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Noah Weisleder

  • Director, Postdoc Affairs Offi, OR Office of Postdoc Affairs
  • Associate Professor, SBS-Biolog Chem & Pharmacology
  • Associate Professor, SBS-Physiology & Cell Biology
  • 473 W 12th Ave Room 605
    Columbus, OH 43210
  • 614-292-5321

Honors

  • 20141001

    Chair of Cell and Gene Therapy Session.

  • 20140501

    Chair of Featured Topic at Experimental Biology 2015.

  • 20130401

    Annual Meeting Abstract Chair for Muscle Biology.

  • 20130101

    Paper of the Week.

  • 20110701

    World Congress: Best Poster Award.

  • 20110301

    Kauffman Foundation Outstanding Postdoctoral Entrepreneur Award.

  • 20110201

    Featured Alumni.

  • 20100501

    Finalist for New Innovator Award.

  • 20090101

    Paper of the Week – Jan. 2009.

  • 20070201

    Chair of Skeletal E-C Coupling Platform Session.

  • 20060601-20060801

    Visiting Scholar Position.

  • 20060201

    Chair of Local Ca2+ Signaling Platform Session.

  • 20050601

    Best Postdoctoral Research Award.

  • 20020601

    Research Award: Outstanding Poster.

Journal Articles

2014

  • Manring,Heather; Abreu,Eduardo; Brotto,Leticia; Weisleder,Noah; Brotto,Marco, 2014, "Novel excitation-contraction coupling related genes reveal aspects of muscle weakness beyond atrophy—new hopes for treatment of musculoskeletal diseases." Frontiers in Physiology 5, no. 37, fphys.2014.00037 - fphys.2014.00037.
  • Jia,Yanlin; Chen,Ken; Lin,Pei-Hui; Lieber,Gissela; Nishi,Miyuki; Yan,Rosalie; Wang,Zhen; Yao,Yonggang; Li,Yu; Whitson,Bryan; Duann,Pu; Li,Haichang; Zhou,Xinyu; Zhu,Hua; Takeshima,Hiroshi; Hunter,John C; McLeod,Robbie L; Weisleder,Noah; Zeng,Chunyu; Ma,Jianjie, 2014, "Treatment of acute lung injury by targeting ​MG53-mediated cell membrane repair.." Nature Communications 5, 4387 - 4387.
  • Agarwal,S; Blazek,A; Young,N; Wu,L-C; Lebelebicioglu,B; Hewett,T; JARJOUR,W; Weisleder,N, 2014, "PHYSICAL EXERCISE ATTENUATES INFLAMMATION VIA SUPPRESSION OF SYSTEMIC MACROPHAGE ACTIVATION." OSTEOARTHRITIS AND CARTILAGE 22, S309-S309 - S309-S309.
  • Xu,Zhaobin; Alloush,Jenna; Beck,Eric; Weisleder,Noah, 2014, "A murine model of myocardial ischemia-reperfusion injury through ligation of the left anterior descending artery.." Journal of visualized experiments : JoVE 2014, no. 86, Online - Online.
  • Blazek,A,D; Perera,P; Wu,L-C; Litsky,A; Sun,Z; Kim,D-G; Lebelebicioglu,B; Lee,B; Hewett,T,E; Weisleder,N,L; Agarwal,S, 2014, "SKELETAL EFFECTS OF MECHANICAL LOAD ARE SYSTEMIC AND MAINTAINED THROUGH FSTL3." OSTEOARTHRITIS AND CARTILAGE 22, S126-S127 - S126-S127.
  • Xu,Zhaobin; Alloush,Jenna; Beck, Eric; Weisleder,Noah, 2014, "A Murine Model of Myocardial Ischemia-reperfusion Injury through Ligation of the Left Anterior Descending Artery.." Journal of visualized experiments : JoVE 10, no. 86, e51329 - e51329.
  • Park,Ki,Ho; Weisleder,Noah; Zhou,Jingsong; Gumpper,Kristyn; Zhou,Xinyu; Duann,Pu; Ma,Jianjie; Lin,Pei-Hui, 2014, "Assessment of calcium sparks in intact skeletal muscle fibers.." Journal of visualized experiments : JoVE E, no. 84, e50898 - e50898.
  • Agarwal,S; Blazek,A; Young,N; Wu,L-C; Lebelebicioglu,B; Hewett,T; JARJOUR,W; Weisleder,N, 2014, "PHYSICAL EXERCISE ATTENUATES INFLAMMATION VIA SUPPRESSION OF SYSTEMIC MACROPHAGE ACTIVATION." OSTEOARTHRITIS AND CARTILAGE 22, S309-S309 - S309-S309.
  • Zhao,Shuting; Agarwal,Pranay; Rao,Wei; Huang,Haishui; Zhang,Renliang, Liu,Zhenguo; Yu,Jianhua; Weisleder,Noah; Zhangi,Wujie; He,Xiaoming, 2014, "Coaxial electrospray of liquid core–hydrogel shell microcapsules for encapsulation and miniaturized 3D culture of pluripotent stem cells." Integrative Biology Online, DOI:10.1039/C4IB00100 - DOI:10.1039/C4IB00100.

