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Aleksander Skardal

  • Assistant Professor, Biomedical Engineering
  • 1080 Carmack Rd
    Columbus, OH 43210

About

Education

  • B.S., Johns Hopkings University, 2005
  • Ph.D., University of Utah, 2010

Key Honors and Distinctions

  • Edison Awards “Game Changer Award” for Bioprinters in Regenerative Medicine (2013)
  • Clinical and Translational Science Institute Academy Scholar (2016)
  • Wake Forest Baptist Medical Center Research Excellence Award (2015, 2017, 2018) 

 RESEARCH AREAS – Skardal Lab for Tissue and Tumor Biofabrication

  • Bioengineering; Biofabrication; Bioprinting; Biomaterials; Tissue Engineering; Cancer; Organ-on-a-Chip; Cancer-on-a-Chip
  • Graduate student and postdoc research opportunities are currently available.

 PUBLICATIONS

https://scholar.google.com/citations?user=A68i3BUAAAAJ&hl=en&oi=ao

 PATENTS

https://patents.google.com/?inventor=skardal+aleksander&oq=skardal+aleksander

 

Our research program focuses on the design and implementation of extracellular matrix-inspired hydrogel biomaterials for the biofabrication of tissue and tumor organoids, organ-on-a-chip systems, and cancer-on-a-chip systems for drug screening, disease modeling, and personalized medicine. Our team’s work has broad applicability across tissue types and diseases but has focused primarily in development of cancer models and recently neural models. Our biomaterial systems are largely hyaluronic acid-based with additional custom ECM component addons, synthetically modified in the lab. These are often combined with microfluidic devices for fluid handling capabilities. In particular, we have a significant interest in patient biospecimen-derived models that can facilitate and improve current precision medicine and precision oncology efforts in the clinic.

Journal Articles

2020

  • Bedell, M.L.; Melchiorri, A.J.; Aleman, J.; Skardal, A. et al., 2020, "A high-throughput approach to compare the biocompatibility of candidate bioink formulations." Bioprinting 17,
  • Votanopoulos, K.I.; Forsythe, S.; Sivakumar, H.; Mazzocchi, A. et al., 2020, "Model of Patient-Specific Immune-Enhanced Organoids for Immunotherapy Screening: Feasibility Study.." Ann Surg Oncol 27, no. 6, 1956-1967 - 1956-1967.
  • Murphy, S.V.; Skardal, A.; Nelson, R.A.; Sunnon, K. et al., 2020, "Amnion membrane hydrogel and amnion membrane powder accelerate wound healing in a full thickness porcine skin wound model.." Stem Cells Transl Med 9, no. 1, 80-92 - 80-92.
  • Forsythe, S.; Mehta, N.; Devarasetty, M.; Sivakumar, H. et al., 2020, "Development of a Colorectal Cancer 3D Micro-tumor Construct Platform From Cell Lines and Patient Tumor Biospecimens for Standard-of-Care and Experimental Drug Screening.." Ann Biomed Eng 48, no. 3, 940-952 - 940-952.

