
  • Swindle-Reilly KE, Miller CA "Electrospun scaffolds for peripheral nerve regeneration." in AIChE National Meeting. (1 2009).
  • Reilly, K.E.; Hamilton, P.D.; Ravi, N. "Optimized design of thiolated hydrogel vitreous substitutes that form in situ." in American Chemical Society. (8 2009).
  • Reilly, K.E.; Miller, C.A. "Electrospun scaffolds for peripheral nerve regeneration." in AIChE Annual Meeting. (11 2009).
  • Swindle-Reilly, K.E.; Miller, C.A. "Electrospun scaffolds for peripheral nerve regeneration." (12 2009).
  • Swindle-Reilly, K.E.; Hamilton, P.D.; Ravi, N. "Optimized design of thiolated hydrogel vitreous substitutes that form in situ." (8 2009).
  • Swindle-Reilly, K.E.; Hamilton, P.D.; Ravi, N. "Optimized design of thiolated hydrogel vitreous substitutes that form in situ." (8 2009).

2007

  • Swindle KE, Hamilton PD, Shui YB, Beebe DC, Ravi N. "Characterization of copolymeric hydrogel vitreous substitutes that gel in situ." (1 2007).
  • Reilly, K.E.; Hamilton, P.D.; Shui, Y.B.; Beebe, D.C. et al. "Characterization of copolymeric hydrogel vitreous substitutes that gel in situ." in American Chemical Society. (3 2007).

2006

  • Swindle,Katelyn,E; Hamilton,Paul,D; Ravi,Nathan "Advancements in the development of artificial vitreous humor utilizing polyacrylamide copolymers with disulfide crosslinkers." in 231st National Meeting of the American-Chemical-Society. (3 2006).
  • Reilly, K.E.; Hamilton, P.D.; Ravi, N. "Advancements in the development of artificial vitreous humor utilizing polyacrylamide copolymers with disulfide crosslinkers." in American Chemical Society. (3 2006).

Patents

  • Salamone JC, Chen-Leung X, Salamone AB, Reilly KE. "Compositions for Enzymatic Debridement."
  • Salamone JC, Salamone AB, Reilly KE, Suggs LJ, Chung E, Leung KX-C. "Composition and Kits for Pseudoplastic Microgel Matrices."
  • Salamone,Joseph,Charles; Reilly,Katelyn,Elizabeth; Salamone,Ann,Beal; Chen,Xiaoyu. "Non-self-adherent coating materials." Patent number: 8877882
  • Salamone,Joseph,Charles; Chen,Xiaoyu; Salamone,Ann,Beal; Reilly,Katelyn,Elizabeth. "Delivery of biologically-active agents using volatile, hydrophobic solvents." Patent number: 8852648
  • Salamone JC, Reilly KE, Nixon RT, Salamone AB, Chen-Leung X.. "Composition and Kits for Inhibition of Pathogenic Microbial Infection and Methods of Using the Same."
  • Salamone JC, Salamone AB, Chen-Leung X, Reilly KE. "Compositions for Treating Pruritis."
  • Salamone JC, Chen-Leung X, Salamone AB, Reilly KE. "Compositions for Enzymatic Debridement." Patent number: 9592280