2013

  • Leon-Salas,Walter,D; Rizk,Hatem; Mo,ChengLin; Weisleder,Noah; Brotto,Leticia; Abreu,Eduardo; Brotto,Marco, 2013, "A dual mode pulsed electro-magnetic cell stimulator produces acceleration of myogenic differentiation.." Recent patents on biotechnology 7, no. 1, 71-81 - 71-81.
  • Ferrante,Christopher; Szappanos,Henrietta; Csernoch,Laszlo; Weisleder,Noah, 2013, "Analysis of osmotic stress induced Ca2+ spark termination in mammalian skeletal muscle." INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS 50, no. 5, 411-418 - 411-418.
  • Orange,Mattew; Ferrante,Christopher; Yan,Rosalie; Tan,Tao; Takizawa,Norio; Lin,Pei-Hui; Li,Haichang; Takeshima,Hiroshi; Weisleder,Noah; Ma,Jianjie, 2013, "MG53 can Function in Keratinocyte Membrane Repair and Contribute to Excisional Wound Healing in Rodent Skin." BIOPHYSICAL JOURNAL 104, no. 2, 293A-293A - 293A-293A.
  • Alloush,Jenna; Weisleder,Noah, 2013, "TRIM Proteins in Therapeutic Membrane Repair of Muscular Dystrophy." JAMA NEUROLOGY 70, no. 7, 928-931. (7.58) - 928-931. (7.58).
  • Karam,Chehade,N; Yi,Jianxun; Manno,Carlo; Deng,Han-Xiang; Xu,Jiajie; Li,Kaitao; Weisleder,Noah; Ma,Jianjie; Cheng,Heping; Zhou,Jingsong, 2013, "Increased Mitochondrial Superoxide Production in the Skeletal Muscle Derived from a Double-Transgenic Mouse Model of Amyotrophic Lateral Sclerosis." BIOPHYSICAL JOURNAL 104, no. 2, 659A-659A - 659A-659A.

2012

  • Tjondrokoesoemo,Andoria; Li,Na; Pan,Zui; Ferrante,Christopher,J; Weisleder,Noah; Ma,Jianjie, 2012, "Inositol 1,4,5 Trisphosphate Receptor Type 1 (IP(3)R1) Activate Ryanodine Receptor (RyR1) to Mediate Ca2+ Spark Signaling in Adult Mammalian Skeletal Muscle." BIOPHYSICAL JOURNAL 102, no. 3, 226A-226A - 226A-226A.
  • Zhu,Hua; Lin,Pei-Hui; De,Gejing; Choi,Kyoung-Han; Takeshima,Hiroshi; Weisleder,Noah; Ma,Jianjie, 2012, "PTRF Anchors MG53 to Cell Injury Site for Initiation of Membrane Repair." BIOPHYSICAL JOURNAL 102, no. 3, 366A-366A - 366A-366A.
  • Moloughney,Joseph,G; Weisleder,Noah, 2012, "Poloxamer 188 (p188) as a membrane resealing reagent in biomedical applications.." Recent patents on biotechnology 6, no. 3, 200-211 - 200-211.
  • Lin,Peihui; Zhu,Hua; Cai,Chuanxi; Wang,Xianhua; Cao,Chunmei; Xiao,Ruiping; Pan,Zui; Weisleder,Noah; Takeshima,Hiroshi; Ma,Jianjie, 2012, "Nonmuscle myosin IIA facilitates vesicle trafficking for MG53-mediated cell membrane repair." FASEB JOURNAL 26, no. 5, 1875-1883 - 1875-1883.
  • Zhao,Xiaoli; Moloughney,Joseph,G; Zhang,Sai; Komazaki,Shinji; Weisleder,Noah, 2012, "Orai1 Mediates Exacerbated Ca2+ Entry in Dystrophic Skeletal Muscle." PLOS ONE 7, no. 11, e49862 - e49862.
  • Orange,Matthew; Lin,Peihui; Zhu,Hua; Weisleder,Noah; Ma,Jianjie, 2012, "Additive Phenotype of MG53 and Dysferlin Deficiencies in Membrane Repair Function of Skeletal Muscle Fibers." BIOPHYSICAL JOURNAL 102, no. 3, 154A-154A - 154A-154A.
  • Weisleder,Noah; Zhou,Jingsong; Ma,Jianjie, 2012, "Detection of calcium sparks in intact and permeabilized skeletal muscle fibers.." Methods in molecular biology (Clifton, N.J.) 798, 395-410 - 395-410.
  • Weisleder,Noah; Zhou,Jingsong; Ma,Jianjie, 2012, "Detection of calcium sparks in intact and permeabilized skeletal muscle fibers.." Methods in molecular biology (Clifton, N.J.) 798, 395-410 - 395-410.
  • Weisleder,Noah; Takizawa,Norio; Tan,Tao; Ferrante,Christopher; Chen,Pin-Jung; Yan,Rosalie; Zhao,Xiaoli; Cai,Chuanxi; Takeshima,Hiroshi; Ma,Jianjie, 2012, "Recombinant MG53 Protein can Increase Membrane Repair Capacity and Improve Pathology in Dystrophic Mouse Muscle." BIOPHYSICAL JOURNAL 102, no. 3, 720A-720A - 720A-720A.
  • Weisleder,Noah; Takizawa,Norio; Lin,Peihui; Wang,Xianhua; Cao,Chunmei; Zhang,Yan; Tan,Tao; Ferrante,Christopher; Zhu,Hua; Chen,Pin-Jung; Yan,Rosalie; Sterling,Matthew; Zhao,Xiaoli; Hwang,Moonsun; Takeshima,Miyuki; Cai,Chuanxi; Cheng,Heping; Takeshima,Hiroshi; Xiao,Rui-Ping; Ma,Jianjie, 2012, "Recombinant MG53 Protein Modulates Therapeutic Cell Membrane Repair in Treatment of Muscular Dystrophy." SCIENCE TRANSLATIONAL MEDICINE 4, no. 139, 139ra85 - 139ra85.
  • He,Bo; Tang,Ru-Hang; Weisleder,Noah; Xiao,Bin; Yuan,Zhenhua; Cai,Chuanxi; Zhu,Hua; Lin,Peihui; Qiao,Chunping; Li,Jianbin; Mayer,Christina; Li,Juan; Ma,Jianjie; Xiao,Xiao, 2012, "Enhancing Muscle Membrane Repair by Gene Delivery of MG53 Ameliorates Muscular Dystrophy and Heart Failure in delta-Sarcoglycan-deficient Hamsters." MOLECULAR THERAPY 20, no. 4, 727-735 - 727-735.