2019

  • Forsythe, S.; Pu, T.; Skardal, A., 2019, "Using organoid models to predict chemotherapy efficacy: the future of precision oncology?." Expert Review of Precision Medicine and Drug Development 4, no. 6, 317-336 - 317-336.
  • Clark, C.C.; Aleman, J.; Mutkus, L.; Skardal, A., 2019, "A mechanically robust thixotropic collagen and hyaluronic acid bioink supplemented with gelatin nanoparticles." Bioprinting 16,
  • Mazzocchi, A.; Soker, S.; Skardal, A., 2019, "3D bioprinting for high-throughput screening: Drug screening, disease modeling, and precision medicine applications." Applied Physics Reviews 6, no. 1,
  • Albanna, M.; Binder, K.W.; Murphy, S.V.; Kim, J. et al., 2019, "In Situ Bioprinting of Autologous Skin Cells Accelerates Wound Healing of Extensive Excisional Full-Thickness Wounds.." Sci Rep 9, no. 1, 1856 - 1856.
  • Mazzocchi, A.; Devarasetty, M.; Herberg, S.; Petty, W.J. et al., 2019, "Pleural Effusion Aspirate for use in 3D Lung Cancer Modeling and Chemotherapy Screening.." ACS Biomater Sci Eng 5, no. 4, 1937-1943 - 1937-1943.
  • Aleman, J.; George, S.K.; Herberg, S.; Devarasetty, M. et al., 2019, "Deconstructed Microfluidic Bone Marrow On-A-Chip to Study Normal and Malignant Hemopoietic Cell-Niche Interactions.." Small 15, no. 43, e1902971 - e1902971.
  • Aleman, J.; Skardal, A., 2019, "A multi-site metastasis-on-a-chip microphysiological system for assessing metastatic preference of cancer cells.." Biotechnol Bioeng 116, no. 4, 936-944 - 936-944.
  • Votanopoulos, K.I.; Mazzocchi, A.; Sivakumar, H.; Forsythe, S. et al., 2019, "Appendiceal Cancer Patient-Specific Tumor Organoid Model for Predicting Chemotherapy Efficacy Prior to Initiation of Treatment: A Feasibility Study.." Ann Surg Oncol 26, no. 1, 139-147 - 139-147.
  • Serban, M.A.; Skardal, A., 2019, "Hyaluronan chemistries for three-dimensional matrix applications.." Matrix Biol 78-79, 337-345 - 337-345.

2018

  • Mazzocchi, A.; Votanopoulos, K.; Skardal, A., 2018, "Personalizing Cancer Treatments Empirically in the Laboratory: Patient-Specific Tumor Organoids for Optimizing Precision Medicine." Current Stem Cell Reports 4, no. 2, 97-104 - 97-104.
  • Devarasetty, M.; Mazzocchi, A.R.; Skardal, A., 2018, "Applications of Bioengineered 3D Tissue and Tumor Organoids in Drug Development and Precision Medicine: Current and Future.." BioDrugs 32, no. 1, 53-68 - 53-68.
  • Mazzocchi, A.R.; Rajan, S.A.P.; Votanopoulos, K.I.; Hall, A.R. et al., 2018, "In vitro patient-derived 3D mesothelioma tumor organoids facilitate patient-centric therapeutic screening.." Sci Rep 8, no. 1, 2886 - 2886.
  • Rivas, F.; Zahid, O.K.; Reesink, H.L.; Peal, B.T. et al., 2018, "Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor.." Nat Commun 9, no. 1, 1037 - 1037.
  • Forsythe, S.D.; Devarasetty, M.; Shupe, T.; Bishop, C. et al., 2018, "Environmental Toxin Screening Using Human-Derived 3D Bioengineered Liver and Cardiac Organoids.." Front Public Health 6, 103 - 103.
  • Votanopoulos, K.I.; Shen, P.; Skardal, A.; Levine, E.A., 2018, "Peritoneal Metastases from Appendiceal Cancer.." Surg Oncol Clin N Am 27, no. 3, 551-561 - 551-561.
  • Mazzocchi, A.; Devarasetty, M.; Huntwork, R.; Soker, S. et al., 2018, "Optimization of collagen type I-hyaluronan hybrid bioink for 3D bioprinted liver microenvironments.." Biofabrication 11, no. 1, 015003 - 015003.
  • Skardal, A., 2018, "Perspective: “Universal” bioink technology for advancing extrusion bioprinting-based biomanufacturing." Bioprinting 10,

