You are here

Sashwati Roy

  • Professor, General Surgery
  • Room #511
    473 W 12th Ave
    Columbus, OH 43210
  • 614-247-7657

Edited Books


  • Sashwati Roy, D Bagchi, SP Raychaudhury. 2012. "Chronic Inflammation: Molecular Pathophysiology, Nutrition and Therapteutic Interventions." Boca Raton: CRC.


  • Roy, S., Karenlampi, L., and Hanninen, O.. 1992. "7th International Bioindicators Symposium and Workshop on Environmental Health." Kuopio: Kuopio University Press.



  • Das A. and Roy S. 2015. "Micromanaging Inflammation and Tissue Repair." In MiRNA in Regenerative Medicine, edited by Sen CK, New York: Elsevier..
  • Das A., Chaffee S., Sen CK. and Roy S. 2015. "Wound Inflammation: Emerging role of miRNA in MicroRNAs and other non-coding RNAs in inflammation." In MicroRNAs and Other Non-Coding RNAs in Inflammation, edited by Greene C., New York: Springer..
  • Das A., Chaffee S. and Roy S.. 2015. "Genomics as a Tool to Characterize Anti-inflammatory Nutraceuticals." In Genomics, Proteomics and Metabolomics In Nutraceuticals & Functional Foods (2nd Edition), edited by Bagchi D., Swaroop A., Bagchi M., New Jersey: John Wiley & Sons.
  • Tewari AK., Mohanty S and Roy S. 2015. "Proteomics and Nutrition Research." In Genomics, Proteomics and Metabolomics In Nutraceuticals & Functional Foods (2nd Edition), edited by Bagchi D., Swaroop A., Bagchi M., New Jersey: John Wiley & Sons.


  • Das, A and Roy S. 2013. "Resolution of Inflammation." In Chronic Inflammation: Molecular Pathophysiology, Nutrition and Therapeutic Interventions, edited by Roy, S, Bagchi, D and Raychaudhuri, SP, New York: CRC Press.
  • Roy S., Das A. and Sen CK. 2013. "Disorder of localized inflammation in wound healing: a system's perspective." In Complex systems and computational biology approaches to acute inflammation, edited by Vodovotz Y., New York: Springer.


  • Sen, CK and Roy, S. 2012. "Wound Healing." In Plastic Surgery 3rd Edition Volume I: Principles, edited by Gurtner GC, Neligan PC, New York: Elsevier.


  • Roy S., Das A., Ganesh K. and Sen CK.. 2011. "Wound Inflammation: From Initiation to Resolution." In Inflammation, Lifestyle and Chronic Disease: The Silent link, edited by Aggarwal B B., Krishnan S., Guha S., New York: CRC press.


  • Sen, C.K. and Roy, S.. 2000. "Determination of nuclear factor-kB activity." In Models and Methods in Cell Signaling and Gene Expression: Applications to Oxidative Stress Research, edited by T.M. Bray and N. Schoene, Columbus: OICA International.


  • Roy, S. Sen, C.K., Gozin, A., Andrieu, V. and Pasquier, C.. 1999. "Redox Regulation of Cell Adhesion Processes." In Antioxidants and Redox Regulation of Genes, edited by C.K. Sen, H. Sies, P. Baeuerle, 265 - 295. San Diego: Academic Press.
  • Roy, S. Kobuchi, H., Sen, C.K. Dry-Lefaix, M-T. and Packer, L.. 1999. "Down-regulation of agonist-induced nitric oxide synthesis and cell-cell adhesion by Ginkgo biloba extract EGb 761: therapeutic efficacy in circulatory disorders." In Antioxidant Food Supplement in Human Health, edited by L. Packer, M. Hiramatsu, and T. Yoshikawa, 359 - 370. San Diego: Academic Press.
  • Sen, C.K., Roy, S., and Packer, L.. 1999. "Alpha-lipoic acid: cell regulatory function and potential implications." In Antioxidant Food Supplement in Human Health, edited by L. Packer, M. Hiramatsu, and T. Yoshikawa, 111 - 119. San Diego: Academic Press.


  • Sen, C.K., Roy, S., and Packer, L.. 1998. "Oxidants and Antioxidants in glutamate-induced cytotoxicity." In Biological Oxidants and Antioxidants: Molecular Mechanisms and Health Effects, edited by L. Packer and A.S.H., 5 - 13. Champaign: AOCS Press.
  • Roy, S., Kobuchi, H., Sen, C.K., Gohil, K., Droy-Lefaix, M-T., and Packer, L.. 1998. "Antioxidant properties and regulation of gene expression." In Ginkgo biloba extract: Lessons from Cell Biology, edited by L. Packer and Y. Christen, 5 - 13. A: Elseviar Science.


  • Sen, C. K., Roy, S., and Packer, L.. 1997. "Therapeutic potential of the antioxidant and redox properties of alpha-lipoic acid." In Oxidative stress cancer, AIDS and neurodegenerative diseases, edited by L. Montagnier, R. Oliver and C. Pasquier, 251 - 267. New York: Marcel Dekker Inc.
  • Packer, L., Roy, S., and Sen, C. K.. 1997. "Alpha-Lipoic acid: A metabolic antioxidant and potential redox modulator of transcription." In Advances in Pharmacology, edited by H. Sies, San Diego: Academic Press, Inc.


  • Sen, C.K., Roy, S., and Packer, L.. 1996. "Therapeutic potential of alpha-lipoic acid: molecular aspects." In Redox Regulation of Cell Signaling and its Clinical Applications. 3rd Internet World Congress on Biomedical Sciences, edited by T. Ohno, a: The Virtual Conference Hall.
  • Hanninen, O., Lindstrom-Seppa, P., Roy, S., and Huuskonen, S. 1996. "Fish and plant as experimental organisms: aquatic toxicology as an example." In Proceedings of the Symposium on Laboratory Animal Resource Development Experimentation and Welfare - which way to go?, hyderabad: a.
  • Tuvikene, A., Huuskonen, S., Roy, S., and Lindstrom-Seppa, P.. 1996. "Assessment of pollution using biotransformation enzymes in fish as biomarkers." In Proceedings of the 6th International Conference on the conversion and Management of lakes, Kasumiguara: a.
  • Roy, S., Lindstrom-Seppa, P., and Hanninen, O.. 1996. "Integrative approach to aquatic environment biomonitoring." In Environmental Xenobiotic, edited by M. Richardson, 123 - 142. London: Taylor & Friends.


  • Roy, S., and Hanninen, O.. 1995. "Macrophyte enzymes as indicators of aquatic pollution." In Bioindicators of Environmental Health, edited by M. Munawar, 45 - 53. Amsterdam: SPB Academic Publishing.
  • Roy, S., and Hanninen, O.. 1995. "Use of aquatic plants in ecotoxicology monitoring of organic pollutants: bioconcentration and biochemical responses." In Environmental Toxicology Assessment, edited by M. Richardson, 97 - 109. London: Taylor & Francis.
  • Munawar, M., Hanninen, O., Roy, S., Munawar, N., Karenlampi, L., and Brown, D.. 1995. "Bioindicators of Environmental Health." In Ecovision, edited by N. Munawar, 265 - Amsterdam: SPB Academic Publishing.
  • Roy, S., Lindstrom-Seppa, P., and Hanninen, O.. 1995. "Biotrasformation and antioxidant enzymes in aquatic organisms as bioindicators of pollution." In European Journal of Drug Metabolism and Pharmacokinetics, 49 - 51. a: Special Issue.