2011

  • Hwang,Moonsun; Ko,Jae-Kyun; Weisleder,Noah; Takeshima,Hiroshi; Ma,Jianjie, 2011, "Redox-dependent oligomerization through a leucine zipper motif is essential for MG53-mediated cell membrane repair." AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 301, no. 1, C106-C114 - C106-C114.
  • Yi,Jianxun; Ma,Changling; Li,Yan; Weisleder,Noah; Rios,Eduardo; Ma,Jianjie; Zhou,Jingsong, 2011, "Mitochondrial Calcium Uptake Regulates Rapid Calcium Transients in Skeletal Muscle during Excitation-Contraction (E-C) Coupling." JOURNAL OF BIOLOGICAL CHEMISTRY 286, no. 37, 32436-32443 - 32436-32443.
  • Weisleder,Noah; Lin,Peihui; Zhao,Xiaoli; Orange,Matthew; Zhu,Hua; Ma,Jianjie, 2011, "Visualization of MG53-mediated cell membrane repair using in vivo and in vitro systems.." Journal of visualized experiments : JoVE E, no. 52, 2717 - 2717.
  • Landstrom,Andrew,P; Kellen,Cherisse,A; Dixit,Sayali,S; van Oort,Ralph,J; Garbino,Alejandro; Weisleder,Noah; Ma,Jianjie; Wehrens,Xander,HT; Ackerman,Michael,J, 2011, "Junctophilin-2 Expression Silencing Causes Cardiocyte Hypertrophy and Abnormal Intracellular Calcium-Handling." CIRCULATION-HEART FAILURE 4, no. 2, 214-223 - 214-223.
  • Ko,Jae-Kyun; Choi,Kyoung-Han; Peng,Jun; He,Feng; Zhang,Zhi; Weisleder,Noah; Lin,Jialing; Ma,Jianjie, 2011, "Amphipathic Tail-anchoring Peptide and Bcl-2 Homology Domain-3 (BH3) Peptides from Bcl-2 Family Proteins Induce Apoptosis through Different Mechanisms." JOURNAL OF BIOLOGICAL CHEMISTRY 286, no. 11, 9038-9048 - 9038-9048.
  • Waddell,Leigh,B; Lemckert,Frances,A; Zheng,Xi,F; Tran,Jenny; Evesson,Frances,J; Hawkes,Joanne,M; Lek,Angela; Street,Neil,E; Lin,Peihui; Clarke,Nigel,F; Landstrom,Andrew,P; Ackerman,Michael,J; Weisleder,Noah; Ma,Jianjie; North,Kathryn,N; Cooper,Sandra,T, 2011, "Dysferlin, Annexin A1, and Mitsugumin 53 Are Upregulated in Muscular Dystrophy and Localize to Longitudinal Tubules of the T-System With Stretch." JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 70, no. 4, 302-313 - 302-313.
  • Tjondrokoesoemo,Andoria; Park,Ki,Ho; Ferrante,Christopher; Komazaki,Shinji; Lesniak,Sebastian; Brotto,Marco; Ko,Jae-Kyun; Zhou,Jingsong; Weisleder,Noah; Ma,Jianjie, 2011, "Disrupted Membrane Structure and Intracellular Ca2+ Signaling in Adult Skeletal Muscle with Acute Knockdown of Bin1." PLOS ONE 6, no. 9, e25740 - e25740.
  • Zhu,Hua; Lin,Peihui; De,Gejing; Choi,Kyoung-Han; Takeshima,Hiroshi; Weisleder,Noah; Ma,Jianjie, 2011, "Polymerase Transcriptase Release Factor (PTRF) Anchors MG53 Protein to Cell Injury Site for Initiation of Membrane Repair." JOURNAL OF BIOLOGICAL CHEMISTRY 286, no. 15, 12820-12824 - 12820-12824.
  • Touchberry,Chad,D; Elmore,Chris,J; Nguyen,Tien,M; Andresen,Jon,J; Zhao,Xiaoli; Orange,Matthew; Weisleder,Noah; Brotto,Marco; Claycomb,William,C; Wacker,Michael,J, 2011, "Store-operated calcium entry is present in HL-1 cardiomyocytes and contributes to resting calcium." BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 416, no. 1-2, 45-50 - 45-50.