2017

  • Skardal, A.; Murphy, S.; Atala, A.; Soker, S., 2017, "Bioprinting for Wound Healing Applications." Frontiers in Nanobiomedical Research 8, 325-353 - 325-353.
  • Zhang, Y.S.; Aleman, J.; Shin, S.R.; Kilic, T. et al., 2017, "Multisensor-integrated organs-on-chips platform for automated and continual in situ monitoring of organoid behaviors.." Proc Natl Acad Sci U S A 114, no. 12, E2293-E2302 - E2293-E2302.
  • Skardal, A.; Murphy, S.V.; Crowell, K.; Mack, D. et al., 2017, "A tunable hydrogel system for long-term release of cell-secreted cytokines and bioprinted in situ wound cell delivery.." J Biomed Mater Res B Appl Biomater 105, no. 7, 1986-2000 - 1986-2000.
  • Yi, H.; Forsythe, S.; He, Y.; Liu, Q. et al., 2017, "Tissue-specific extracellular matrix promotes myogenic differentiation of human muscle progenitor cells on gelatin and heparin conjugated alginate hydrogels.." Acta Biomater 62, 222-233 - 222-233.
  • Devarasetty, M.; Forsythe, S.; Shupe, T.D.; Soker, S. et al., 2017, "Optical Tracking and Digital Quantification of Beating Behavior in Bioengineered Human Cardiac Organoids.." Biosensors (Basel) 7, no. 3,
  • Devarasetty, M.; Wang, E.; Soker, S.; Skardal, A., 2017, "Mesenchymal stem cells support growth and organization of host-liver colorectal-tumor organoids and possibly resistance to chemotherapy.." Biofabrication 9, no. 2, 021002 - 021002.
  • Sivakumar, H.; Strowd, R.; Skardal, A., 2017, "Exploration of Dynamic Elastic Modulus Changes on Glioblastoma Cell Populations with Aberrant EGFR Expression as a Potential Therapeutic Intervention Using a Tunable Hyaluronic Acid Hydrogel Platform.." Gels 3, no. 3,
  • Skardal, A.; Murphy, S.V.; Devarasetty, M.; Mead, I. et al., 2017, "Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform.." Sci Rep 7, no. 1, 8837 - 8837.
  • Devarasetty, M.; Skardal, A.; Cowdrick, K.; Marini, F. et al., 2017, "Bioengineered Submucosal Organoids for In Vitro Modeling of Colorectal Cancer.." Tissue Eng Part A 23, no. 19-20, 1026-1041 - 1026-1041.
  • Murphy, S.V.; Skardal, A.; Song, L.; Sutton, K. et al., 2017, "Solubilized Amnion Membrane Hyaluronic Acid Hydrogel Accelerates Full-Thickness Wound Healing.." Stem Cells Transl Med 6, no. 11, 2020-2032 - 2020-2032.

2016

  • Skardal, A.; Devarasetty, M.; Kang, H-W.; Seol, Y-J. et al., 2016, "Bioprinting Cellularized Constructs Using a Tissue-specific Hydrogel Bioink.." J Vis Exp no. 110, e53606 - e53606.
  • Skardal, A.; Devarasetty, M.; Forsythe, S.; Atala, A. et al., 2016, "A reductionist metastasis-on-a-chip platform for in vitro tumor progression modeling and drug screening.." Biotechnol Bioeng 113, no. 9, 2020-2032 - 2020-2032.
  • Skardal, A.; Shupe, T.; Atala, A., 2016, "Organoid-on-a-chip and body-on-a-chip systems for drug screening and disease modeling.." Drug Discov Today 21, no. 9, 1399-1411 - 1399-1411.

2015

  • Skardal, A.; Devarasetty, M.; Kang, H-W.; Mead, I. et al., 2015, "A hydrogel bioink toolkit for mimicking native tissue biochemical and mechanical properties in bioprinted tissue constructs.." Acta Biomater 25, 24-34 - 24-34.
  • Deegan, D.B.; Zimmerman, C.; Skardal, A.; Atala, A. et al., 2015, "Stiffness of hyaluronic acid gels containing liver extracellular matrix supports human hepatocyte function and alters cell morphology.." J Mech Behav Biomed Mater 55, 87-103 - 87-103.
  • Skardal, A.; Atala, A., 2015, "Biomaterials for integration with 3-D bioprinting.." Ann Biomed Eng 43, no. 3, 730-746 - 730-746.
  • Skardal, A.; Devarasetty, M.; Soker, S.; Hall, A.R., 2015, "In situ patterned micro 3D liver constructs for parallel toxicology testing in a fluidic device.." Biofabrication 7, no. 3, 031001 - 031001.
  • Skardal, A.; Devarasetty, M.; Rodman, C.; Atala, A. et al., 2015, "Liver-Tumor Hybrid Organoids for Modeling Tumor Growth and Drug Response In Vitro.." Ann Biomed Eng 43, no. 10, 2361-2373 - 2361-2373.