  • Roy, S., and Hanninen, O.. 1994. "Ortho- and para- hydroxylation of pentachlorophenol in aquatic plants: possible involvement of cytochrome P-450." In Proceedings of 8th International Conference on Cytochrome P-450, Biochemistry, Biophysics and Molecular Biology, edited by M. C. Lechner, 821 - 824. Paris: John Libbey Eurotext.


  • Roy, S., and Hanninen, O.. 1993. "Biochemical monitoring of the aquatic environment: Possibilities and limitations." In Ecotoxicology monitoring, edited by M. Richardson, 119 - 135. New York: VCH Publishers, Inc.
  • Roy, S., and Hanninen, O.. 1993. "Peroxidase activity in aquatic plants as a marker of aquatic pollution." In Biological Monitoring of the Environment, A Manual of Methods, edited by J. Salanki, D. Jeffrey and G. M. Hughes, 127 - 130. Oxon: CAB International in association with International Union of Biological Sciences (IUBS).
  • Roy, S., and Hanninen, O.. 1993. "Bioconcentration and metabolism of organic pollutants in aquatic plants." In Environmental Research in Finland Today. Proceedings of the First Finnish Conference of Environmental Sciences, edited by J. Tuomisto and J. Ruuskanen, 264 - 267. Kuopio: Kuopio University Publications.


  • Roy, S., and Hanninen, O.. 1992. "Biochemical Monitoring of the Aquatic Environment using Macrophytes." In Proceedings of the Symposium on the State of the Environment and Environmental monitoring in Northern Fennoscandia and the Kola Peninsula, edited by E. Tikkanen, M. Varmola and T. Katermaa, 158 - 160. Rovaniemi: Arctic Center Publications.


  • Sen, C. K., Roy, S., and Packer, L.. "Exercise induced oxidative stress and antioxidant nutrient." In International Olympic Committee Encyclopedia of Sports Medicine. Nutrition in Sports, edited by R. J. Maughan,

Journal Articles


  • Powers CJ, Dickerson R, Zhang SW, Rink C, Roy S, Sen CK, 2016, "Human cerebrospinal fluid microRNA: temporal changes following subarachnoid hemorrhage." Physiological Genomics 34, no. 2, 162 - 184.


  • Sinha,Mithun; Ghatak,Subhadip; Roy,Sashwati; Sen,Chandan,K, 2015, "microRNA-200b as a Switch for Inducible Adult Angiogenesis." ANTIOXIDANTS & REDOX SIGNALING 22, no. 14, 1257 - 1272.
  • Ghatak,Subhadip; Chan,Yuk,Cheung; Khanna,Savita; Banerjee,Jaideep; Weist,Jessica; Roy,Sashwati; Sen,Chandan,K, 2015, "Barrier Function of the Repaired Skin Is Disrupted Following Arrest if Dicer in Keratinocytes." MOLECULAR THERAPY 23, no. 7, 1201 - 1210.
  • Biswas,Ayan; Khanna,Savita; Roy,Sashwati; Pan,Xueliang; Sen,Chandan,K; Gordillo,Gayle,M, 2015, "Endothelial cell tumor growth is Ape/ref-1 dependent." AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 309, no. 5, C296 - C307.
  • Datta,Soma; Malhotra,Lavina; Dickerson,Ryan; Chaffee,Scott; Sen,Chandan,K; Roy,Sashwati, 2015, "Laser capture microdissection: Big data from small samples." HISTOLOGY AND HISTOPATHOLOGY 30, no. 11, 1255 - 1269.
  • Das,Amitava; Sinha,Mithun; Datta,Soma; Abas,Motaz; Chaffee,Scott; Sen,Chandan,K; Roy,Sashwati, 2015, "Monocyte and Macrophage Plasticity in Tissue Repair and Regeneration." AMERICAN JOURNAL OF PATHOLOGY 185, no. 10, 2596 - 2606.
  • Ghatak PD, Schlanger R, Ganesh K, Lambert L, Gordillo GM, Martinsek P, Roy S, 2015, "A Wireless Electroceutical Dressing Lowers Cost of Negative Pressure Wound Therapy." Advanced Wound Care (New Rochelle) 1, no. 4, 302 - 311.
  • Kim,Jayne,Y; Willard,James,J; Supp,Dorothy,M; Roy,Sashwati; Gordillo,Gayle,M; Sen,Chandan,K; Powell,Heather,M, 2015, "Burn Scar Biomechanics after Pressure Garment Therapy." PLASTIC AND RECONSTRUCTIVE SURGERY 136, no. 3, 572 - 581.
  • Ganesh K, Sinha M, Mathew-Steiner SS, Das A, Roy S, Sen CK, 2015, "Chronic Wound Biofilm Model." Advanced Wound Care (New Rochelle) 1, no. 4, 382 - 388.
  • Khanna,Savita; Das,Amitava; Spieldenner,James; Rink,Cameron; Roy,Sashwati, 2015, "Supplementation of a Standardized Extract from Phyllanthus emblica Improves Cardiovascular Risk Factors and Platelet Aggregation in Overweight/Class-1 Obese Adults." JOURNAL OF MEDICINAL FOOD 18, no. 4, 415 - 420.
  • Khanna,Savita; Heigel,Mallory; Weist,Jessica; Gnyawali,Surya; Teplitsky,Seth; Roy,Sashwati; Sen,Chandan,K; Rink,Cameron, 2015, "Excessive alpha-tocopherol exacerbates microglial activation and brain injury caused by acute ischemic stroke." FASEB JOURNAL 29, no. 3, 828 - 836.
  • Dickerson,Ryan; Banerjee,Jaideep; Rauckhorst,Adam; Pfeiffer,Douglas,R; Gordillo,Gayle,M; Khanna,Savita; Osei,Kwame; Roy,Sashwati, 2015, "Does Oral Supplementation of a Fermented Papaya Preparation Correct Respiratory Burst Function of Innate Immune Cells in Type 2 Diabetes Mellitus Patients?." ANTIOXIDANTS & REDOX SIGNALING 22, no. 4, 339 - 345.
  • Roy S, Sen CK, 2015, "Study of the human chronic wound tissue: addressing logistic barriers and productive use of laser capture microdissection." Methods Mol Biol 1037, 233 - 243.
  • Gnyawali,Surya,C; Barki,Kasturi,G; Mathew-Steiner,Shomita,S; Dixith,Sriteja; Vanzant,Daniel; Kim,Jayne; Dickerson,Jennifer,L; Datta,Soma; Powell,Heather; Roy,Sashwati; Bergdall,Valerie; Sen,Chandan,K, 2015, "High-Resolution Harmonics Ultrasound Imaging for Non-Invasive Characterization of Wound Healing in a Pre-Clinical Swine Model." PLOS ONE 10, no. 3, 3 -
  • Banerjee,Jaideep; Das Ghatak,Piya; Roy,Sashwati; Khanna,Savita; Hemann,Craig; Deng,Binbin; Das,Amitava; Zweier,Jay,L; Wozniak,Daniel; Sen,Chandan,K, 2015, "Silver-Zinc Redox-Coupled Electroceutical Wound Dressing Disrupts Bacterial Biofilm." PLOS ONE 10, no. 3, e0119531 -
  • Clemente-Vicario,Francisco; Alvarez,Carlos,E; Rowell,Jennie,L; Roy,Satavisha; London,Cheryl,A; Kisseberth,William,C; Lorch,Gwendolen, 2015, "Human Genetic Relevance and Potent Antitumor Activity of Heat Shock Protein 90 Inhibition in Canine Lung Adenocarcinoma Cell Lines." PLOS ONE 10, no. 11, e0142007 -