2010

  • Woo,Jin,Seok; Hwang,Ji-Hye; Ko,Jae-Kyun; Weisleder,Noah; Kim,Do,Han; Ma,Jianjie; Lee,Eun,Hui, 2010, "S165F mutation of junctophilin 2 affects Ca2+ signalling in skeletal muscle." BIOCHEMICAL JOURNAL 427, 125-134 - 125-134.
  • Ko,Jae-Kyun; Peng,Jun; Choi,Kyoung-Han; Zhang,Zhi; Zong,Wei-Xing; Weisleder,Noah; Lin,Jialing; Ma,Jianjie, 2010, "Amphipathic Tail-Anchoring Peptide and BH3 Peptide Induced Mitochondrial Permeabilization and Apoptosis are Mechanistically Distinct." BIOPHYSICAL JOURNAL 98, no. 3, 465A-465A - 465A-465A.
  • Zhao,Xiaoli; Min,Choon,Kee; Ko,Jae-Kyun; Parness,Jerome; Kim,Do,Han; Weisleder,Noah; Ma,Jianjie, 2010, "Increased Store-Operated Ca2+ Entry in Skeletal Muscle with Reduced Calsequestrin-1 Expression." BIOPHYSICAL JOURNAL 99, no. 5, 1556-1564 - 1556-1564.
  • Zhao,Xiaoli; Weisleder,Noah, 2010, "Orai1 Mediates Store-Operated Ca2+Entry in Normal Skeletal Muscle and Exacerbated Ca2+Entry in Dystrophic Muscle." BIOPHYSICAL JOURNAL 98, no. 3, 297A-297A - 297A-297A.
  • Park,Ki,Ho; Zhao,Xiaoli; Yamazaki,Daiju; Pitt,Samantha; Tjondrokoesoemo,Andoria; Komazaki,Shinji; Ko,Jae-Kyun; Lin,Pei-Hui; Brotto,Marco; Sitsapesan,Rebecca; Weisleder,Noah; Takeshima,Hiroshi; Ma,Jianjie, 2010, "Knockdown of TRIC-B from tric-a(-/-) mice Alters Intracellular Ca2+ Signaling in Skeletal and Cardiac Muscles." BIOPHYSICAL JOURNAL 98, no. 3, 548A-548A - 548A-548A.
  • Tjondrokoesoemo,Andoria; Weisleder,Noah; Ma,Jianjie, 2010, "Compromised Ca2+ Sparks Signaling in the Skeletal Muscle of Diabetic Type 2 Mice." BIOPHYSICAL JOURNAL 98, no. 3, 295A-295A - 295A-295A.
  • Cao,Chun-mei; Zhang,Yan; Weisleder,Noah; Ferrante,Christopher; Wang,Xianhua; Lv,Fengxiang; Zhang,Yi; Song,Ruisheng; Hwang,Moonsun; Jin,Li; Guo,Jiaojiao; Peng,Wei; Li,Geng; Nishi,Miyuki; Takeshima,Hiroshi; Ma,Jianjie; Xiao,Rui-Ping, 2010, "MG53 Constitutes a Primary Determinant of Cardiac Ischemic Preconditioning." CIRCULATION 121, no. 23, 2565-U74 - 2565-U74.
  • Belakavadi,Madesh; Saunders,Jason; Weisleder,Noah; Raghava,Preethi,S; Fondell,Joseph,D, 2010, "Repression of Cardiac Phospholamban Gene Expression Is Mediated by Thyroid Hormone Receptor-alpha 1 and Involves Targeted Covalent Histone Modifications." ENDOCRINOLOGY 151, no. 6, 2946-2956 - 2946-2956.
  • Wang,Xianhua; Xie,Wenjun; Zhang,Yi; Lin,Peihui; Han,Liang; Han,Peidong; Wang,Yanru; Chen,Zheng; Ji,Guangju; Zheng,Ming; Weisleder,Noah; Xiao,Rui-Ping; Takeshima,Hiroshi; Ma,Jianjie; Cheng,Heping, 2010, "Cardioprotection of Ischemia/Reperfusion Injury by Cholesterol-Dependent MG53-Mediated Membrane Repair." CIRCULATION RESEARCH 107, no. 1, 76-U155 - 76-U155.
  • Hwang,Moonsun; Ko,Jae-Kyun; Cai,Chuanxi; Lin,Peihui; Pan,Zui; Weisleder,Noah; Nishi,Miyuki; Takeshima,Hiroshi; Ma,Jianjie, 2010, "Leucine-Zipper Mediated Intermolecular Interaction between MG53 is Essential for Cellular Membrane Repair." BIOPHYSICAL JOURNAL 98, no. 3, 153A-153A - 153A-153A.

2009

  • Cai,Chuanxi; Masumiya,Haruko; Weisleder,Noah; Matsuda,Noriyuki; Nishi,Miyuki; Hwang,Moonsun; Ko,Jae-Kyun; Lin,Peihui; Thornton,Angela; Zhao,Xiaoli; Pan,Zui; Komazaki,Shinji; Brotto,Marco; Takeshima,Hiroshi; Ma,Jianjie, 2009, "MG53 nucleates assembly of cell membrane repair machinery." NATURE CELL BIOLOGY 11, no. 1, 56-U108 - 56-U108.
  • Li,Na; Lin,Peihui; Cai,Chuanxi; Pan,Zui; Weisleder,Noah; Ma,Jianjie, 2009, "The amino-terminal peptide of Bax perturbs intracellular Ca2+ homeostasis to enhance apoptosis in prostate cancer cells." AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 296, no. 2, C267-C272 - C267-C272.
  • Cai,Chuanxi; Weisleder,Noah; Ko,Jae-Kyun; Komazaki,Shinji; Sunada,Yoshihide; Nishi,Miyuki; Takeshima,Hiroshi; Ma,Jianjie, 2009, "Membrane Repair Defects in Muscular Dystrophy Are Linked to Altered Interaction between MG53, Caveolin-3, and Dysferlin." JOURNAL OF BIOLOGICAL CHEMISTRY 284, no. 23, 15894-15902 - 15894-15902.
  • Weisleder,Noah; Takeshima,Hiroshi; Ma,Jianjie, 2009, "Mitsugumin 53 (MG53) facilitates vesicle trafficking in striated muscle to contribute to cell membrane repair.." Communicative & integrative biology 2, no. 3, 225-226 - 225-226.

2008

  • Weisleder,Noah; Takeshima,Hiroshi; Ma,Jianjie, 2008, "Immuno-proteomic approach to excitation-contraction coupling in skeletal and cardiac muscle: Molecular insights revealed by the mitsugurnins." CELL CALCIUM 43, no. 1, 1-8 - 1-8.
  • Zhao,Xiaoli; Weisleder,Noah; Thornton,Angela; Oppong,Yaa; Campbell,Rachel; Ma,Jianjie; Brotto,Marco, 2008, "Compromised store-operated Ca2+ entry in aged skeletal muscle." AGING CELL 7, no. 4, 561-568 - 561-568.
  • Weisleder,Noah; Ma,Jianjie, 2008, "Altered Ca2+ sparks in aging skeletal and cardiac muscle." AGEING RESEARCH REVIEWS 7, no. 3, 177-188 - 177-188.
  • Zhu,Hua; Weisleder,Noah; Wu,Ping; Cai,Chuanxi; Chen,Jian-Wen, 2008, "Caveolae/Caveolin-1 are important modulators of store-operated calcium entry in Hs578/T breast cancer cells." JOURNAL OF PHARMACOLOGICAL SCIENCES 106, no. 2, 287-294 - 287-294.
  • Mavroidis,Manolis; Panagopoulou,Panagiota; Kostavasili,Ioanna; Weisleder,Noah; Capetanaki,Yassemi, 2008, "A missense mutation in desmin tail domain linked to human dilated cardiomyopathy promotes cleavage of the head domain and abolishes its Z-disc localization." FASEB JOURNAL 22, no. 9, 3318-3327 - 3318-3327.