2014

  • Niu, G.; Choi, J-S.; Wang, Z.; Skardal, A. et al., 2014, "Heparin-modified gelatin scaffolds for human corneal endothelial cell transplantation.." Biomaterials 35, no. 13, 4005-4014 - 4005-4014.
  • Skardal, A., 2014, "Extracellular matrix-like hydrogels for applications in regenerative medicine." RSC Soft Matter 191-215 - 191-215.

2013

  • Markert, C.D.; Guo, X.; Skardal, A.; Wang, Z. et al., 2013, "Characterizing the micro-scale elastic modulus of hydrogels for use in regenerative medicine.." J Mech Behav Biomed Mater 27, 115-127 - 115-127.
  • Murphy, S.V.; Skardal, A.; Atala, A., 2013, "Evaluation of hydrogels for bio-printing applications.." J Biomed Mater Res A 101, no. 1, 272-284 - 272-284.
  • Skardal, A.; Mack, D.; Atala, A.; Soker, S., 2013, "Substrate elasticity controls cell proliferation, surface marker expression and motile phenotype in amniotic fluid-derived stem cells.." J Mech Behav Biomed Mater 17, 307-316 - 307-316.
  • Park, A.H.; Hoyt, D.; Britt, D.; Chase, S. et al., 2013, "Cross-linked hydrogel and polyester resorbable ventilation tubes in a Chinchilla model.." Laryngoscope 123, no. 4, 1043-1048 - 1043-1048.

2012

  • Skardal, A.; Smith, L.; Bharadwaj, S.; Atala, A. et al., 2012, "Tissue specific synthetic ECM hydrogels for 3-D in vitro maintenance of hepatocyte function.." Biomaterials 33, no. 18, 4565-4575 - 4565-4575.
  • Skardal, A.; Mack, D.; Kapetanovic, E.; Atala, A. et al., 2012, "Bioprinted amniotic fluid-derived stem cells accelerate healing of large skin wounds.." Stem Cells Transl Med 1, no. 11, 792-802 - 792-802.

2011

  • Oottamasathien, S.; Jia, W.; McCoard, L.; Slack, S. et al., 2011, "A murine model of inflammatory bladder disease: cathelicidin peptide induced bladder inflammation and treatment with sulfated polysaccharides.." J Urol 186, no. 4 Suppl, 1684-1692 - 1684-1692.

2010

  • Skardal, A.; Sarker, S.F.; Crabbé, A.; Nickerson, C.A. et al., 2010, "The generation of 3-D tissue models based on hyaluronan hydrogel-coated microcarriers within a rotating wall vessel bioreactor.." Biomaterials 31, no. 32, 8426-8435 - 8426-8435.
  • Skardal, A.; Zhang, J.; Prestwich, G.D., 2010, "Bioprinting vessel-like constructs using hyaluronan hydrogels crosslinked with tetrahedral polyethylene glycol tetracrylates.." Biomaterials 31, no. 24, 6173-6181 - 6173-6181.
  • Skardal, A.; Zhang, J.; McCoard, L.; Xu, X. et al., 2010, "Photocrosslinkable hyaluronan-gelatin hydrogels for two-step bioprinting.." Tissue Eng Part A 16, no. 8, 2675-2685 - 2675-2685.
  • Skardal, A.; Zhang, J.; McCoard, L.; Oottamasathien, S. et al., 2010, "Dynamically crosslinked gold nanoparticle - hyaluronan hydrogels.." Adv Mater 22, no. 42, 4736-4740 - 4736-4740.