  • Elgharably,Haytham; Ganesh,Kasturi; Dickerson,Jennifer; Khanna,Savita; Abas,Motaz; Ghatak,Piya,Das; Dixit,Sriteja; Bergdall,Valerie; Roy,Sashwati; Sen,Chandan,K, 2014, "A modified collagen gel dressing promotes angiogenesis in a preclinical swine model of chronic ischemic wounds." WOUND REPAIR AND REGENERATION 22, no. 6, 720 - 729.
  • Das,Amitava; Ganesh,Kasturi; Khanna,Savita; Sen,Chandan,K; Roy,Sashwati, 2014, "Engulfment of Apoptotic Cells by Macrophages: A Role of MicroRNA-21 in the Resolution of Wound Inflammation." JOURNAL OF IMMUNOLOGY 192, no. 3, 1120 - 1129.
  • Roy,Sashwati; Elgharably,Haytham; Sinha,Mithun; Ganesh,Kasturi; Chaney,Sarah; Mann,Ethan; Miller,Christina; Khanna,Savita; Bergdall,Valerie,K; Powell,Heather,M; Cook,Charles,H; Gordillo,Gayle,M; Wozniak,Daniel,J; Sen,Chandan,K, 2014, "Mixed-species biofilm compromises wound healing by disrupting epidermal barrier function." JOURNAL OF PATHOLOGY 233, no. 4, 331 - 343.
  • Banerjee,Jaideep; Das Ghatak,Piya; Roy,Sashwati; Khanna,Savita; Sequin,Emily,K; Bellman,Karen; Dickinson,Bryan,C; Suri,Prerna; Subramaniam,Vish,V; Chang,Christopher,J; Sen,Chandan,K, 2014, "Improvement of Human Keratinocyte Migration by a Redox Active Bioelectric Dressing." PLOS ONE 9, no. 3, e89239 -
  • Gaughan A, Wang J, Pelletier RP, Nadasdy T, Brodsky S, Roy S, Lodder M, Bobek D, Mofatt-Bruce S, Fairchild RL, Henry ML, Hadley GA, 2014, "Key role for CD4 T cells during mixed antibody-mediated rejection of renal allografts." Am J Transplant 14, 284 - 294.
  • Gordillo,Gayle,M; Biswas,Ayan; Khanna,Savita; Pan,Xueliang; Sinha,Mithun; Roy,Sashwati; Sen,Chandan,K, 2014, "Dicer Knockdown Inhibits Endothelial Cell Tumor Growth via MicroRNA 21a-3p Targeting of Nox-4." JOURNAL OF BIOLOGICAL CHEMISTRY 289, no. 13, 9027 - 9038.
  • Gaughan A, Wang J, Pelletier RP, Nadasdy T, Brodsky S, Roy S, Lodder M, Bobek D, Mofatt-Bruce S, Fairchild RL, Henry ML, Hadley GA, 2014, "Key role for CD4 T cells during mixed antibody-mediated rejection of renal allografts." American Journal Transplant 14, 284 - 294.


  • Elgharably,Haytham; Roy,Sashwati; Khanna,Savita; Abas,Motaz; Dasghatak,Piya; Das,Amitava; Mohammed,Kareem; Sen,Chandan,K, 2013, "A modified collagen gel enhances healing outcome in a preclinical swine model of excisional wounds." WOUND REPAIR AND REGENERATION 21, no. 3, 473 - 481.
  • McDaniel JC, Roy S, Wilgus TA, 2013, "Neutrophil activity in chronic venous leg ulcers--a target for therapy?." Wound Repair Regeneration 21, 339 - 351.
  • Roy S, Sen CK, 2013, "Study of the human chronic wound tissue: addressing logistic barriers and productive use of laser capture microdissection." Methods of Molecular Biology 1037, 233 - 243.
  • Roy,Sashwati; Banerjee,Jaideep; Gnyawali,Surya,C; Khanna,Savita; He,Guanglong; Pfeiffer,Douglas; Zweier,Jay,L; Sen,Chandan,K, 2013, "Suppression of Induced microRNA-15b Prevents Rapid Loss of Cardiac Function in a Dicer Depleted Model of Cardiac Dysfunction." PLOS ONE 8, no. 6, e66789 -
  • Wilgus TA, Roy S, McDaniel JC, 2013, "Neutrophils and Wound Repair: Positive Actions and Negative Reactions." Advanced Wound Care 2, 379 - 388.
  • Hsu SH, Motiwala T, Roy S, Claus R, Mustafa M, Plass C, Freitas MA, Ghoshal K, Jacob ST, 2013, "Methylation of the PTPRO gene in human hepatocellular carcinoma and identification of VCP as its substrate." Journal of Cellular Biochemistry 114, 1810 - 1818.
  • Khanna,Savita; Rink,Cameron; Ghoorkhanian,Reza; Gnyawali,Surya; Heigel,Mallory; Wijesinghe,Dayanjan,S; Chalfant,Charles,E; Chan,Yuk,Cheung; Banerjee,Jaideep; Huang,Yue; Roy,Sashwati; Sen,Chandan,K, 2013, "Loss of miR-29b following acute ischemic stroke contributes to neural cell death and infarct size." JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 33, no. 8, 1197 - 1206.
  • Elgharably,Haytham; Mann,Ethan; Awad,Hamdy; Ganesh,Kasturi; Das Ghatak,Piya; Gordillo,Gayle; Sai-Sudhakar,Chittoor,B; Roy,Sashwati; Wozniak,Daniel,J; Sen,Chandan,K, 2013, "First Evidence of Sternal Wound Biofilm following Cardiac Surgery." PLOS ONE 8, no. 8, e70360 -
  • Willard,James,J; Drexler,Jason,W; Das,Amitava; Roy,Sashwati; Shilo,Shani; Shoseyov,Oded; Powell,Heather,M, 2013, "Plant-Derived Human Collagen Scaffolds for Skin Tissue Engineering." TISSUE ENGINEERING PART A 19, no. 13-14, 1507 - 1518.