2007

  • Weisleder,Noah; Ferrante,Christopher; Hirata,Yutaka; Collet,Claude; Chu,Yi; Cheng,Heping; Takeshima,Hiroshi; Ma,Jianjie, 2007, "Systemic ablation of RyR3 alters Ca2+ spark signaling in adult skeletal muscle." CELL CALCIUM 42, no. 6, 548-555 - 548-555.
  • Yazawa,Masayuki; Ferrante,Christopher; Feng,Jue; Mio,Kazuhiro; Ogura,Toshihiko; Zhang,Miao; Lin,Pei-Hui; Pan,Zui; Komazaki,Shinji; Kato,Kazuhiro; Nishi,Miyuki; Zhao,Xiaoli; Weisleder,Noah; Sato,Chikara; Ma,Jianjie; Takeshima,Hiroshi, 2007, "TRIC channels are essential for Ca2+ handling in intracellular stores." NATURE 448, no. 7149, 78-82 - 78-82.
  • Brotto, Marco; Weisleder,Noah; Ma, Jianjie., 2007, Store-Operated Ca2+ Entry in Muscle Physiology. Current Chemical Biology 1, no. 1, 87-95 - 87-95.
  • Ko,Jae-Kyun; Choi,Kyoung-Han; Pan,Zui; Lin,Peihui; Weisleder,Noah; Kim,Chul-Woo; Ma,Jianjie, 2007, "The tail-anchoring domain of Bfl1 and HCCS1 targets mitochondrial membrane permeability to induce apoptosis." JOURNAL OF CELL SCIENCE 120, no. 16, 2912-2923 - 2912-2923.

2006

  • Hirata,Yutaka; Brotto,Marco; Weisleder,Noah; Chu,Yi; Lin,Peihui; Zhao,Xiaoli; Thornton,Angela; Komazaki,Shinji; Takeshima,Hiroshi; Ma,Jianjie; Pan,Zui, 2006, "Uncoupling store-operated Ca2+ entry and altered Ca2+ release from sarcoplasmic reticulum through silencing of junctophilin genes." BIOPHYSICAL JOURNAL 90, no. 12, 4418-4427 - 4418-4427.
  • Weisleder,Noah; Ma,Jian-jie, 2006, "Ca2+ sparks as a plastic signal for skeletal muscle health, aging, and dystrophy." ACTA PHARMACOLOGICA SINICA 27, no. 7, 791-798 - 791-798.

2005

  • Zhao,X,L; Yoshida,M; Brotto,L; Takeshima,H; Weisleder,N; Hirata,Y; Nosek,T,M; Ma,J,J; Brotto,M, 2005, "Enhanced resistance to fatigue and altered calcium handling properties of sarcalumenin knockout mice." PHYSIOLOGICAL GENOMICS 23, no. 1, 72-78 - 72-78.
  • Fountoulakis,M; Soumaka,E; Rapti,K; Mavroidis,M; Tsangaris,G; Maris,A; Weisleder,N; Capetanaki,Y, 2005, "Alterations in the heart mitochondrial proteome in a desmin null heart failure model." JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 38, no. 3, 461-474 - 461-474.

2004

  • Weisleder,N; Taffet,G,E; Capetanaki,Y, 2004, "Bcl-2 overexpression corrects mitochondrial defects and ameliorates inherited desmin null cardiomyopathy." PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101, no. 3, 769-774 - 769-774.
  • Shah,S,B; Davis,J; Weisleder,N; Kostavassili,I; McCulloch,A,D; Ralston,E; Capetanaki,Y; Lieber,R,L, 2004, "Structural and functional roles of desmin in mouse skeletal muscle during passive deformation." BIOPHYSICAL JOURNAL 86, no. 5, 2993-3008 - 2993-3008.
  • Weisleder,N; Soumaka,E; Abbasi,S; Taegtmeyer,H; Capetanaki,Y, 2004, "Cardiomyocyte-specific desmin rescue of desmin null cardiomyopathy excludes vascular involvement." JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 36, no. 1, 121-128 - 121-128.

2000

  • Milner,D,J; Mavroidis,M; Weisleder,N; Capetanaki,Y, 2000, "Desmin cytoskeleton linked to muscle mitochondrial distribution and respiratory function." JOURNAL OF CELL BIOLOGY 150, no. 6, 1283-1297 - 1283-1297.