2008

  • Liu, Y.; Skardal, A.; Shu, X.Z.; Prestwich, G.D., 2008, "Prevention of peritendinous adhesions using a hyaluronan-derived hydrogel film following partial-thickness flexor tendon injury.." J Orthop Res 26, no. 4, 562-569 - 562-569.
  • Zhang, J.; Skardal, A.; Prestwich, G.D., 2008, "Engineered extracellular matrices with cleavable crosslinkers for cell expansion and easy cell recovery.." Biomaterials 29, no. 34, 4521-4531 - 4521-4531.

Papers in Proceedings

2019

  • Devarasetty, M.; Herberg, S.; Dominijanni, A.; Willey-Shelkey, E. et al. "Biofabricated tumor microenvironments for studying colorectal cancer in vitro and in vivo." in Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO). (5 2019).
  • Rodriguez, C.; Aleman, J.; Almeida-Porada, G.; Porada, C. et al. "High throughput 3D bioprinting of patient-derived multiple myeloma organoid models for niche recapitulation and chemosensitivity assessment.." (10 2019).
  • Rodriguez, C.; Aleman, J.; George, S.; Maycock, A. et al. "Patient-Specific 3D Printed Multiple Myeloma Organoid Model for Niche Recapitulation and Prediction of Chemotherapy Response." (9 2019).
  • Votanopoulos, K.I.; Sivakjumar, H.; Forsythe, S.; Mazzocchi, A. et al. "Model of Patient-Specific Mixed Melanoma/Lymph Node Organoid for Predicting Immunotherapy Response: Feasibility Study." in 72nd Annual Cancer Symposium of the Society-of-Surgical-Oncology (SSO). (2 2019).

2018

  • Shi, L.; Foster, B.; Harris, K.; Skardal, A. et al. "CD117 tyrosine kinase activation drives prostate cancer aggressiveness." in AACR Special Conference on Prostate Cancer - Advances in Basic, Translational, and Clinical Research. (8 2018).
  • Shi, L.; Harris, K.; Foster, B.; Skardal, A. et al. "CD117 tyrosine kinase activation drives prostate cancer aggressiveness." in Annual Meeting of the American-Association-for-Cancer-Research (AACR). (7 2018).