  • Ganesh,Kasturi; Das,Amitava; Dickerson,Ryan; Khanna,Savita; Parinandi,Narasimham,L; Gordillo,Gayle,M; Sen,Chandan,K; Roy,Sashwati, 2012, "Prostaglandin E-2 Induces Oncostatin M Expression in Human Chronic Wound Macrophages through Axl Receptor Tyrosine Kinase Pathway." JOURNAL OF IMMUNOLOGY 189, no. 5, 2563 - 2573.
  • Chan,Yuk,Cheung; Roy,Sashwati; Huang,Yue; Khanna,Savita; Sen,Chandan,K, 2012, "The MicroRNA miR-199a-5p Down-regulation Switches on Wound Angiogenesis by Derepressing the v-ets Erythroblastosis Virus E26 Oncogene Homolog 1-Matrix Metalloproteinase-1 Pathway." JOURNAL OF BIOLOGICAL CHEMISTRY 287, no. 49, 41032 - 41043.
  • Shapiro,John,P; Biswas,Sabyasachi; Merchant,Anand,S; Satoskar,Anjali; Taslim,Cenny; Lin,Shili; Rovin,Brad,H; Sen,Chandan,K; Roy,Sashwati; Freitas,Michael,A, 2012, "A quantitative proteomic workflow for characterization of frozen clinical biopsies: Laser capture microdissection coupled with label-free mass spectrometry." JOURNAL OF PROTEOMICS 77, 433 - 440.
  • Dickerson,Ryan; Deshpande,Bhakthi; Gnyawali,Urmila; Lynch,Debbie; Gordillo,Gayle,M; Schuster,Dara; Osei,Kwame; Roy,Sashwati, 2012, "Correction of Aberrant NADPH Oxidase Activity in Blood-Derived Mononuclear Cells from Type II Diabetes Mellitus Patients by a Naturally Fermented Papaya Preparation." ANTIOXIDANTS & REDOX SIGNALING 17, no. 3, 485 - 491.
  • Yang,Fangping; Zhang,Xulang; Maiseyeu,Andrei; Mihai,Georgeta; Yasmeen,Rumana; Disilvestro,David; Maurya,Santosh,K; Periasamy,Muthu; Bergdall,K,Valerie; Gregg,Duester; Sen,Chandan,K; Roy,Sashwati; Lee,L,James; Rajagopalan,Sanjay; Ziouzenkova,Ouliana, 2012, "The prolonged survival of fibroblasts with forced lipid catabolism in visceral fat following encapsulation in alginate-poly-L-lysine." BIOMATERIALS 33, no. 22, 5638 - 5649.
  • Awad,Hamdy; Abas,Motaz; Elgharably,Haytham; Tripathi,Ravi; Theofilos,Tykie; Bhandary,Sujatha; Sai-Sudhakar,Chittoor; Sen,Chandan,K; Roy,Sashwati, 2012, "Endogenous Opioids in Wound-Site Neutrophils of Sternotomy Patients." PLOS ONE 7, no. 10, e47569 -
  • Roy,Sashwati; Sen,Chandan,K, 2012, "miRNA in Wound Inflammation and Angiogenesis." MICROCIRCULATION 19, no. 3, 224 - 232.
  • Chan,Yuk,Cheung; Roy,Sashwati; Khanna,Savita; Sen,Chandan,K, 2012, "Downregulation of Endothelial MicroRNA-200b Supports Cutaneous Wound Angiogenesis By Desilencing GATA Binding Protein 2 and Vascular Endothelial Growth Factor Receptor 2." ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 32, no. 6, 1372 - 1382.
  • Sen,Chandan,K; Roy,Sashwati, 2012, "OxymiRs in cutaneous development, wound repair and regeneration." SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY 23, no. 9, 971 - 980.
  • Patel,Viren; Rink,Cameron; Gordillo,Gayle,M; Khanna,Savita; Gnyawali,Urmila; Roy,Sashwati; Shneker,Bassel; Ganesh,Kasturi; Phillips,Gary; More,J,Layne; Sarkar,Atom; Kirkpatrick,Robert; Elkhammas,Elmahdi,A; Klatte,Emily; Miller,Michael; Firstenberg,Michael,S; Chiocca,E,Antonio; Nesaretnam,Kalanithi; Sen,Chandan,K, 2012, "Oral Tocotrienols Are Transported to Human Tissues and Delay the Progression of the Model for End-Stage Liver Disease Score in Patients." JOURNAL OF NUTRITION 142, no. 3, 513 - 519.


  • Park,Han-A; Kubicki,Natalia; Gnyawali,Surya; Chan,Yuk,Cheung; Roy,Sashwati; Khanna,Savita; Sen,Chandan,K, 2011, "Natural Vitamin E alpha-Tocotrienol Protects Against Ischemic Stroke by Induction of Multidrug Resistance-Associated Protein 1." STROKE 42, no. 8, 2308 - U450.
  • Roy,Sashwati; Dickerson,Ryan; Khanna,Savita; Collard,Eric; Gnyawali,Urmila; Gordillo,Gayle,M; Sen,Chandan,K, 2011, "Particulate beta-glucan induces TNF-alpha production in wound macrophages via a redox-sensitive NF-kappa beta-dependent pathway." WOUND REPAIR AND REGENERATION 19, no. 3, 411 - 419.
  • Roy,Sashwati; Sen,Chandan,K, 2011, "MiRNA in innate immune responses: novel players in wound inflammation." PHYSIOLOGICAL GENOMICS 43, no. 10, 557 - 565.
  • Christoforidis,Gregory,A; Rink,Cameron; Kontzialis,Marinos,S; Mohammad,Yousef; Koch,Regina,M; Abduljalil,Amir,M; Bergdall,Valerie,K; Roy,Sashwati; Khanna,Savita; Slivka,Andrew,P; Knopp,Michael,V; Sen,Chandan,K, 2011, "An Endovascular Canine Middle Cerebral Artery Occlusion Model for the Study of Leptomeningeal Collateral Recruitment." INVESTIGATIVE RADIOLOGY 46, no. 1, 34 - 40.
  • Roy,Sashwati; Driggs,Jason; Elgharably,Haytham; Biswas,Sabyasachi; Findley,Muna; Khanna,Savita; Gnyawali,Urmila; Bergdall,Valerie,K; Sen,Chandan,K, 2011, "Platelet-rich fibrin matrix improves wound angiogenesis via inducing endothelial cell proliferation." WOUND REPAIR AND REGENERATION 19, no. 6, 753 - 766.
  • Chan,Yuk,Cheung; Khanna,Savita; Roy,Sashwati; Sen,Chandan,K, 2011, "miR-200b Targets Ets-1 and Is Down-regulated by Hypoxia to Induce Angiogenic Response of Endothelial Cells." JOURNAL OF BIOLOGICAL CHEMISTRY 286, no. 3, 2047 - 2056.