Presentations

  • "Desmin Cytoskeleton as Potential Regulator of Muscle Mitochondrial Behavior and Function." 2003, Presented at Experimental Biology,
  • "MG53 as a membrane repair molecule in muscle cells." 2009, Presented at Muscle Excitation-Contraction Coupling Gordon Conference,
  • "Junctophilins as mediates of Ca2+ signaling in health and disease." 2009, Presented at Special Conference on Muscle Physiology,
  • "Repair of cellular membranes as a therapeutic intervention." 2009, Presented at Research Seminar,
  • "Methods of gene delivery into native skeletal muscle." 2009, Presented at Muscle Biology Group Seminar,
  • "Therapeutic approaches for Muscular Dystrophy." 2010, Presented at Executive Council Meeting for Robert Wood Johnson Medical School,,
  • "MG53 Protein Modulated Therapeutic Membrane Repair in Skeletal Muscle." 2011, Presented at Jain Foundation Conference,
  • "Targeting Membrane Repair in Regenerative Medicine in Multiple Tissue Types." 2011, Presented at Research Seminar,
  • "Calcium Regulation in Striated Muscles: Implications for Metabolism and Disease." 2011, Presented at Davis Center for Heart and Lung Research,
  • "TRIM family proteins in membrane repair and metabolism." 2012, Presented at Research Seminar,
  • "Calcium signaling and membrane repair in muscle physiology and pathophysiology." 2012, Presented at Research Seminar Series,
  • "Orai1 mediates exacerbated Ca2+ entry in dystrophic skeletal muscle." 2013, Presented at Biophysical Society Annual Meeting 2013,
  • "TRIM family proteins as regulators of membrane repair in multiple cell types.." 2013, Presented at OSU Spinal Cord Injury Research Meeting (SCRIM) seminar,
  • "Pathophysiology of inherited diseases of the musculoskeletal system." 2013, Presented at IUBMB Workshop on Inborn Errors of Metabolism & Metabolic Disorders,
  • "TRIM protein mediated membrane repair and cardioprotection.." 2013, Presented at OSU Dental Graduate Student Research Seminar,
  • "TRIM family proteins as mediators of cell membrane repair and survival." 2013, Presented at OSU Division of Pharmacology Seminar Series,
  • "Stress-Induced Uncontrolled Calcium Sparks as Dystrophic Signals in Mammalian Skeletal Muscle." 2005, Presented at Biophysical Society Annual Meeting,
  • "Quantal nature of sarcoplasmic reticulum Ca release in mammalian skeletal muscle." 2006, Presented at Biophysical Society Annual Meeting,
  • "Live Cell Imaging of Cell Membrane Repair: from Basic Discovery to Therapeutic Application." 2011, Presented at Annual UMDNJ Technology Symposium,
  • "Compromised Metabolic Response To Short Term Intermittent Hypoxia In mg53-/- Mice." 2011, Presented at American Thoracic Society International Conference,
  • "TRIM protein mediated membrane repair and cardioprotection." 2012, Presented at Invited Seminar,
  • "Injection of encapsulated embryonic stem cells improves cardiac structure and function following myocardial infarction in the absence of tumor formation." 2014, Presented at Cell & Gene Therapy International Conference,
  • "Mitsugumin 53 (MG53) in cardioprotection and metabolism." 2011, Presented at Research Seminar,
  • "Academia and Industry: Finding Your Best Fit." 2011, Presented at New Jersey Postdoctoral Fellow Appreciation Day Symposium,
  • "TRIM Family Proteins in Membrane Repair and Metabolism." 2012, Presented at Davis Heart and Lung Research Institute Research Day,
  • "Ca2+ sparks as a plastic signal for muscle health, aging and dystrophy." 2006, Presented at Research seminar,
  • "Systemic ablation of RyR3 alters the osmotic-stress induced Ca sparks in adult mammalian skeletal muscle." 2007, Presented at Biophysical Society Annual Meeting,
  • "Producing recombinant proteins for therapeutic applications." 2009, Presented at Biotechnology Seminar Series,
  • "Membrane repair defect in muscular dystrophy are linked to altered interactions between MG53, caveolin-3 and dysferlin." 2009, Presented at Jain Foundation Annual Meeting,
  • "Mitsugumin 29 as a sentinel against aging related decline in muscle function." 2009, Presented at International Symposium on Healthy and Diseased Muscle,
  • "Protein Therapeutics for Muscular Dystrophy." 2010, Presented at Jain Foundation Meeting,
  • "Postdoctoral Entrepreneurship Panel." 2011, Presented at National Postdoctoral Association Annual Meeting,
  • "Modulation of membrane repair capacity in muscle through viral gene delivery." 2014, Presented at Indo-Global Healthcare Summit,
  • "Regenerative medicine approaches to the treatment of cardiovascular disease." 2014, Presented at Indo-Global Healthcare Summit,
  • "Molecular characterization of MG53, a muscle-specific TRIM family protein, as a bi-functional regulator of Ca signaling in striated muscles." 2006, Presented at Biophysical Society Annual Meeting,

Papers in Proceedings

2014

  • Agarwal,S; Blazek,A; Young,N; Wu,L-C; Lebelebicioglu,B; Hewett,T; JARJOUR,W; Weisleder,N "PHYSICAL EXERCISE ATTENUATES INFLAMMATION VIA SUPPRESSION OF SYSTEMIC MACROPHAGE ACTIVATION." in World Congress of the Osteoarthritis-Research-Society-International (OARSI). (4 2014).

2013

  • Moloughney,Joseph,Gennaro; Alloush,Jenna; Le-Hoang,Oanh; Weisleder,Noah,Lucas "Membrane repair protein Mitsugumin 53 as a potential therapeutic for the treatment of traumatic brain injury." in Joint Annual Meeting of the ASPET/BPS at Experimental Biology (EB). (4 2013).
  • Orange,Mathew; Ferrante,Christopher; Yan,Rosalie; Tan,Tao; Takizawa,Norio; Lin,Pei-Hui; Li,Haichang; Takeshima,Hiroshi; Weisleder,Noah; Ma,Jianjie "MG53 can Function in Keratinocyte Membrane Repair and Contribute to Excisional Wound Healing in Rodent Skin." in 57th Annual Meeting of the Biophysical-Society. (1 2013).
  • Zhao,Xiaoli; Moloughney,Joseph,G; Zhang,Sai; Komazaki,Shinji; Weisleder,Noah "Orai1 Mediates Exacerbated Ca2+ Entry in Dystrophic Skeletal Muscle." in 57th Annual Meeting of the Biophysical-Society. (1 2013).
  • Karam,Chehade,N; Yi,Jianxun; Manno,Carlo; Deng,Han-Xiang; Xu,Jiajie; Li,Kaitao; Weisleder,Noah; Ma,Jianjie; Cheng,Heping; Zhou,Jingsong "Increased Mitochondrial Superoxide Production in the Skeletal Muscle Derived from a Double-Transgenic Mouse Model of Amyotrophic Lateral Sclerosis." in 57th Annual Meeting of the Biophysical-Society. (1 2013).