2017

  • Mazzocchi, A.; Soker, S.; Skardal, A. "Hyaluronan-Collagen Type-I Hybrid Bioink for 3D Printed Microenvironments." in TERMIS - Americas Conference and Exhibition. (12 2017).
  • Forsythe, S.; Mehta, N.; Devarasetty, M.; Mazzochi, A. et al. "A Tumor-on-a-Chip Platform for Screening Precision Driven Medicines." in TERMIS - Americas Conference and Exhibition. (12 2017).
  • Devarasetty, M.; Forsythe, S.; Murphy, S.; Shupe, T. et al. "Multi-tissue Interactions In An Integrated Three-tissue Organ-on-a-chip Platform." in TERMIS - Americas Conference and Exhibition. (12 2017).
  • Devarasetty, M.; Skardal, A.; Soker, S. "Rheology vs Alignment: Two Operators of the Mechanical Tumor Microenvironment." in TERMIS - Americas Conference and Exhibition. (12 2017).
  • Sivakumar, H.; Skardal, A. "An In Vitro Model of Glioblastoma." in TERMIS - Americas Conference and Exhibition. (12 2017).
  • Forsythe, S.; Devarasetty, M.; Shupe, T.; Bishop, C. et al. "Drug and Environmental Toxin Screening in Bioengineered Liver and Cardiac Tissue Analogs." in TERMIS - Americas Conference and Exhibition. (12 2017).
  • Mazzocchi, A.; Votanopoulos, K.; Soker, S.; Skardal, A. "Primary Patient Tumor Organoids for Personalized Drug Treatment." in TERMIS - Americas Conference and Exhibition. (12 2017).
  • Aleman, J.; George, S.K.; Porada, C.D.; Almeida-Porada, G. et al. "Exploring Normal and Malignant Hematopoietic Stem/Progenitos Cell-Niche Interactions Using a Novel Bone Marrow-on-a-Chip Platform." in TERMIS - Americas Conference and Exhibition. (12 2017).
  • Gmeiner, W.H.; Dominijanni, A.; Boyacioglu, O.; Forsyth, S. et al. "The polymeric fluoropyrimidine F10 is effective towards cell and organoid models of 5-FU-resistant colorectal cancer." in Annual Meeting of the American-Association-for-Cancer-Research (AACR). (7 2017).
  • George, S.; Aleman, J.; Almeida-Porada, M.G.; Skardal, A. et al. "Recreating the Hematopoietic Microenvironment in Vitro Using Microfluidic "on-a-Chip" Technology Enables the Study of Interactions of Normal and Malignant HSPC with Specific Bone Marrow Niches." in 59th Annual Meeting of the American-Society-of-Hematology (ASH). (12 2017).
  • Harris, K.; Shi, L.; Peak, T.; Sanders, S. et al. "CD117 expression and activation induce prostate cancer metastasis." in Annual Meeting of the American-Association-for-Cancer-Research (AACR). (7 2017).
  • Yoo, K.; Huntwork, C.; Banks, S.; Skardal, A. et al. "Enhancing Tissue Adhesives with Small Molecule Additives." in TERMIS - Americas Conference and Exhibition. (12 2017).
  • Rajan, S.; Aleman, J.; Wan, M.; Zarandi, N.P. et al. "Adhesive Film Based Multi-organoid Body-on-a-chip Platform For Assessing Drug Efficiency And Toxicity." in TERMIS - Americas Conference and Exhibition. (12 2017).
  • Rajan, S.; Mazzocchi, A.R.; Skardal, A.; Hall, A.R. "Tumor-on-a-chip Microfluidic Devices for Personalized Cancer Drug Testing." in TERMIS - Americas Conference and Exhibition. (12 2017).
  • Rajan, S.; Hambright, P.; Skardal, A.; Hall, A.R. "Adhesive Film-based Microfluidic Device For Motility Assessment Of Cancer Cells." in TERMIS - Americas Conference and Exhibition. (12 2017).
  • Mazzocchi, A.; Rajan, S.; Votanopoulos, K.; Hall, A. et al. "Primary Patient Mesothelioma Organoids for Genetic Mutation-Driven Experimental 3-Deazaneplanocin a Treatment." in TERMIS - Americas Conference and Exhibition. (12 2017).

2016

  • Aleman, J.; Skardal, A. "Multiple Organ-on-a-Chip Platform for Metastasis Dynamic Studies." in TERMIS - Americas Conference and Exhibition. (12 2016).
  • Devarasetty, M.; Forsythe, S.; Murphy, S.; Shupe, T. et al. "A Bioengineered Multi-Organoid Body-on-a-Chip Platform for Advanced Drug Screening." in TERMIS - Americas Conference and Exhibition. (12 2016).
  • Forsythe, S.; Mehta, N.; Alistar, A.; Hall, A. et al. "A Tumor-on-a-chip Platform For Screening Precision Medicine-driven Therapies." in TERMIS - Americas Conference and Exhibition. (12 2016).
  • Rajan, S.; Hambright, P.; Skardal, A.; Hall, A.R. "Microfluidic Device For Motility And Biochemical Assessment In Parallel Drug Testing." in TERMIS - Americas Conference and Exhibition. (12 2016).
  • Sivakumar, H.; Devarasetty, M.; Skardal, A. "An In Vitro Model of Glioblastoma and the Brain Tumor Microenvironment." in TERMIS - Americas Conference and Exhibition. (12 2016).
  • Devarasetty, M.; Skardal, A.; Soker, S. "A 3D Submucosal Microenvironment for Investigation of Topography Induced Effects in Colorectal Cancer Cells." in TERMIS - Americas Conference and Exhibition. (12 2016).
  • Aleman, J.; Zhang, Y.; Skardal, A.; Khademhosseini, A. "Lego-inspired Organ-on-a-chip Gelatin Methacryloyl Microfluidic System." in TERMIS - Americas Conference and Exhibition. (12 2016).