  • Roy,Sashwati; Khanna,Savita; Azad,Ali; Schnitt,Rebecca; He,Guanglong; Weigert,Cora; Ichijo,Hidenori; Sen,Chandan,K, 2010, "Fra-2 mediates oxygen-sensitive induction of transforming growth factor beta in cardiac fibroblasts." CARDIOVASCULAR RESEARCH 87, no. 4, 647 - 655.
  • Collard,Eric; Roy,Sashwati, 2010, "Improved Function of Diabetic Wound-Site Macrophages and Accelerated Wound Closure in Response to Oral Supplementation of a Fermented Papaya Preparation." ANTIOXIDANTS & REDOX SIGNALING 13, no. 5, 599 - 606.
  • Collard E, Roy S, 2010, "Improved function of diabetic wound-site macrophages and accelerated wound closure in response to oral supplementation of a fermented papaya preparation." Antioxidant Redox Signal 13, 599 - 606.
  • Maiseyeu A, Mihai G, Roy S, Kherada N, Simonetti OP, Sen CK, Sun Q, Parthasarathy S, Rajagopalan S, 2010, "Detection of macrophages via paramagnetic vesicles incorporating oxidatively tailored cholesterol ester: an approach for atherosclerosis imaging." Nanomedicine 5, 1341 - 1356.
  • Rink,Cameron; Roy,Sashwati; Khan,Mahmood; Ananth,Pavan; Kuppusamy,Periannan; Sen,Chandan,K; Khanna,Savita, 2010, "Oxygen-sensitive outcomes and gene expression in acute ischemic stroke." JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 30, no. 7, 1275 - 1287.
  • Biswas,Sabyasachi; Roy,Sashwati; Banerjee,Jaideep; Hussain,Syed-Rehan,A; Khanna,Savita; Meenakshisundaram,Guruguhan; Kuppusamy,Periannan; Friedman,Avner; Sen,Chandan,K, 2010, "Hypoxia inducible microRNA 210 attenuates keratinocyte proliferation and impairs closure in a murine model of ischemic wounds." PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 107, no. 15, 6976 - 6981.
  • Sliman,Sean,M; Eubank,Timothy,D; Kotha,Sainath,R; Kuppusamy,M,Lakshmi; Sherwani,Shariq,I; Butler,Elizabeth,Susan O'Connor; Kuppusamy,Periannan; Roy,Sashwati; Marsh,Clay,B; Stern,David,M; Parinandi,Narasimham,L, 2010, "Hyperglycemic oxoaldehyde, glyoxal, causes barrier dysfunction, cytoskeletal alterations, and inhibition of angiogenesis in vascular endothelial cells: aminoguanidine protection." MOLECULAR AND CELLULAR BIOCHEMISTRY 333, no. 1-2, 9 - 26.
  • Khanna,Savita; Parinandi,Narasimham,L; Kotha,Sainath,R; Roy,Sashwati; Rink,Cameron; Bibus,Douglas; Sen,Chandan,K, 2010, "Nanomolar vitamin E alpha-tocotrienol inhibits glutamate-induced activation of phospholipase A(2) and causes neuroprotection." JOURNAL OF NEUROCHEMISTRY 112, no. 5, 1249 - 1260.
  • Khanna,Savita; Biswas,Sabyasachi; Shang,Yingli; Collard,Eric; Azad,Ali; Kauh,Courtney; Bhasker,Vineet; Gordillo,Gayle,M; Sen,Chandan,K; Roy,Sashwati, 2010, "Macrophage Dysfunction Impairs Resolution of Inflammation in the Wounds of Diabetic Mice." PLOS ONE 5, no. 3, e9539 -
  • Gordillo,Gayle; Fang,Huiqing; Park,Hana; Roy,Sashwati, 2010, "Nox-4-Dependent Nuclear H2O2 Drives DNA Oxidation Resulting in 8-OHdG as Urinary Biomarker and Hemangioendothelioma Formation." ANTIOXIDANTS & REDOX SIGNALING 12, no. 8, 933 - 943.
  • Patt,Brian,T; Jarjoura,David; Lambert,Lynn; Roy,Sashwati; Gordillo,Gayle; Schlanger,Richard; Sen,Chandan,K; Khayat,Rami,N, 2010, "Prevalence of Obstructive Sleep Apnea in Patients with Chronic Wounds." JOURNAL OF CLINICAL SLEEP MEDICINE 6, no. 6, 541 - 544.
  • Sen CK, Roy S, 2010, "Oxygenation state as a driver of myofibroblast differentiation and wound contraction: hypoxia impairs wound closure." J Invest Dermatology 130, 2701 - 2703.
  • Patt,Brian,T; Jarjoura,David; Haddad,Diane,N; Sen,Chandan,K; Roy,Sashwati; Flavahan,Nicholas,A; Khayat,Rami,N, 2010, "Endothelial Dysfunction in the Microcirculation of Patients with Obstructive Sleep Apnea." AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 182, no. 12, 1540 - 1545.


  • Li,Zhenqing; Wang,Feng; Roy,Sashwati; Sen,Chandan,K; Guan,Jianjun, 2009, "Injectable, Highly Flexible, and Thermosensitive Hydrogels Capable of Delivering Superoxide Dismutase." BIOMACROMOLECULES 10, no. 12, 3306 - 3316.
  • Gnyawali,Surya,C; Roy,Sashwati; Mccoy,Molly; Biswas,Sabyasachi; Sen,Chandan,K, 2009, "Remodeling of the Ischemia-Reperfused Murine Heart: 11.7-T Cardiac Magnetic Resonance Imaging of Contrast-Enhanced Infarct Patches and Transmurality." ANTIOXIDANTS & REDOX SIGNALING 11, no. 8, 1829 - 1839.
  • Conlisk AT, Datta S, Fissell WH, Roy S, 2009, "Biomolecular transport through hemofiltration membranes." Ann Biomed Eng 37, 722 - 736.
  • Li Z, Wang F, Roy S, Sen CK, Guan J, 2009, "Injectable, highly flexible, and thermosensitive hydrogels capable of delivering superoxide dismutase." Biomacromolecules 10, 3306 - 3316.
  • Sen CK, Gordillo GM, Roy S, Kirsner R, Lambert L, Hunt TK, Gottrup F, Gurtner GC, Longaker MT, 2009, "Human skin wounds: a major and snowballing threat to public health and the economy." Wound Repair Regeneration 17, 763 - 771.
  • Sen CK, Gordillo GM, Khanna S, Roy S, 2009, "Micromanaging Vascular Biology: Tiny MicroRNAs Play Big Band." J Vasc Res 46, 527 - 540.
  • Roy, S; Biswas, S; Khanna, S; Gordillo, G; Bergdall, V; Green, J; Marsh, CB; Gould, LJ; Sen, CK, 2009, "Characterization of a preclinical model of chronic ischemic wound." Physiological Genomics 37, no. 3, 211 - 224.
  • Roy, S; Khanna, S; Hussain, SR; Biswas, S; Azad, A; Rink, C; Gnyawalu, S; Shilo, S; Nuovo, GJ; Sen, Ck, 2009, "MicroRNA expression in response to murine myocardial infarcation: miR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue." Cardiovascular Resarch 82, no. 1, 21 - 29.
  • Gnyawali, SC; Roy, S; McCoy, M; Biswas, S; Sen, CK, 2009, "Remodeling of the ischemia-reperfused murine heart." Antioxidants & Redox Signaling 11, 1829 - 1839.
  • Park, HA; Khanna ,S; Rink, C; Gnyawali, S; Roy, S; Sen, CK, 2009, "Glutathione disulfide induces neural cell death via a 12-lipoxygenase pathway." Cell Death & Differentiation 16, 1167 - 1179.
  • Atalay, M; Oksala, N; Lappalaine, J; Laaksonen, DE; Sen, CK; Roy, S, 2009, "Heat shock proteins in diabetes and wound healing." Protein & Peptide Science 10, 85 - 95.


  • Gordillo GM, Roy S, Khanna S, Schlanger R, Khandelwal S, Phillips G, Sen CK, 2008, "Topical oxygen therapy induces vascular endothelial growth factor expression and improves closure of clinically presented chronic wounds." Clin Exp Pharmacol 35, 957 - 964.
  • Venkatakrishnan,C,D; Dunsmore,Kathy; Wong,Hector; Roy,Sashwathi; Sen,Chandan,K; Wani,Altaf; Zweier,Jay,L; Ilangovan,Govindasamy, 2008, "HSP27 regulates p53 transcriptional activity in doxorubicin-treated fibroblasts and cardiac H9c2 cells: p21 upregulation and G(2)/M phase cell cycle arrest." AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 294, no. 4, H1736 - H1744.
  • Shilo S, Roy S, Khanna S, Sen CK, 2008, "Evidence for the involvement of miRNA in redox regulated angiogenic response of human microvascular endothelial cells." Arterioscler Thromb Vasc Biol 28, 471 - 477.
  • Roy,Sashwati; Ojha,Navdeep; He,Guanglong; Biswas,Sabyasachi; Velayutham,Murugesan; Khanna,Savita; Kuppusamy,Periannan; Zweier,Jay,L; Sen,Chandan,K, 2008, "Rac2 in redox regulated wound healing." WOUND REPAIR AND REGENERATION 16, no. 2, A13 - A13.
  • Ramaswamy B, Majumder S, Roy S, Ghoshal K, Kutay H, Datta J, Younes M, Shapiro CL, Motiwala T, Jacob ST, 2008, "Estrogen-mediated suppression of the gene encoding protein tyrosine phophatase PTPRO in human breast cancer: mechanism and role in tamoxifen sensitivity." Molecular Endocrinology 23, 176 - 187.
  • Roy S, Khanna S, Sen CK, 2008, "Redox regulation of the VEGF signaling path and tissue vascularization: Hydrogen peroxide, the common link between physical exercise and cutaneous wound healing." Free Radic Biol Med 44, 180 - 192.
  • Sen CK, Roy S., 2008, "Redox signals in wound healing." Biochim Biophys Acta 1780, 1348 - 1361.
  • Rink C; Christoforidis G; Abduljalil A; Kontzialis M; Bergdall V; Roy S; Khanna S; Slivka A; Knopp M; Sen CK, 2008, "Minimally invasive neuroradiologic model of preclinical transient middle cerebral artery occlusion in canines.." Proceedings Of The National Academy Of Sciences Of The United States Of America 105, no. 37, 14100 - 14105.
  • Maiseyeu, A; Milhai, G; Kampfrath, T; Simonetti, OP; Sen, CK; Roy, S; Rajagopalan, S; Parthasarathy, S, 2008, "Gadolinium containing phosphatidylserine liposomes for molecular imaging of athersclerosis." Journal of Lipid Research 50, 2157 - 2163.
  • Khanna, S; Park, HA; Sen, CK; Golakoti, T; Sengupta, K; Venkateswarlu, S; Roy, S, 2008, "Neuroprotective and anti-inflammatory properties of a novel demethylated curcuminoid." Antioxidants & Redox Signaling 11, 449 - 468.