2012

  • Weisleder,Noah; Takizawa,Norio; Tan,Tao; Ferrante,Christopher; Chen,Pin-Jung; Yan,Rosalie; Zhao,Xiaoli; Cai,Chuanxi; Takeshima,Hiroshi; Ma,Jianjie "Recombinant MG53 Protein can Increase Membrane Repair Capacity and Improve Pathology in Dystrophic Mouse Muscle." in 56th Annual Meeting of the Biophysical-Society. (1 2012).
  • Moloughney,Joseph,Gennaro; Hersey,John; Tan,Tao; Hsai,Henry; Weisleder,Noah "MG53 reduces cell death associated with hemorrhagic shock ischemia/reperfusion (I/R) injury by increasing membrane repair capacity." in Experimental Biology Meeting 2012. (4 2012).
  • Zhu,Hua; Lin,Pei-Hui; De,Gejing; Choi,Kyoung-Han; Takeshima,Hiroshi; Weisleder,Noah; Ma,Jianjie "PTRF Anchors MG53 to Cell Injury Site for Initiation of Membrane Repair." in 56th Annual Meeting of the Biophysical-Society. (1 2012).
  • Orange,Matthew; Lin,Peihui; Zhu,Hua; Weisleder,Noah; Ma,Jianjie "Additive Phenotype of MG53 and Dysferlin Deficiencies in Membrane Repair Function of Skeletal Muscle Fibers." in 56th Annual Meeting of the Biophysical-Society. (1 2012).

2011

  • Ko,Jae-Kyun; Choi,Kyoung-Han; Peng,Jun; Zong,Wei-Xing; Weisleder,Noah; Lin,Jialing; Ma,Jianjie "Amphipathic Tail-Anchoring Peptide from BFL-1 and Pro-Apoptotic BH3 Peptides Induce Apoptosis Through Different Mechanisms." in 55th Annual Meeting of the Biophysical-Society. (2 2011).
  • Lin,Pei-Hui; Cai,Chuanxi; Weisleder,Noah; Zhu,Hua; Takeshima,Hiroshi; Ma,Jianjie "Non-Muscle Myosin IIA Facilitates Vesicle Trafficking for MG53-Mediated Cell Membrane Repair." in 55th Annual Meeting of the Biophysical-Society. (2 2011).
  • Weisleder,Noah; Takizawa,Norio; Lin,Peihui; Tan,Tao; Chen,Pinjung; Yan,Rosalie; Zhao,Xiaoli; Hwang,Moonsun; Takeshima,Hiroshi; Ma,Jianjie "Recombinant MG53 Binds Lipid Signals on Damaged Cell Membranes to Increase Membrane Repair Capacity." in 55th Annual Meeting of the Biophysical-Society. (2 2011).
  • Zhao,Xiaoli; Takizawa,Norio; Park,Kiho; Choi,Kyoung-Han; Wilkinson,Hilary,A; Zaller,Dennis,M; Weisleder,Noah; Ma,Jianjie "Recovery of the Compromised Ca2+ Spark Signaling in Aged Skeletal Muscle Through Restoration of MG29." in 55th Annual Meeting of the Biophysical-Society. (2 2011).
  • Touchberry,Chad; Elmore,Chris; Tien Nguyen,T; Andresen,Jon; Zhao,Xiaoli; Orange,Matthew; Weisleder,Noah; Brotto,Marco; Claycomb,William; Wacker,Michael "The HL-1 cardiomyocyte cell line exhibits store-operated calcium entry." in Experimental Biology Meeting 2011. (4 2011).
  • Tjondrokoesoemo,Andoria; Li,Na; Weisleder,Noah; Ma,Jianjie "Inositol 1,4,5 Triphosphate (IP3) Receptors Activate Type 1 ryanodine Receptors to Mediate Ca2+ Sparks Signaling in Adult Mammalian Skeletal Muscle." in 55th Annual Meeting of the Biophysical-Society. (2 2011).

2010

  • Ko,Jae-Kyun; Peng,Jun; Choi,Kyoung-Han; Zhang,Zhi; Zong,Wei-Xing; Weisleder,Noah; Lin,Jialing; Ma,Jianjie "Amphipathic Tail-Anchoring Peptide and BH3 Peptide Induced Mitochondrial Permeabilization and Apoptosis are Mechanistically Distinct." (1 2010).
  • Park,Ki,Ho; Zhao,Xiaoli; Yamazaki,Daiju; Pitt,Samantha; Tjondrokoesoemo,Andoria; Komazaki,Shinji; Ko,Jae-Kyun; Lin,Pei-Hui; Brotto,Marco; Sitsapesan,Rebecca; Weisleder,Noah; Takeshima,Hiroshi; Ma,Jianjie "Knockdown of TRIC-B from tric-a(-/-) mice Alters Intracellular Ca2+ Signaling in Skeletal and Cardiac Muscles." in Biophysial Society Meeting. (1 2010).
  • Tjondrokoesoemo,Andoria; Weisleder,Noah; Ma,Jianjie "Compromised Ca2+ Sparks Signaling in the Skeletal Muscle of Diabetic Type 2 Mice." in Biophyscial Society Annual Meeting. (1 2010).
  • Tjondrokoesoemo,Andoria,R; Zhao,Xiaoli; Jia,Weiping; Weisleder,Noah; Ma,Jianjie "GLP-1 Treatment Restores Compromised Ca2+ Spark Activity in Diabetic Skeletal Muscle." in 70th Annual Meeting of the American-Diabetes-Association. (6 2010).
  • Zhao,Xiaoli; Weisleder,Noah "Orai1 Mediates Store-Operated Ca2+Entry in Normal Skeletal Muscle and Exacerbated Ca2+Entry in Dystrophic Muscle." (1 2010).

2009

  • Cheng,Heping; Wang,Xianhua; Xie,Wenjun; Zhang,Yi; Han,Liang; Han,Peidong; Wang,Yanru; Chen,Zheng; Ji,Guangju; Zheng,Ming; Weisleder,Noah; Takeshima,Hiroshi; Ma,Jianjie "CARDIOPROTECTION BY MG53 MEDIATED MEMBRANE REPAIR." (1 2009).
  • Ma,Jianjie; Takeshima,Hiroshi; Cai,Chuanxi; Weisleder,Noah; Komazaki,Shinji; Sunada,Yoshihide "MG53, A MOLECULAR SENSOR OF THE ACUTE MEMBRANE REPAIR PROCESS IN STRIATED MUSCLE." (1 2009).
  • Landstrom,Andrew,P; Garbino,Alejandro; Wehrens,Xander,H; Weisleder,Noah; Ma,Jianjie; Ackerman,Michael,J "Cardiac Junctophilin-2 Expression Silencing Results in Cellular Hypertrophy and Isoproterenol-Sensitive Derangements in Calcium-Handling." in 82nd National Conference and Exhibitions and Scientific Sessions of the American-Heart-Association. (11 2009).