2015

  • Yi, H.; Forsythe, S.; Zhang, Y.; Skardal, A. "Bio-Functionalized Alginate Hydrogels for Improved Cell-matrix Interactions and Growth Factor Sequestration Kinetics." in 4th TERMIS World Congress. (9 2015).
  • Seol, Y.; Kang, H.; Lee, S.; Jackson, J.D. et al. "3-D Bioprinting of Tissue Organoids for Body-on-a-Chip Drug Screening Platform." in 4th TERMIS World Congress. (9 2015).
  • Skardal, A.; Devarasetty, M.; Kang, H.; Mead, I. et al. "A Hydrogel Bioink Toolkit for Bioprinting Tissue Constructs while Mimicking Native Tissue Biochemical and Mechanical Properties." in 4th TERMIS World Congress. (9 2015).
  • Skardal, A.; Kleensang, A.; Devarasetty, M.; Kang, H. et al. "Physiologically Relevant Drug Testing In Vitro - An Integrated Multiple Organoid-on-a-Chip Approach." in 4th TERMIS World Congress. (9 2015).
  • Devarasetty, M.; Forsythe, S.; Soker, S.; Hall, A. et al. "Ultra-thin Tissue-Tumor Organoid Microfluidic Platforms For In Vitro Diagnostics." in 4th TERMIS World Congress. (9 2015).
  • Devarasetty, M.; Skardal, A.; Soker, S. "A 3D Stratified Colon Model for Colorectal Cancer Progression." in 4th TERMIS World Congress. (9 2015).
  • Murphy, S.; Skardal, A.; Sutton, K.; Reid, T. et al. "Amnion Membrane Hydrogel Accelerates Skin Wound Healing." in 4th TERMIS World Congress. (9 2015).

2014

  • Skardal, A.; Devarasetty, M.; Rodman, C.; Atala, A. et al. "An In Vitro 3-D Liver-Tumor Hybrid Organoid System for Modeling Metastasis and Drug Resistance." in TERMIS-AM Conference. (12 2014).
  • Devarasetty, M.; Atala, A.; Soker, S.; Skardal, A. "A Metastasis-on-a-Chip System for Modeling Colon Carcinoma Migration and Invasion In Vitro." in TERMIS-AM Conference. (12 2014).
  • Murphy, S.V.; Skardal, A.; Sutton, K.; Reid, T. et al. "Amnion Hydrogel Accelerates Skin Wound Healing." in TERMIS-AM Conference. (12 2014).
  • Skardal, A.; Mead, I.; Devarasetty, M.; Kang, H. et al. "Integration of 3-D Organoid Bioprinting and Microfluidic Device Technology for Functional Primary Cell-Based Liver-on-a-Chip Operation." in TERMIS-AM Conference. (12 2014).
  • Skardal, A.; Devarasetty, M.; Atala, A.; Soker, S. et al. "A Microfluidic Platform for Parallel Analysis of In Situ Patterned 3-D Liver Organoids." in TERMIS-AM Conference. (12 2014).
  • Devarasetty, M.; Skardal, A.; Soker, S. "Modeling the Colon-Tumor Microenvironment Using Multicellular Hydrogel Strata." in TERMIS-AM Conference. (12 2014).

2013

  • Markert, C.D.; Guo, X.; Skardal, A.; Bharadwaj, S. et al. "How Stiff Is It? Characterizing the micro-scale elastic modulus of hydrogels for use in regenerative medicine." in Joint Annual Meeting of the ASPET/BPS at Experimental Biology (EB). (4 2013).

2012

  • Skardal, A.; Mack, D.; Kapetanovic, E.; Markert, C. et al. "Bioprinted amniotic fluid-derived stem cells accelerate wound healing in skin." (9 2012).
  • Skardal, A.; Smith, L.; Shantaram, B.; Soker, S. et al. "Tissue-specific synthetic ECM hydrogels for 3-D in vitro maintenance of hepatocyte function." (9 2012).
  • Mack, D.L.; Skardal, A.; Yoo, J.; Soker, S. "Bioprinted Amniotic Fluid-Derived Stem Cells Accelerate Wound Healing in Skin." in 15th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT). (5 2012).