  • Sen CK, Khanna S, Rink C, Roy S, 2007, "Tocotrienols: the emerging face of natural vitamin E." Vitam Horm 76, 203 - 61.
  • Shilo S, Roy S, Khanna S, Sen CK, 2007, "MicroRNA in cutaneous wound healing: a new paradigm." DNA Cell Biol 26, no. 4, 227 - 37.
  • Sen CK, Khanna S, Roy S, 2007, "Tocotrienols in health and disease: The other half of the natural vitamin E family." Mol Aspects Med 28, 692 - 728.
  • Ioshikhes I, Roy S, Sen CK, 2007, "Algorithms for mapping of mRNA targets for microRNA." DNA Cell Biol 26, 265 - 272.
  • Ratan RR, Siddiq A, Smirnova N, Karpisheva K, Haskew-Layton R, McConoughey S, Langley B, Estevez A, Huerta PT, Volpe B, Roy S, Sen CK, Gazaryan I, Cho S, Fink M, LaManna J., 2007, "Harnessing hypoxic adaptation to prevent, treat, and repair stroke." J Mol Med 85, 1331 - 1338.


  • Sen CK, Khanna S, Roy S, 2006, "Perceived hyperoxia: oxygen-induced remodeling of the reoxygenated heart." Cardiovasc Res 71, no. 2, 280 - 8.
  • Roy S, Sen CK, 2006, "cDNA microarray screening in food safety." Toxicology 221, no. 1, 128 - 33.
  • Verducci JS, Melfi VF, Lin S, Wang Z, Roy S, Sen CK, 2006, "Microarray analysis of gene expression: considerations in data mining and statistical treatment." Physiol Genomics 25, no. 3, 355 - 63.
  • Sen CK, Khanna S, Roy S, 2006, "Tocotrienols: Vitamin E beyond tocopherols." Life Sci 78, no. 18, 2088 - 98.


  • Roy S, Sen CK, 2005, "Relief from a heavy heart: redox-sensitive NF-kB as a therapeutic target in managing cardiac hypertrophy." Am J Physiol Heart Circ Physiol 289, no. 1, H17 - 9.
  • Khanna,S; Roy,S; Slivka,A; Craft,T,KS; Chaki,S; Rink,C; Notestine,M,A; DeVries,A,C; Parinandi,N,L; Sen,C,K, 2005, "Neuroprotective properties of the natural vitamin E alpha-tocotrienol." STROKE 36, no. 10, 2258 - 2264.


  • Liu-Stratton, Y, Roy S., Sen C.K., 2004, "DNA microarray technology in neutraceutical and food safety." Toxicology Letters 150, 29 - 42.
  • Roy S, Khanna S, Sen CK, 2004, "Tocotrienol the natural vitamin E to defend the nervous system." NY Academy of Science 1031, 127 - 142.


  • Sen CK, Khanna S, Gordillo G, Bagchi D, Bagchi M, Roy S., 2002, "Oxygen, oxidants, and antioxidants in wound healing: an emerging paradigm." Ann N Y Acad Sci 957, 239 - 49.


  • Roy, S; Venojarvi, M; Khanna, S; Sen, CK, 2001, "Simultaneous detection of tocopherols and tocotrienols in biological samples using HPLC-coulometric electrode array." Meth Enzymol 352, 326 - 332.
  • Lindstrom-Seppa P, Urban K, Honkalampi-Hamalainen U, Roy S, 2001, "Biochemical responses in aquatic plants as markers of environmental contamination." Altern Lab Anim 29, 277 - 282.
  • Sen CK, Roy S, 2001, "Antioxidant regulation of cell adhesion." Med Sci Sports Exerc 33, 377 - 381.
  • Yannone, SM; Roy, S; Chan, DW; Murphy, MB; Huang, S; Campisi, J; Chen. DJ, 2001, "Werner syndrome protein is regulated and phosphorylated by DNA-dependent protein kinase." The Journal of Biological Chemistry 276, no. 41, 38242 - 38248.
  • Sen, CK; Roy, S, 2001, "Redox control of caspases." Environmental Toxicology and Pharmacology 10, 215 - 220.
  • Khanna, S; Roy, S; Bagchi, D; Bagch, M; Sen. CK, 2001, "Upregulation of oxidant-induced VEGF expression in cultured keratinocytes by a grape seed proanthocyanidin extract." Free Radical Biology & Medicine 31, no. 1, 38 - 42.


  • Tirosh, O; Sen, CK; Roy, S; Packer, L, 2000, "Cellular and mitochondrial changes in glutamate-induced HT4 neuronal cell death." Neuroscience 97, no. 3, 531 - 541.
  • Bito, T; Roy, S; Sen, CK, 2000, "Pine bark extract pycnogenol down-regulates IFNg-induced adhesion of T-cells to human keratinocytes by inhibiting inducible ICAM-1 expression." Free Radic Biol Med 28, 219 - 227.
  • Sen, CK; Khanna, S; Roy, S; Packer, L, 2000, "Molecular basis of vitamin E action: tocotrienol potently inhibits glutamate-induced pp60(c-src) kinase activation and death of HT4 neuronal cells." J Biol Chem 275, 13049 - 13055.