2008

  • Mavroidise,M; Kostavasili,I; Panagopoulou,P; Weisleder,N; Capetanaki,Y "Desmin tail mutation linked to human dilated cardiomyopathy promotes cleavage of the N-terminus and abolishes z-disc localization." in 28th Annual Meeting of the European Section of the International-Society-for-Heart-Research. (4 2008).

2007

  • Zhao,Xiaoli; Thornton,Angela; Campbell,Rachel; Oppong,Yaa; Weisleder,Noah; Ma,Jianjie; Brotto,Marco "Compromised store-operated Ca entry (SOCE) in aged skeletal muscle." in Experimental Biology 2007 Annual Meeting. (4 2007).
  • Landstrom,Andrew,P; Weisleder,Noah; Bos,J,M; Ma,Jianjie; Tjondrokoesoemo,Andrea; Ommen,Steve,R; Olivotto,Iacopo; Cecchi,Franco; Girolami,Francesca; Ackerman,Michael,J "Identification and characterization of a novel mutation in JPH2-encoded junctophilin-2 in an Italian hypertrophic cardiomyopathy cohort." in 80th Annual Scientific Session of the American-Heart-Association (AHA). (10 2007).
  • Weisleder,Noah; Ferrante,Christopher,J; Hirata,Yutaka; Collet,Claude; Chu,Yi; Cheng,Heping; Takeshima,Hiroshi; Ma,Jianjie "Systemic ablation of RyR3 alters the osmotic-stress induced Ca sparks in adult mammalian skeletal muscle." in 51st Annual Meeting of the Biophysical-Society. (1 2007).
  • Li,Na; Zhao,Xiaoli; Weisleder,Noah; Vasilov,Anatoliy; Selvamurugan,Nagarajan; Partridge,Nicola; Ma,Jianjie "Effects of pulsed-electromagnetic field on Ca signaling in osteoblast cells." in 51st Annual Meeting of the Biophysical-Society. (1 2007).
  • Weisleder,Noah; Ferrante,Christopher,J; Hirata,Yutaka; Collet,Claude; Csernoch,Laszlo; Ma,Jianjie "Inhibition of osmotic stress-induced Ca sparks in skeletal muscle by bromoenol lactone, an inhibitor of calcium-independent phospholipase A(2) (iPLA(2))." in 51st Annual Meeting of the Biophysical-Society. (1 2007).

2006

  • Bos,J,M; Batalden,Karin,B; Weisleder,Noah; Tester,David,J; Ommen,Steve,R; Hwang,Moonsun; Ma,Jianjie; Ackerman,Michael,J "Molecular and functional identification of a new pathogenic mechanism in hypertrophic cardiomyopathy: Mutations in JPH2-encodeded jynctophilin-2." in 79th Annual Scientific Session of the American-Heart-Association. (10 2006).

2004

  • Dilly,K,W; Guatimosim,S; Frederick,C; Weisleder,N; Capetanaki,Y; Lederer,W,J "Desmin and calcium signaling in heart.." in 48th Annual Meeting of the Biophysical-Society. (1 2004).
  • Soumaka,E; Rapti,K; Mavroidis,M; Tsangaris,G; Weisleder,N; Fountoulakis,M; Capetanaki,Y "Alterations in the heart mitochondrial proteome due to desmin deficiency." in 44th Annual Meeting of the American-Society-for-Cell-Biology. (11 2004).

2001

  • Weisleder,N; Capetanaki,Y "Exclusion of vasculature involvement in desmin null cardiomyopathy." (6 2001).
  • Mavroidis,M; Weisleder,N,L; Capetanaki,Y "Differential expression of matricellular proteins in desmin null cardiomyopathy." (6 2001).

2000

  • Weisleder,N,L; Capetanaki,Y "Normal heart phenotype in desmin null mice achieved by cardiomyocyte-specific desmin rescue excludes involvement of vasculature in desmin related dilated cardiomyopathy." (12 2000).

Patents

  • Jianjie Ma; Noah Weisleder; Chuanxi Cai. "COMPOSITIONS AND METHODS FOR PREPARING RECOMBINANT MG53 AND METHODS FOR OPTIMIZING SAME."
  • Jianjie Ma; Jae-Kyun Ko; Chul-Woo Kim; Noah Weisleder. "ATAP PEPTIDES, NUCLEIC ACIDS ENCODING THE SAME AND ASSOCIATED METHODS OF USE."
  • Noah Weisleder; Chuanxi Cai; Jianjie Ma. "COMPOSITIONS AND METHODS TO MODULATE CELL MEMBRANE RESEALING."
  • Noah Weisleder; Jianjie Ma. "COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF CARDIAC ISCHEMIC INJURY."
  • Hua Zhu; Noah Weisleder; Jianjie Ma. "COMPOSITIONS AND METHODS FOR THERAPEUTIC MEMBRANE REPAIR."
  • Jiangie Ma; Noah Weisleder; Zui Pan. "Compositions and Methods for Modulating Store-Operated Calcium Entry." Patent number: 8071533
  • JIANJIE MA; NOAH WEISLEDER; HUA ZHU; PEIHUI LIN. "COMPOSITIONS AND METHODS MODULATING MG29 FOR THE TREATMENT OF DIABETES." Patent number: 8603993
  • Jianjie Ma; Noah Weisleder; Chuanxi Cai. "Proteins, Nucleic Acids Encoding the Same, and Associated Methods of Use." Patent number: 7981866
  • Jianjie Ma; Noah Weisleder. "Compositions Comprising MG29 Nucleic Acids, Polypeptides, and Associated Methods of Use." Patent number: 8603992
  • NOAH WEISLEDER; JIANJIE MA. "SERUM MG53 AS A DIAGNOSTIC MARKER FOR TISSUE INJURY." Patent number: 8420338