  • Kobuchi, H; Roy, S; Sen, CK; Nguyen, HG; Packer, L, 1999, "Quercetin inhibits inducible ICAM-1 espression in human endothelial cells through the JNK pathway." Am. J Physiol (Cell) 277, C403 - 411.
  • Sen, CK; Roy, S; Packer, L, 1999, "Redox regulation of Fas receptor mediated apoptosis of human Jurkat T-cells." Cell Death and Differentiation 6, 481 - 491.
  • Viita, H; Sen, CK; Roy, S; Siljamaki, T; Nikkari, T; Yla-Herttuala, 1999, "High expression of 15-lipoxygenase induces NF-kB mediated espression of vascular cell adhesion molecule 1, intercellular adhesion molecule-1 and T-cell adhesion on human endothelial cells." Antiox Redox Signal 1, 83 - 96.
  • Gohil, K; Roy, S; Packer, L; Sen, CK, 1999, "Antioxidant regulation of gene expression: analysis of differentially expressed mRNAs." Methods Enzymol 300, 402 - 410.
  • Tirosh, O; Sen, Ck; Roy, S; Kobayashi, M; Packer, L, 1999, "Neuroprotective effects of alpha lipoic acid and its positively charged amide analogue." Free Radic Biol Med 26, 1418 - 1426.
  • Roy, S; Sen, CK, Packer, L, 1999, "Determination of cell-cell adhesion in response to oxidants and antioxidants." Methods Enzymol 300, 395 - 401.
  • Khanna, S; Atalay, M; Laaksonen, DE; Gul, M; Roy, S; Sen, CK, 1999, "Alpha-lipoic acid supplementation: tissue glutathione homeostasis at rest and after exercise." J Appl Physiol 86, no. 4, 1191 - 1196.
  • Khanna, S; Roy, S; Packer, L; Sen, CK, 1999, "Cytokine-induced glucose uptake in skeletal muscle: redox regulation and the role of alpha-lipoic acid." Am. J. Physiol. 276, R1327 - 1333.
  • Sen, CK; Roy, S; Packer, L, 1999, "Flow cytometric determination of cellular thiols." Methods Enzymol 299, 247 - 258.
  • Sen, Ck; Roy, S; Khanna, S; Packer, L, 1999, "Determination of oxidized and reduced lipoic acid using high-performance liquid chromatography and coulometric detection." Methods Enzymol 299, 239 - 246.
  • Rimbach, G; Hohler, D; Fischer, A; Roy, S; Virgili, F; Pallauf, J; Packer, L, 1999, "Methods to assess free radicals and oxidative stress in biological systems." Arch Tierernahr 52, no. 3, 203 - 22.


  • Roy, S; Packer, L, 1998, "Redox regulation of cell functions by alpha-lipoate: biochemical and molecular aspects." Biofactors 8, 17 - 21.
  • Roy, S; Sen, CK; Kobuchi, H; Packer, L, 1998, "Antioxidant regulation of phorbol ester-induced adhesion of human Jurkat T-cells to endothelial." Free Radic Biol Med 25, 229 - 41.
  • Khanna S, Atalay M, Lodge JK, Laaksonen DE, Roy S, Hanninen O, Packer L, Sen CK, 1998, "Skeletal muscle and liver lipoyllysine content in response to exercise, training and dietary alpha-lipoic acid supplementation." Biochem Mol Biol Int. 46, 297 - 306.
  • Khanna, S., Sen, C. K., Roy, S., Christen, M. O., and Packer, L., 1998, "Protective effects of anethole dithiolethione against oxidative stress- induced cytotoxicity in human Jurkat T cells." Biochem Pharmacol 56, 61 - 9.
  • Sen, C. K., Tirosh, O., Roy, S., Kobayashi, M. S., and Packer, L., 1998, "A positively charged alpha-lipoic acid analogue with increased cellular uptake and more potent immunomodulatory activity." Biochem Biophys Res Commun 247, 223 - 8.


  • Ogino, T., Kobuchi, H., Sen, C. K., Roy, S., Packer, L., and Maguire, J. J., 1997, "Monochloramine inhibits phorbol ester-inducible neutrophil respiratory burst activation and T cell interleukin-2 receptor expression by inhibiting inducible protein kinase C activity." J Biol Chem 272, 26247 - 52.
  • Sen, C. K., Roy, S., Han, D., and Packer, L., 1997, "Regulation of cellular thiols in human lymphocytes by alpha-lipoic acid: A flow cytometric analysis." Free Radic Biol Med 22, 1241 - 1257.
  • Korcheva, J., Roy, S., Vranjic, J. A., Haukioja, E., Hughes, P. R., and Hanninen, O., 1997, "Antioxidant responses to simulated acid rain and heavy metal deposition in birch seedlings." Environ Pollut 95, 249 - 258.
  • Schroder, P., Juuti, S., Roy, S., Sandermann, H., and Sutinen, S., 1997, "Responses of peroxidase and glutathione S-transferase activity in pine needles on the exposure to chlorinated acetic acid." Environ Sci Pollut Res 4, 163 - 7.
  • Packer L, Roy S, Sen CK, 1997, "Alpha-lipoic acid: a metabolic antioxidant and potential redox modulator of transcription." Adv Pharmacol 38, 79 - 101.
  • Han, D., Sen, C. K., Roy, S., Kobayashi, M. S., Tritschler, H. J., and Packer, L., 1997, "Protection against glutamate-induced cytotoxicity in C6 glial cells by thiol antioxidants." Am J Physiol 273, R1771 - R1771.
  • Sen, C. K., Khanna, S., Reznick, A. Z., Roy, S., and Packer, L., 1997, "Glutathione regulation of tumor necrosis factor-alpha-induced NF-kappa B activation in skeletal muscle-derived L6 cells." Biochem Biophys Res Commun 237, 645 - 9.
  • Viskari EL, Rekila R, Roy S, Lehto O, Ruuskanen J, Karenlampi L, 1997, "Airborne pollutants along a roadside: assessment using snow analyses and moss bags." Environ Pollut 97, no. 1-2, 153 - 60.
  • Han, D., Handelman, G., Marcocci, L., Sen, C. K., Roy, S., Kobuchi, H., Tritschler, H. J., Flohe, L., and Packer, L., 1997, "Lipoic acid increases de novo synthesis of cellular glutathione by improving cystine utilization." Biofactors 6, 321 - 38.
  • Sen, C. K., Atalay, M., Agren, J., Laaksonen, D. E., Roy, S., and Hanninen, O., 1997, "Fish oil and vitamin E supplementation in oxidative stress at rest and after physical exercise." J Appl Physiol 83, 189 - 195.
  • Roy, S., Sen, C. K., Tritschler, H. J., and Packer, L., 1997, "Modulation of cellular reducing equivalent homeostasis by alpha-lipoic acid. Mechanisms and implications for diabetes and ischemic injury." Biochem Pharmacol 53, 393 - 9.


  • Sen, C. K., Roy, S., and Packer, L., 1996, "Involvement of intracellular Ca-2+ in oxidant-induced NF-kappa-B activation." FEBS Letters 385, 58 - 62.
  • Huskonen, S., Lindstrom-Seppa, P., Koponen, K., and Roy, S., 1996, "Effects of non-ortho-substituted polychlorinated biphenyls (congeners 77 and 126) on cytochrome P4501A and conjugation activities in rainbow trout (Oncorhynchus mykiss)." Comp Biochem Physiol C 113, 205 - 213.
  • Roy, S., Sen, C. K., and Hanninen, O., 1996, "Monitoring of polycyclic aromatic hydrocarbons using 'moss bags': Bioaccumulation and responses of antioxidant enzymes in Fontinalis antipyretica Hedw." Chemosphere 32, 2305 - 2315.
  • Panigrahi, M., Sadguna, Y., Shivakumar, B. R., Kolluri, S. V. R., Roy, S., Packer, L., and Ravindranath, V., 1996, "Alpha-Lipoic acid protects against reperfusion injury following cerebral ischemia in rats." Brain Res 717, 184 - 188.
  • Lindstrom-Seppa, P., Roy, S., Huuskonen, S., Tossavainen, K., Ritola, O., and Marin, E., 1996, "Biotransformation and glutathione homeostasis in rainbow trout exposed to chemical and physical stress." Mar Environ Res 42, 323 - 327.
  • Tuomainen, J., Pellinen, R., Roy, S., Kiiskinen, M., Eloranta, T., Karjalainen, R., and Kangasjarvi, J., 1996, "Ozone affects birch (Betula pendula Roth) phenylpropanoid, polyamine and active oxygen detoxifying pathways at biochemical and gene expression level." J Plant Physiol 148, 179 - 188.
  • Tuvikene, A., Huuskonen, S., Roy, S., and Lindstrom-Seppa, P., 1996, "Biomonitoring of South Estonian waters by means of xenobiotic metabolism of rainbow trout (Onchorynchus mykiss)." Comp Biochem Physiol 114C, 171 - 177.


  • Roy, S., Noda, Y., Eckert, V., Traber, M. G., Mori, A., Liburdy, R., and Packer, L., 1995, "The phorbol 12-myristate 13-acetate (PMA)-induced oxidative burst in rat peritoneal neutrophils is increased by a 0.1 mT (60 Hz) magnetic field." FEBS Letters 376, 164 - 166.
  • Roy S, Lindstrom-Seppa P, Huuskonen S, Hanninen O., 1995, "Responses of biotransformation and antioxidant enzymes in Lemna minor and Oncorhynchus mykiss exposed simultaneously to hexachlorobenzene." Chemosphere 30, 1489 - 1498.


  • Roy, S., and Hanninen, O., 1994, "Pentachlorophenol: Uptake-elimination kinetics and metabolism in an aquatic plant, Eichhornia crassipes." Environ Toxicol Chem 13, 763 - 773.
  • Roy, S., Pellinen, J., Sen, C. K., and Hanninen, O., 1994, "Benzo(a)anthracene and benzo(a)pyrene exposure in the aquatic plant: Fontinalis antipyretica: Uptake, elimination and the responses of biotransformation and antioxidant enzymes." Chemosphere 29, 1301 - 1311.
  • Talvinen, J., Pellinen, R., Roy, S., Eloranta, T., Julkunen-Tiitto, R., and Kangasjarvi, J., 1994, "Ozone induction of birch (Betula pendula Roth) defense mechanisms at biochemical and gene expression level." Biologia Plantarum (Prague) 36, S358 -


  • Roy, S., Ihantola, R., and Hanninen, O., 1992, "Peroxidase Activity in Lake Macrophytes and Its Relation to Pollution Tolerance." Environ Exp Bot 32, 457 - 464.


  • "a." 2008, Presented at Wound Healing Society,
  • "Annual meeting." 2008, Presented at American College of Nutrition, Arlington, US|USA
  • "Reoxygenation-Induced Myocardial Remodeling." 2004, Presented at Burke Medical Research Institute, White Plains, US|USA
  • "a." 2008, Presented at Society for Free Radical Research, Jaipur, IN|IND
  • "Scientist seminar." 2008, Presented at Institute for Environmental Medicine,
  • "TRENDS: Traditional and Progress." 2009, Presented at TRENDS: Traditional and Progress, US|USA
  • "Meeting." 2009, Presented at Wound Healing Society,
  • "Podium presentation." 2010, Presented at SAWC/WHS, Dallas, US|USA
  • "Tocotrienols." 2010, Presented at 1st International Conference on Tocotrenols and Chronic Diseases, Las Vegas, US|USA
  • "Workshop." 2010, Presented at Biomedical Resources Workshop, Columbus, US|USA
  • "Wound Care." 2011, Presented at 4th Annual Translation to Clinical (T2C) Wound Care Conference, Columbus,
  • "Podium presentation." 2011, Presented at SAWC/WHS, Dallas, US|USA
  • "Redox Biology and Micronutrients: from signaling translation and back." 2011, Presented at SFRR, Instanbul,
  • "Lecture." 2011, Presented at FEPS, Instanbul, TR|TUR
  • "Joint Meeting." 2011, Presented at Joint Meeting of the ESM and GfMVB, Munich, DE|DEU
  • "Scientific Sessions." 2011, Presented at AHA Scientific Sessions, Orlando,
  • "Wound Healing." 2011, Presented at 12th Annual Wound Healing: Science and Industry, PR|PRI
  • "Regenerative Wound Care." 2012, Presented at Fifth Annual Translational to Clinical (T2C) Regenerative Medicine Wound Care Conference,
  • "Biochemitry Seminar." 2012, Presented at LSUHSC - School of Medicine in Shreveport,
  • "Meeting." 2012, Presented at Symposium on Advanced Wound Care and Healing Society,
  • "Heart Rhythym." 2012, Presented at The Society's 33rd Annual Scientific Sessions, Boston,
  • "Endocrinology." 2012, Presented at Endocrinology Grand Rounds, Columbus,
  • "Society for Free Radial Research." 2012, Presented at 16th SFRRI Conference, London, GB|GBR
  • "Wound Healing and Tissue Repair." 2013, Presented at American College of Wound Healing and Tissue Repair Annual Mg, Chicago, US|USA
  • "Wound Care." 2015, Presented at Wound Care Big Data Summit, Bethesda, US|USA
  • "Impact on Health Wellness, Environment and Economics." 2015, Presented at Translational Sciece and Drug Discovery, Balaclava,
  • "Diabetes." 2012, Presented at Global Diabetes Summit, Columbus, US|USA
  • "Anesthesia Research." 2012, Presented at Department of Anesthesia Research Meeting, Columbus,
  • "Health." 2013, Presented at FAV Health, Dharwad, IN|IND
  • "Organizing Committee." 2013, Presented at Annual Translational to Clinical (T2C), Regenerative Medicine,
  • "Workshop." 2013, Presented at Trans-NIH Aniogenesis Workshop, Bethesda,
  • "Wound Care and Wound Healing." 2013, Presented at Symposium on Advanced Wound Care and Wound Healing Society,
  • "Advanced Wound Care and Wound Healing Society." 2013, Presented at WHS track at Symposium on Advanced Wound Care and Wound Healing Society,
  • "Annual Retreat." 2013, Presented at 2nd Annual Retreat of CRMCBT,
  • "Experimental Biology." 2014, Presented at Experimental Biology - AAA, San Diego, US|USA
  • "Wound Healing." 2014, Presented at Wound Healing: Science & Industry, San Juan, PR|PRI
  • "Annual Meeting." 2014, Presented at IFT Annual Meeting, New Orleans, US|USA
  • "Strategic Meeting." 2014, Presented at WHS, Atlanta, US|USA
  • "H3C." 2015, Presented at H3C Conference, Mumbai, IN|IND
  • "Chronic Wound Care." 2015, Presented at Chronic Wound Care, Kolkata, IN|IND
  • "Wound Care and Wound Healing." 2015, Presented at Symposium on Advanced Wound Care and Wound Healing Society,
  • "Shock." 2015, Presented at Annual Shock Society Meeting, Denver, US|USA
  • "Inflammation and Health." 2015, Presented at International Symposium on Inflammation and Health, Orlando, US|USA
  • "Presentation." 2009, Presented at DHLRI,
  • "Human Nutrition." 2009, Presented at OSU,
  • "Seminar." 2009, Presented at IBGP 797.01, Columbus, US|USA
  • "Scientific Sessions." 2009, Presented at AHA,
  • "Essential Role of Micro RNA in Wound Healing." 2009, Presented at SAWC/WHS, Dallas, US|USA
  • "Podium presentation." 2009, Presented at SAWC/WHS, Dallas, US|USA
  • "Impact on Health, Wellness, Environment and Economics." 2015, Presented at Translational Science and Drug Discovery, Balaclava, MU|MUS


  • Dr. Roy. "Lipoic acid analogues." Patent number: B98-46